What is vasculitis and how is it caused?

Clinical features of vasculitis.

1) Coldness, intolerance, numbness and paresthesia in the limbs, especially in the toes, are common early symptoms.

2) Pain is the main symptom of the disease, which is manifested as:

Intermittent claudication: When the patient walks for a distance, the calf or foot muscles develop numbness, soreness, pain, convulsions, weakness and other symptoms, if the patient continues to walk, the symptoms are aggravated, and finally forced to stop, after standing in place and resting for a while, the pain is quickly relieved, and the walking can be continued, but the above symptoms recur after walking. This symptom is called intermittent claudication, and it is typical of insufficient blood supply to the arteries of the lower extremities.

Pain at rest: In severe arterial ischemia, the pain in the affected limb is severe and persistent, and the pain does not persist at rest, and it is difficult to sleep through the night. Even if the toe is ulcerated and infected, the pain is more severe.

3) Limb dystrophy: manifested as thickening and deformation of toenails, dryness, hair loss, atrophy of calf or foot muscles, etc., and ischemic dryness, blackening, necrosis and so on at the end of the toes when the disease progresses and worsens.

The vasculature is a blood vessel, and the arteries and veins are both blood vessels, so the clinical symptoms caused by the blockage of arteries and veins are vasculitis. The full name of vasculitis in Western medicine is thromboangiitis obliterans. It occurs mainly among young and middle-aged people, especially among men who smoke well, and in northern China and some parts of Asia.

**Most are related to cold, hormones or smoking.

It is thought to be due to occlusion due to arteriolar spasm and thrombosis, resulting in ischemia. Half of them are associated with Raynaud's phenomenon, and are more common in men, with smokers being the majority. Smoking is closely related to the course and prognosis of the disease.

One is genetic, 1% to 5% of patients with Buerger's disease have a family history. Many scholars have found that some special sites of human leukocyte antigen are associated with the pathogenesis of thromboangiitis obliterans. The second is long-term smoking, which is also one of the most important forms of vasculitis.

According to the data, 60% to 95% of patients with vaso-obliterans are smokers. Clinical observation has found that smoking cessation can lead to remission in patients with Buerger's disease, and it can worsen if smoking again. Of course, this does not mean that smokers will get vasculitis, after all, only a small number of smokers develop BCB, and some CBANGIITIS patients have no smoking history.

Therefore, smoking may be an important factor in the development of Buerger's disease, but it is not the only one**.

Vasculitis is more common in young men aged 20-45 years, with a history of smoking, a humid environment, etc.

The cause of Buerger's disease is not well understood. However, a large number of clinical experiences tell us that the occurrence of vasculitis is related to long-term heavy smoking. Because most vasculitis occurs in men younger than 45 years of age, some patients develop it at the age of 10 or 20 years.

The patient smokes a lot and smokes second-hand smoke, which causes damage to vascular endothelial cells and causes occlusion of small and medium-sized arterioles; Another factor is cold, some patients live in cold areas, sometimes go to plant rice in the morning, and soak in the cold paddy fields for a long time; Another factor is nutritional disorders, the patient's diet is very small, vitamin C, vitamin B deficiency, resulting in local nutritional disorders, vascular occlusion and reduced blood supply; Another factor is related to the mediation of neurovascularity, when the patient is emotional, the blood vessels constrict, resulting in a decrease in local blood **. Smoking, coldness, and mood swings are the main causes of vasculitis. In addition, infectious factors, studies have found that oral infection, stomatitis and vasculitis are also related to a certain extent, and attention should be paid to avoid oral infection; In particular, some ** infections are related to the occurrence of vasculitis.

At the same time, attention should be paid to avoid oral infections and prevent infection of the limbs, which may prevent or the occurrence of vasculitis in patients.

Smoking genetics has a lot of factors, the encyclopedia came out as soon as I checked it, mine has been optimistic, I hope it will be used as soon as possible, and I will say if I need to find help.

The occurrence of vasculitis is related to the environment of cold waves, which is also the reason for the frequent occurrence of vasculitis in the northern region, the cold and humid environment can easily lead to the slowing down of blood circulation in the blood vessels, and at the same time, cause vasospasm and vascular endothelial damage, and lead to the occurrence of vascular inflammation, which is the so-called vasculitis disease. In addition, the occurrence of vasculitis is also related to trauma, so to stay away from vasculitis, it is necessary to be vigilant for vascular trauma.

Vasculitis is related to smoking, and clinical studies have shown that tobacco contains nicotine, which can cause spasm of small blood vessels, resulting in vascular damage and increasing the incidence of vasculitis. Therefore, to reduce the incidence of vasculitis, attention needs to be paid to quitting smoking.

Vasculitis is caused by ischemia due to occlusion due to arteriolar spasm and thrombosis.

Vasculitis, also known as thromboangiitis obliterans, is a rare chronic segmental inflammatory disease of arterioles and veins, and is more common in the lower limbs. Presents with ischemia, pain, intermittent claudication, decreased or absent dorsalis pedis pulse, migratory superficial phlebitis, and in severe cases, acral ulceration and necrosis.

It is now thought to be due to occlusion due to arteriolar spasm and thrombosis, resulting in ischemia. Half of them are associated with Raynaud's phenomenon, and are more common in men, with smokers being the majority. Smoking is closely related to the course and prognosis of the disease.

The disease is more common in young adults and is more common in the lower limbs. The affected limb presents temporary or persistent pallor, cyanosis, burning and tingling pain, the skin color of the affected limb becomes red when it hangs, it becomes white when lifted, followed by numbness of the toes, pain in the calf muscles, irritation when walking, and disappearance at rest; Superficial phlebitis and edema often occur in the lower legs. On examination, dorsalis pedis pulse is diminished or absent.

As the disease progresses, intermittent claudication and Raynaud's phenomenon may occur, pain worsens at night, and pain in the toes is severe, cyanosis, and then ulceration or gangrene at the end of the toes and blackening, which gradually spreads to the proximal end.

Vasculitis, also known as thromboangiitis obliterans, patients smoke a lot for a long time and live in cold areas, resulting in non-infectious inflammation of small arteries and veins in the peripheral blood vessels of the limbs, intravascular thrombosis, resulting in insufficient blood supply to peripheral blood vessels. The patient feels pain, numbness, and cold in the lower limbs, and the movement is restricted, and in severe cases, resting pain in the lower limbs, even if the patient does not walk, especially at night. Most occur before the age of 45 years, and the vast majority of patients are male.

**Measures to quit smoking, keep warm, and take some vasodilators.

Vasculitis, also known as thromboangiitis obliterans, occurs more often in young adults, more in men than in women, and smokers have a higher incidence rate. Vasculitis is a serious disease caused by vascular occlusion caused by intravascular thrombosis in the arteries, resulting in avascular necrosis of the corresponding limbs.

The initial clinical manifestations of vasculitis are the appearance of pale cyanosis of the ischemic limbs, and redness when sagging. Most patients have pain when walking, also called intermittent claudication, and rest to relieve the pain after walking for a while, sometimes accompanied by superficial phlebitis migrans, and eventually severe pain, rest pain, acral necrosis, and eventually continuous amputation.

Arteriography of the lower extremities can confirm the diagnosis of vasculitis, and once diagnosed, it must be immediately ** to reduce the disability rate, and if it is done properly, it is completely possible. Patients must be reminded that smoking must be stopped! Must quit smoking! Must quit smoking!

Cold, dampness, trauma, smoking, infection, and malnutrition can all be caused.

Vasculitis can be used with the right medicine, early detection and early detection, and no root disease.

Vasculitis is a non-purulent inflammation of the blood vessels of the lower limbs caused by various reasons, resulting in lumen occlusion and varying degrees of ischemia of the limbs. The onset of vasculitis is closely related to smoking and cold, and the condition can be aggravated if the patient smokes again after the first day, so the patient should strictly prohibit smoking, and pay attention to local cold and warmth to prevent trauma.

Vasculitis is thought to be due to occlusion due to arteriolar spasm and thrombosis, resulting in ischemia. It is more common in men, especially smokers. Smoking is closely related to the course and prognosis of the disease.

Vasculitis is possible, it is difficult for Western medicine to achieve curative effects, and my family is completely dependent on Chinese herbal medicine.

Vasculitis is also known as thromboangiitis obliterans, due to the occlusion of blood vessels caused by intravascular thrombosis in the arteries, resulting in the serious disease of ischemia and necrosis of the corresponding limbs, I am an old Chinese medicine doctor, I suffered from vasculitis obliterans 15 years ago, and the condition has been severe to ulceration in recent years. I've been to many places** to no avail, and when I was most in pain, my doctor gave me a few boxes of Nine Worms Antithrombotic Capsules for me to take. I had lost my faith at that time.

The physiological mechanism of vasculitis patients has also undergone a lot of changes, and hormonal disorders generally occur, which has a great effect on the onset of vasculitis, especially patients with thromboangiitis obliterans, the vast majority of whom are male, and they all develop in young adults. Experts point out that prostate dysfunction and excessive loss of prostatic fluid can reduce prostaglandins in the body that have the effect of dilating blood vessels and inhibiting platelet aggregation, and may cause peripheral vasomotor dysfunction and thrombosis, which can lead to vasculitis. In addition, many patients with vasculitis are malnourished.

The occurrence of vasculitis is related to various malnutrition, especially the deficiency of vitamin B and vitamin C, which can easily cause the occurrence of various vascular diseases, including vasculitis.

1.Smoking, nicotine in tobacco can cause inflammatory changes in blood vessels.

2.A history of exposure to cold, exposure to cold, and living in northern regions, vasospasm after exposure to cold can easily induce inflammatory cell infiltrating thrombosis.

3.Trauma can also lead to inflammatory changes in blood vessels.

It is related to cold, dampness, blood stasis, etc.

Smoking. Cold and humid environment, endocrine disorders, etc.

For the clinical manifestations of vasculitis, according to the different stages of vasculitis, the clinical manifestations are also different, first for the initial stage, that is, the ischemic stage of the patient, will show the pallor of the end of the patient's limbs. In addition, the patient will have a decrease in local ** temperature, as well as abnormal sensations such as pinprick and numbness in the patient's local **. In addition, patients will be accompanied by local pain and discomfort during exercise, as well as some patients have migratory superficial phlebitis, in this case, patients need to consider non-smoking, avoid alcohol, and take some vasodilator drugs appropriately**, for patients in the period of nutritional disorders, they will mostly show pain and discomfort in the limbs at rest or at night, and some patients can not sleep, in this case, patients need to consider lumbar sympathetic ganglion resection.

In addition, for some patients in the stage of tissue necrosis, gangrene at the end of the limb is more likely to occur, and patients need to consider amputation in time. The above plan is for reference only, please use the specific drug according to your own situation under the guidance of a professional doctor.