How does diabetes occur?

First of all, there are two types of diabetes.

Type diabetes accounts for less than 10% of diabetes, and most of them are children with immune system problems, after birth, the immune system will attack its own pancreatic beta cells, after which these cells will continue to decrease and eventually disappear, after which the pancreas will no longer produce insulin. But as for why does the immune system attack pancreatic beta cells? I don't know yet.

Type diabetes generally occurs in older people, especially those who eat too much and are obese. Their problem is that the body is not sensitive to insulin, that is, the receptors do not listen to the command of insulin, so the insulin in their body is even high, but the blood sugar just can't go down. As for why the receptor is insensitive?

I don't know yet.

Most people in modern life are Type 2. It is not only the elderly who need to pay attention to their diet, but also the young people. Many modern processed foods contain a lot of sugar.

The absorption of free sugars will make the body's insulin rise, unlike staple foods, the carbohydrates in fruits contain dietary fiber, and the rise in blood sugar is a slow process. The consequence of insulin spikes is that the body is not sensitive to insulin. Blood sugar can't go down.

Hereditary diabetes is more common, and obesity and a sweet tooth are also more likely to get diabetes.

There are all causes of diabetes.

1. Genetic factors.

Usually a considerable number of diabetic patients are almost caused by genetic factors, especially those with a family history of diabetes. If both husband and wife are diabetic, there is a half chance that their child will develop diabetes. If one of the parents has diabetes, although the child will not necessarily get diabetes, but will become a carrier of the diabetes gene, then the prevalence of the child born to him will be relatively large.

2. Bad living habits and other factors.

In addition to genetic factors, the causes of diabetes are caused by the patient's usual bad habits and some other life factors. For example, overwork when you are young, resulting in impaired function, or congenital deficiency and acquired imbalance, or premature aging, and obese people, etc., have excessive fat accumulation in the body, which interferes with the heart, kidneys, lungs, liver and blood vessel disorders. These factors lead to pancreatic failure and insufficient insulin secretion, which can lead to the chance of developing diabetes.

The ** of diabetes is related to its type: first, type 1 diabetes is mainly in young people or adolescents, and the main reasons are: it may be related to genetics, but more importantly, it is related to factors such as viral infection, and it is likely that on the basis of genetic background, infectious factors play a very important role; Secondly, type 2 diabetes is mainly related to factors such as better living conditions, social development, obesity and excessive diet, and increased calories, also known as "wealth disease".

On the one hand, there are irregular living habits, poor eating habits, and on the other hand, there is a small probability of heredity.

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia, which is caused by defective insulin secretion or impaired biological action, or both.

The cause of diabetes is not fully understood, and it is generally believed to be related to genetic factors, obesity, unreasonable lifestyle, age, viral infections, autoimmune system deficiencies, and mental factors.

Diabetes mellitus is a metabolic disease characterized by chronic elevated blood glucose, which is a symptom of long-term disorder of fat, protein and carbohydrate caused by defects in insulin secretion and action, which can cause multisystem damage, resulting in chronic progressive lesions, failure and functional decline of blood vessels, heart, nerves, kidneys, eyes and other tissues and organs, and severe metabolic disorders will occur in severe cases, such as hyperosmolar coma, diabetic ketoacidosis, etc.

For example, the occurrence of type 1 and type 2 diabetes is considered to be related to a combination of genetic factors, environmental infections, immune factors and other factors. Diabetes mellitus during pregnancy is a disorder of glucose metabolism that occurs during a specific physiological period in pregnant women, which is related to the rapid weight gain of patients or the damage of pancreatic islets. Some other specific types of diabetes may be associated with genetic mutations, such as monogenic diabetes.

The World Health Organization has 6 latest classifications of diabetes, namely type 1 diabetes, type 2 diabetes, special types of diabetes, hyperglycemia first detected during pregnancy, mixed diabetes, and unclassified diabetes. Type 2 diabetes is the most common type of diabetes in the world, accounting for 90-95% of all diabetes, so most people with diabetes have type 2 diabetes, the biochemical basis of diabetes is long-term hyperglycemia, and long-term hyperglycemia is generally due to long-term diet is not careful, are eating a high-sugar, high-fat diet, do not pay attention to physical exercise, the formation of pancreatic islet function is impaired, resulting in hyperglycemia symptoms. Long-term maintenance of high blood sugar will cause irreversible damage to the body, and then cause diabetes, so to prevent diabetes, it is necessary to do a good job in blood sugar management.

Diabetes**.

1. Hair **.

The exact nature and pathogenesis of diabetes are not well understood, and it is a combination of genetic and environmental factors. Mainly due to immune-mediated selective destruction of pancreatic B cells.

a) Type 1 diabetes.

1.Genetic factors.

Type 1 diabetes has a certain familial clustering. Studies have reported that the incidence of type 1 diabetes in children of parents with a history of diabetes mellitus is 4% to 11%; Familial clustering of type 1 diabetes between siblings was 6% to 11%; The occurrence of type 1 diabetes in identical twins is less than 50% consistent.

2.Environmental factors.

Type 1 diabetes often occurs in connection with or after certain infections. Common infections include mumps virus, rubella virus, cytomegalovirus, measles virus, influenza virus, encephalitis virus, poliovirus, coxsackievirus, and epstein-barr virus.

b) Type 2 diabetes.

The ** of type 2 diabetes is not very clear, and it is generally considered to be a strongly hereditary or polygenic genetic heterogeneous disease, and environmental factors include obesity, insufficient activity and aging. Its onset is mainly due to insulin resistance with insufficient insulin secretion, which generally precedes insulin secretion disorder; or inadequate insulin secretion with or without insulin resistance. Although type 2 diabetes is genetically heterogeneous, most patients with type 2 diabetes and fasting hyperglycemia are characterized by insulin resistance, impaired insulin secretion, and increased hepatic glucose production.

The causes of diabetes mellitus are related to and different types of diabetes. First, type 1 diabetes is due to the background of its own genetic inheritance, and then it is affected by some acquired factors, such as some poisons or drugs, which destroy the function of pancreatic islet cells, so that insulin secretion is insufficient, resulting in the manifestation of elevated blood sugar.

Second, type 2 diabetes is influenced by genetic background factors, plus some acquired factors, such as long-term unhealthy diet and lifestyle habits, too many calorie intake, obesity, etc., which can lead to the occurrence of type 2 diabetes.

Third, special types of diabetes, which mainly include some blood sugar increases caused by other diseases, such as acute pancreatitis or poor liver function, and other blood sugar increases caused by other endocrine diseases, commonly found in hyperthyroidism, glucocorticoid levels too high or gigantism, or growth hormone levels too high may affect blood sugar.

Fourth, gestational diabetes, this one is more special.

The reason why normal people get diabetes is because of irregular lifestyle, extreme lack of exercise, and love to eat sweets.

The words of diabetes have not yet been clarified. Different types of diabetes** are different. Even within the same genre, there are differences.

In general, genetic factors and environmental factors combine to contribute to the occurrence of diabetes. Mainly due to decreased insulin secretion due to pancreatic islet cell dysfunction. Either the body is insensitive to insulin action, or both.

As a result, glucose in the blood cannot be used and stored efficiently.

Current. Except for some special types of diabetes, the molecular ** of most diabetes mellitus is not clear. There is a genetic predisposition to diabetes. There is a phenomenon of family clustering.

But epidemiological and clinical medical studies have been very clear. The main cause of type 2 diabetes is poor lifestyle. If you want to reduce, the number of people with diabetes in our country. Improving and promoting unhealthy lifestyles and forming a social environment is the fundamental way out.

Diabetes mellitus is a group of disorders of carbohydrate, protein, and fat metabolism caused by absolute or relative insulin insufficiency and/or impaired insulin utilization, with hyperglycemia as the main mark.

The typical clinical manifestations of diabetes mellitus are "three more and one less", that is, polydipsia, polyuria, polyphagia and weight loss, as well as high blood sugar and glucose in the urine, etc., which can cause multi-system damage for a long time, resulting in chronic progressive lesions, functional decline and failure of tissues and organs such as eyes, kidneys, nerves, heart, blood vessels, etc., and acute severe metabolic disorders when the condition is severe or stressed.

Diabetes mellitus is an important cause of cardiovascular and cerebrovascular diseases, death, amputation, blindness, kidney failure, and heart failure.

Diabetes mellitus is different according to different types. The most common type 1 diabetes is viral infection, or the existence of autoimmune problems, which has not yet been fully understood, and current studies have found that it may be related to these infections and immune factors. Type 2 diabetes mellitus is mostly a family cluster, which is determined by certain genes, it may be a single gene, or it may be a polygenic disease plus some acquired factors, such as a long-term high-sugar diet in terms of diet, and excess calories will also trigger diabetes.

In addition, there is a special type of diabetes, such as secondary diabetes secondary to Cushing's syndrome, its primary disease may be in the pituitary gland and adrenal glands, then the pituitary gland and adrenal hormone secretion disorder is one of its **.

1. Genetic factors, there is obvious genetic heterogeneity in type 1 or type 2 diabetes. There is a familial tendency to develop diabetes, and 1 4 1 2 patients have a family history of diabetes.

To put it simply, if there is a problem with the metabolism of sugar in the body, it will cause diabetes.