Do ordinary people need to be tested for cancer susceptibility genes?

If no one in the family has cancer, it is generally not necessary. Some people have many people in their family who suffer from cancer, and they usually consider whether it is genetic, and then go for testing. My cousin and I were doing a screening at Herui Genetics, because my aunt had breast cancer, and we were both more scared, so we did genetic testing at Herui Genetics, but now we are both fine, but we are indeed a high-risk group, so we usually pay more attention to medicine.

Yours has provided me with a steady stream of motivation, and I'm glad you are satisfied.

1. Early prevention and early diagnosis of cancer.

In 2004, Apple founder Steve Jobs was diagnosed with pancreatic cancer, and doctors once asserted that he had less than a 10% chance of surviving for one year. However, Jobs spent about $100,000 on gene sequencing to understand the unique genetic and molecular characteristics of his tumor, and according to the test results, the medical team accurately formulated the best plan for him, selected specific drugs, and reduced the frequency of cell cancerous molecules, and finally extended his life by 7 years.

At that time, gene sequencing was not yet popular, and it was relatively expensive, but today gene sequencing has been well known to ordinary people, and more and more people rely on gene sequencing to extend their lifespan.

Some people ask, the cost of medical examination is cheaper, isn't it possible to detect cancer? Facts have proved that for acquired gene mutations or cancers at a very early stage, they cannot be detected by conventional physical examination items such as B-ultrasound, CT, and MRI, while genetic testing can find potential lesions, and through early prevention, cancer can occur later or not occur, and once cancer occurs, it can also be carried out as soon as possible**.

2. Provide a basis for targeted drugs**.

Traditional chemotherapy drugs cannot distinguish between good and bad cells in the body because they want to inhibit the rapidly growing cancer cells. Once the chemical drug enters the body, it will hit all the cells that are metabolized and proliferated. Targeted drugs target the abnormality in the cancer, with less pain and a higher coefficient.

The purpose of precision medicine is to provide patients with the most advantageous**, and these can only be accurately grasped by genetic sequencing.

3. Guide healthy eating.

Genetic testing gives us clear guidance on the use of dietary and health supplements. According to the results of genetic testing, you can evaluate your digestion and absorption of various foods, tailor-made design of diet institutions, and configure personalized health products according to the absorption of various nutrients. Such diet and health products are the most scientific, safest and most effective.

For example, if genetic testing detects that you have breast cancer and cervical cancer susceptibility genes, the external cause of these two diseases may be vitamin E and protein powder in health products, which are two common health products that many people are taking, which have a good effect on anti-aging and improving immunity, but with your genes, the more you eat, the greater the probability of disease.

If you are detected with a susceptibility gene to systemic lupus erythematosus, you should eat less or no seafood, lamb, protein powder and less sun exposure, which may trigger the development of systemic lupus erythematosus. This is something that only genetic testing can do.

4. Provide personalized medication guidance.

Due to people's genetic differences, the strength of drug metabolism is also different. Improper medication can lead to the occurrence of new diseases, disability, death and other conditions. According to statistics, 10% and 25% of Chinese have weak metabolic genes in the body, which are slow to metabolize specific drugs, which may cause the accumulation of metabolic drugs and adverse reactions.

The vast majority of drug responses vary from person to person.

Real genetic testing costs thousands of dollars per site, and there are many types of cancer, and if you want to test them all, the cost is quite high. At present, some so-called genetic tests are not real genetic tests, but are through the detection of some physiological indicators, under the banner of genetic testing.

Correct selection of drugs to avoid drug abuse and adverse drug reactions Due to individual genetic differences, different people will react differently to foreign substances, so some patients may have drug allergies, redness, swelling and rash when using normal doses of drugs. According to the results of genetic testing, a specific program can be formulated to scientifically guide the use of drugs and avoid drug toxicity and side effects.

Clinical significance:1For the diagnosis of diseases such as the diagnosis of Mycobacterium tuberculosis infection, previously mainly relied on sputum, stool or blood culture, the whole test process needs to take more than two weeks, using the method of genetic diagnosis, not only the sensitivity is greatly improved, but also the results can be obtained in a short time.

2.Understand whether you have the pathogenic genes of familial diseases, ** The risk data confirm that 10% and 15% of cancers are related to genetics, and many diseases such as diabetes and cardiovascular and cerebrovascular diseases are related to genetic factors.

For example, people with cancer or polygenic genetic diseases (such as Alzheimer's disease, hypertension, diabetes, etc.) can find out the genetic genes that cause the disease, and then they can adjust their lifestyle in a targeted manner to prevent or delay the occurrence of diseases.

Cancer is a very serious malignant tumor, and it is very necessary for patients with Xiaoliang in the Cancer Bureau to do genetic testing, because genetic testing is the basis for guiding and selecting the use of targeted drugs.

Patients with gene mutations will have obvious efficacy when using corresponding targeted drugs**, and patients without gene mutations are not suitable for targeted drugs**. The main methods of cancer are surgery, chemotherapy, radiotherapy, targeted drugs, etc., and targeted drugs are very effective methods.

At present, cancer genetic testing mainly targets some solid tumors, such as lung cancer, breast cancer, stomach cancer, esophageal cancer, colorectal cancer, liver cancer, bile duct gallbladder cancer, pancreatic cancer, gastrointestinal stromal tumor, head and neck cancer, cervical cancer, ovarian cancer, endometrial cancer, prostate cancer, bladder cancer, kidney cancer, melanoma, etc.

Molecular testing has revolutionized the cancer paradigm, and cancer has begun to enter a new world of personalization.

At present, in foreign countries, the US FDA (Food and Drug Administration) has mandated genetic testing such as EGFR and KRAS. Another authoritative organization, the NCCN (National Cancer Comprehensive Network**), has included genetic tests such as EGFR, KRAS, ERCC1, RRM1, and HER2 in the guidelines for cancer**. At present, the main technology of cancer gene detection is real-time fluorescence quantitative PCR (RT-PCR), which has the characteristics of high accuracy, strong specificity, high sensitivity, simple operation, wide application range and high throughput.

In China, with the strengthening of international academic exchanges and exchanges, more and more clinical experts have realized the significance and importance of such testing items.

1. People with a family history of cancer or polygenic genetic diseases are the most in need of genetic testing, through which they can know whether they carry genetic disease genes. People who are diagnosed with hereditary tumors can also get a more suitable plan by doing genetic testing. It is reported that the late Apple CEO Stephen Jobs spent $100,000 to sequence the tumor and his whole genome when he was suffering from cancer.

2. People with long-term diseases, such as 80% of liver cancer patients have a history of hepatitis B, and people with long-term stomach diseases belong to the high-risk group of gastric cancer.

3. People who have been exposed to highly polluted environments for a long time or have bad lifestyle habits can understand their propensity for different diseases through genetic testing.

In the past two years, China's genetic testing companies represented by BGI and Daan Gene have developed rapidly in China, and have reached the international leading level in some specific technologies.

If you have a cancer patient, others will need genetic testing.

If it is determined that it is indeed a carrier of mutant genes, it is recommended for women to do breast cancer screening in advance, and to prevent fallopian tube cancer and ovarian cancer, while men need to pay attention to the risk of prostate and male breast cancer.

It is recommended that younger than 40 years old, start breast stool shock screening, the time is once a year, and the screening method is out of mammography, breast MRI can also be considered to detect possible cancer lesions as early as possible.

Considerations for genetic testing.

1. If saliva sampling is performed, patients with mouth ulcers or bronchitis cannot be tested.

2. If blood sampling is carried out, try to avoid eating after 8:00 p.m. the night before sampling, and try not to eat greasy, high-protein food or drink alcohol within 12 hours before sampling.

3. Genetic testing can determine whether the human body suffers from a disease that has not yet been revealed, avoid delaying, and at the same time, pay more attention to rest before genetic testing to avoid overwork.

Although, at present, the world's science does have the ability to exist in such a way as to detect the real existence. However, DAO personally believes that ordinary people will never have the opportunity to encounter it in ordinary life (only encountering "selling dog meat on the head of a sheep", a small part of the real cancer detection, or just something similar).

1. This kind of examination requires the world's top technology. These top technologies in the world generally belong to national scientific research secrets, so the people have absolutely no chance to know that there is this technology. Not to mention that everyone can check it at will.

The scientific research secrets of various countries are researched by themselves with a huge amount of money, and they are "insulated" from being exempted from inspection, mainly to prevent technology theft).

2. This kind of inspection has basically no practical value to the people, and the cost (of each test) is huge. Because you know the result, you can't change it. There is no such thing as a cancer test.

Because the premise of this test is "cancer patients". If you are not a cancer patient, there is a huge and fundamental error in the report of the results of the examination. (Healthy people should do "healthy genetic testing", and only cancer patients should do "cancer genetic testing", which cannot be used to diagnose cancer.)

3. Add one point: if there is really that technology, it is really effective. Then hospitals under the management of the state will naturally be introduced and used (there is money to be made, and the national hospital may not have the money to invest if it has the economic backing of the state?). ）。

The role of genetic testing is to be able to detect the probability of you developing cancer before you don't have cancer, so as to prevent it more accurately, and now medical technology can only detect that you have cancer in the middle and advanced stages of your cancer, at that time you still have to do chemotherapy, take medicine, suffer, in my opinion, the most important thing is to spend money, tens of thousands of dollars to smash in, often in the end can only last a few weeks of life. To put it in a very logical way, genetic testing can prevent you from getting cancer, of course, provided that you make reasonable and accurate prevention based on the genetic test report. Why precision?

There are more than one or two types of cancer, and there are many cancers, and the methods of prevention are different, unless you dare not do anything, and it is unrealistic to prevent cancer at home every day. At the same time, even if you have cancer, genetic testing can help you achieve precision medicine. Drugs are toxic in three parts, and genetic testing is the drug that can help you choose a drug that is more suitable for you.

There are many genetic testing companies nowadays. I recommend Huicheng gene, if you have time, you can learn about it, they are very knowledgeable, the customer service is also very professional, and the service is very good, you can search on the Internet to understand.

The usefulness and accuracy of the test are not the same for different institutions, and the ** is not the same. The accuracy of tumor genetic testing depends on whether the gene tested is associated with the tumor. Institutions have biomedical doctors who are more reliable.

The second is that the cause of each person's tumor is different, there are more than 400 tumors in the human body that are related to the occurrence of cancer, and whether an institution has detected all of them. Thirdly, the effects of different genes are different, and whether the testing institutions are aware of this is to distinguish the effects of different genes. In addition, tumor gene decoding is a step further than genetic testing.

It is provided by Jiaxue Gene.

Genetic testing can detect your chances of developing cancer, which can be high or low. Huicheng Genetic Test can detect the cancer that has been detected and provide you with reasonable ways to prevent cancer according to the chance of cancer.

Genetic testing is not a specialized technique in detecting cancer.

Genetic testing can only detect whether your genes are predisposed to cancer in a certain way. Or maybe you have some kind of cancer.

The occurrence of cancer is mainly due to acquired factors, such as living environment and living habits.

Genetic testing can detect whether genes will develop cancer and tumor lesions in the next 3 to 5 years, so as to prevent them in advance, and you can go to Shengjing Gene to do it.