What is the principle of cold water showering for stress after vaccination of piglets

Piglets have a stress response after being vaccinated and cannot be showered with cold water.

1. In the process of injecting vaccines, due to operations such as culling, piglets are nervous and show panic symptoms, which is a stress response.

2. In the process of epidemic prevention, the action should be light and steady, and the breeder will help the pig to complete the immunization injection, which can reduce the stress response.

3. Cold water drenching pigs can only increase the stress response of piglets, and even induce other diseases.

4. Due to the different individual piglets, individual piglets will have allergies after vaccination, some symptoms are mild, loss of appetite, self-healing after two days, acute allergies, piglets fall to the ground and have difficulty breathing, spitting, trembling, to be rescued with drugs in time, the commonly used drug is adrenaline.

Haven't heard of it, isn't that? The vaccine is already stressful, isn't it another stress to drench cold water again? You're afraid it won't die, are you?

After vaccinating piglets, they often produce different degrees of stress reactions, and in severe cases, they will die due to untimely rescue. The author uses the following methods to prevent and control the stress response caused by piglets in the process of vaccination, and has achieved good results, which are introduced as follows.

1. The clinical symptoms are a few seconds after the injection, vomiting and dyspnea within a few minutes, and severe cases are extremely difficult to breathe, falling to the ground, convulsions of limbs, foaming at the mouth, and angular arch reflexion.

2 Prevention and control methods.

Patients with obvious respiratory symptoms and vomiting should inject 1ml of epinephrine hydrochloride subcutaneously into the neck of the piglet in time to return to normal.

First aid measures should be taken for those who are seriously ill. That is, pat the heart of the piglet several times with your hand.

Artificial respiration must be taken for those who have just stopped breathing, and then put them in a ventilated place, and at the same time subcutaneously inject 1ml of epinephrine hydrochloride, observe at any time, and the second injection is carried out in pigs that fail to return to normal. When injecting swine fever vaccines, try to choose the first immunization after birth to before eating colostrum, and the second immunization should be carried out one week after weaning. Suckling piglets are very likely to be stressed after being injected with swine fever vaccine and then eating breast milk, so when injecting the vaccine, try to catch the hind limbs of the piglets, or separate the piglets to reduce the piglet chirping, so as not to produce a stress reaction.

It is true that after stress, pigs will not eat severe diarrhea and emaciation. Piglets sometimes have edema!

Reason: Each feed has a fragrance and palatability, because the pig's sense of smell is very poor, mainly reflected in the taste, the taste of the pig is 5000 times that of a human!! If you are particularly sensitive to palatability, you will not eat it.

Because of hunger, the villi of the small intestine atrophy, and the absorption of water is incomplete, which leads to diarrhea. Because of long-term poor business - Grill Yebi - emaciation. Because of the nutritional stress, the nutritional edema is over.

1. In order to alleviate immune stress, the chance of contact between pathogens and animals should be minimized. Strengthen feeding management, do a good job in disease prevention and environmental disinfection, ensure that livestock and poultry are healthy and disease-free before immunization, and reduce the stress response of vaccines.

2. Alleviate immune stress through nutritional regulation. Growth inhibition of immunoagonists is due to excessive release of inflammatory cytokines. Therefore, regulating the production of inflammatory cytokines through nutrition is of great significance for alleviating immune stress.

For example, the use of Oldman No. 1 in the vaccination of swine fever, blue ear, pseudo-madness and other vaccines, and the use of Oldman No. 2 when playing foot-and-mouth disease vaccine, can continuously resist immune stress and immune allergies, increase daily weight gain and reduce the feed-to-meat ratio, and can also regulate the immune function of the pig herd and promote the production of antibodies in advance. Therefore, the measures of nutritional regulation have great practical value to solve the immune stress in actual pig production.

3. Strengthen the awareness of immunization, standardize the operation process, properly transport and keep the vaccine, maintain the vaccine equipment, disinfection and sterilization; Make full preparations before immunization, operate in strict accordance with the immunization program and vaccine instructions, the vaccine is ready for use, injected correctly, and the drinking is controlled within 2 hours when drinking water immunization.

4. Immunization must be carried out according to a reasonable immunization program, and antibody testing should be carried out before immunization to ensure the best immunization age. When the level of maternal antibodies is low or uneven, the immune response of livestock and poultry is more severe, and a long-term stress response can occur. When the level of maternal antibodies is high and consistent, the immune stress is smaller, but when the maternal antibody is high, the vaccine can neutralize the maternal antibodies and cannot produce sufficient protection rate, so it is necessary to conduct antibody testing before immunization to ensure the best time for immunization.

5. Choose the best immune pathway. The same vaccine, the immune route is different, and the size of the stress response is also different.

6. After the occurrence of vaccine immune stress, corresponding methods should be taken to treat the symptoms and prevent and treat inflammatory reactions. Severely reacted livestock and poultry are culled and tested for antibodies to determine the need for revaccination.

7. If more than two vaccines need to be vaccinated at the same time, the interaction between vaccines should be considered. If the vaccines do not interfere with each other or have a mutually promoting effect when causing an immune response, they can be vaccinated at the same time, and if they have an inhibitory effect on each other, they should not be used at the same time, otherwise the immune effect will be affected and cause immune stress.

Piglet vaccination is also a serious stress, you can add a little anti-stress additives, for piglets suckling piglet microecological preparation Weizhuang WSP-01 per ton of compound feed add 1kg, and then with the appropriate addition of vitamin C, can improve the stress state, there are cases formal, 3 days can control stress.

Abstract: The immunity of PRRS has always been a difficult problem, mainly because the inactivated vaccine has a large stress response during clinical application. In order to minimize the chance of a stress response, the article reminds immunization implementers to pay attention to the following:

First, the immunization dose should be reasonably adjusted according to the weight of the pig: second, the temperature of the vaccine and the temperature of the weather should be considered when the vaccine is injected. The appropriate temperature of the vaccine is the key to reducing the stress response and ensuring the immune effect. Third, before injection, the diet, spirit, feces and urine of the pig herd should be carefully observed to ensure the health of the pig herd before immunization.

Fourth, PRRS inactivated vaccines themselves do not affect pregnant sows, but stress (especially pain and allergies) during injection is dangerous to pregnant sows. Therefore, pregnant sows should be injected with special caution and care.

This is very simple, just like a newborn baby, not adapting to the environment, temperature, etc., you can properly feed some anti-stress premix, you can solve it.

In the practice of breeding, it was found that a kind of phenomenon that is often accompanied by Tongjian, after the sow disease in the farrowing room was removed, the piglets left behind have been kept "normal", and once transferred to the nursery, it will "break out". Some groups have been stable, and once they are injected with the (ordinary) vaccine, they immediately "burst out". Some meat sows have been stable and can be raised until they are marketed, but once they are mated, they will "burst out" within half a month.

Experts have said that non-plague is most afraid of stress.

Stress can lead to immunosuppression in pigs! In times of stress, the body's adrenocorticotropic hormones increase, and adrenocorticosteroids strongly inhibit NK cell activity. So, what is the role of NK cells?

NK cells are the workhorse of non-specific immunity that directly kills non-plague viruses (infected cells)!

Causes: Stress Increased adrenocorticosteroid inhibition of NK killer cell activity! (stress leads to immunosuppression).

According to the American "Swine Disease" (African Swine Fever Buried Resistant 2019 Edition), Lumutan NK cells and CD8+ T lymphocytes play a key role in the fight against African swine fever virus.

Modern Red Blood Cell Immunology clearly states that red blood cells can promote the activity and proliferation of NK cells and T lymphocytes. Thus, red blood cells relieve immunosuppression after stress!

In practice, it has been found that stresses such as transportation, group transfer, and ordinary vaccination can make "asymptomatic and toxic" pigs "burst out"!

Causes: Stress Increased adrenocorticosteroid inhibition of NK killer cell activity! (stress leads to immunosuppression).

NK killer cells (no antigen presentation required).

Delta-T cells (congenital non-specific immunity to residual osmosis and epidemic) CD8+ T lymphocytes (antigen presentation, lag in ratio) throughout the intestine and respiratory tract (modern erythrocyte immunology) clearly point out that red cells can promote the activity and proliferation of NK killer cells and T lymphocytes. Thus, hematopoiesis relieves immunosuppression after stress!