What is demyelination? What kind of disease is demyelination?

Demyelination refers to nerve fiber damage or under some pathological conditions, due to release cell degeneration or myelin sheath damage that leads to the separation of platelet layers, swelling, fracture, disintegration, and then complete loss, while the axons are relatively preserved. General demyelinating diseases include the central nervous system and the peripheral nervous system, which are divided into myelinating disorder demyelinating diseases and acquired demyelinating diseases.

Dysmyelination disorders are disorders of myelination caused by inherited metabolic defects, mainly seen in various leukodystrophy, such as adrenoleukodystrophy and susceptible leukodystrophy. Acquired demyelinating diseases** include autoimmunity, such as acute disseminated encephalomyelitis, multiple sclerosis, and Guillain-Barré syndrome. Causes of infection such as progressive multifocal leukoencephalopathy.

Causes of dystrophic disorders, such as subacute combined degeneration of the spinal cord due to vitamin B12 deficiency, and pontine myelinolysis caused by rapid sodium supplementation. It also includes carbon monoxide poisoning due to ischemia and hypoxia, delayed encephalopathy, and subcortical arteriosclerotic encephalopathy.

Demyelination occurs when the myelin sheath of the axons of the cerebrospinal cord is lost. There are two categories: myelin destruction; Myelination streaks disorder. Myelitis demyelinating triangularity is currently considered to be an immune-mediated disease with clinical features:

The patients were children and young adults;

Acute onset, common history of cold, fever, infection, rash, vaccination, cold, childbirth or surgery 1 month before the illness;

A thorough neurological examination often reveals evidence of other central nervous system involvement in addition to spinal cord symptoms and signs;

cerebrospinal fluid examination is positive for oligoclonal bands;

Electrophysiology and MRI can detect some subclinical lesions in the brain; MRI reveals abnormal signals of white matter in the brain. Some myelittic demyelinating lesions present:"Pseudoneoplasia"Manifestations, the MRI shows a mild mass effect, mild edema around it, and there may be patchy hemorrhagic signals, which can easily be misdiagnosed as spinal cord tumors. At present, the effect of internal medicine drugs** is not good.

Therefore, neurosurgical intervention is inevitable and necessary.

Demyelinating myelitis is usually acute multiple sclerosis (MS) spinal type, and the clinical presentation is similar to that of postinfectious myelitis, but the progression is slow, and the disease usually peaks within 1 to 3 weeks. The prodromal infection may be subtle, usually incomplete transverse lesions, with weakness or paralysis of one or both lower extremities, with numbness, the level of sensory impairment is inconspicuous or two-plane, and urinary and fecal disorders are present. Evoked potentials and MRI may reveal lesions elsewhere in the CNS.

Demyelination refers to the myelin sheath damage that occurs after the formation of myelin, which is mainly characterized by the loss of nerve myelin, and the relative involvement of neuronal cell bodies and axons is less than a group of diseases, the common symptoms of this disease are limb weakness, paresthesia, vision loss, nystagmus, consciousness disorders, etc., so it is still necessary to go to the hospital to do a blood routine, CT, electroencephalogram and other types of hidden examinations, you can use drugs, such as methylprednisolone, etc., to consume high-protein, high-vitamin, easy-to-digest food.

The classic concept of demyelinating disease is that neurological lesions result in myelin destruction, disintegration, and loss of nerve fibers.

Demyelinating lesions refer to the loss of the maintenance of the nerve by the Schwann somatic cells on the surface of the sympathetic nerve, just like the plastic skin of the cable falling off, and cannot play the role of maintenance and insulation. It is usually caused by ischemic or inflamed nerves or by autoimmune diseases.

Myelin sheath is a structure wrapped around the axon of neurons, and its main function is nerve conduction, and demyelination refers to the loss of myelin sheath caused by various reasons. Inflammatory demyelination and ischemic demyelination are more common. Inflammatory demyelination is more common in various types of autoimmune inflammation, such as multiple sclerosis, neuromyelitis optica spectrum disease, acute penetrating myelitis, acute disseminated encephalomyelitis, and limbic encephalitis due to paraneoplastic syndromes.

Ischemic demyelination is more common in elderly patients with risk factors for atherosclerosis and cerebrovascular disease, and generally has no obvious clinical symptoms, and severe cases may have dizziness and memory loss. Less commonly, metabolic and dystrophic demyelination, such as Wernicke's encephalopathy, leukodystrophy, and pontine myelinolysis.

The causes of the formation of myelin diseases are divided into congenital and acquired formations. Congenital formation of hereditary diseases; The main causes of acquired development include immune factors, such as multiple sclerosis and neuromyelitis optica, viral infections, and some demyelinating diseases caused by ischemia, hypoxia, or poisoning. In some patients, demyelination changes are caused by acute disseminated encephalomyelitis or due to lack of various nutrients, and multiple sclerosis and neuromyelitis optica are found to be inseparable from autologous humoral immunity, cellular immunity, T lymphocyte immunity, and B lymphocyte immunity.

Demyelinating disorders include central nervous system demyelination and peripheral nerve demyelination. Demyelination of the central nervous system refers to diseases characterized by destruction of the myelin sheath of the brain and spinal cord.

There are two categories: hereditary and acquired: hereditary is mainly caused by genetic factors, such as leukodystrophy and other related diseases, and patients will have intellectual disability, seizures, limb weakness and other changes.

Acquired demyelinating disease usually refers to immune-mediated disease, such as multiple sclerosis. Peripheral nerve demyelination diseases mainly refer to Guillain-Barré syndrome.

Dehydration is a disease caused by overwork, just like the demyelination of the hand, which is caused by the frequent exercise of the hand.

This is actually a disease in neurology, you must go to the neurology department, and the doctor is no problem.

What kind of disease is it, no matter what kind of disease it is, if you are sick, or hurry to the hospital to take a look, you can go to the lobby to ask the guide, which department to see, and then check **.

In fact, it can only be said that your body's low immunity is the cause of these diseases.

If you say that laughter is a disease, if you say what disease, this disease should be the one who laughs, and if he should say it, you can watch the next song.

Demyelination refers to the damage of the myelin sheath that occurs after the formation of myelination, and demyelinating diseases are a group of diseases characterized by the loss of nerve myelin and relatively mild involvement of neuronal inclusions and axons, including hereditary and acquired. Hereditary demyelinating diseases mainly refer to leukodystrophy, which is more common in children. Acquired demyelinating diseases are further divided into two categories: central and peripheral.

The most representative peripheral demyelinating diseases are acute and chronic inflammatory demyelinating polyneuropathy. Central demyelinating diseases include multiple sclerosis and acute disseminated encephalomyelitis.

It is a kind of nervous disease, and now it is slowly used to warm the meridian and marrow decoction.

Diseases of the nervous system.

Beijing Deshengmen Hospital of Traditional Chinese Medicine - Liu Quanpeng - Department of Impotence - Deputy Chief Physician - What is the ** and pathogenesis of demyelinating lesions.

The classic concept of demyelinating disease is that neurological lesions lead to myelin destruction, disintegration, and loss of nerve fibers. Demyelinating diseases in the narrow sense usually refer to idiopathic inflammatory demyelinating diseases of the central nervous system (IIDDS), represented by multiple sclerosis (MS), and also include neuromyelitis optica spectrum disease (NMOSD), anti-myelin oligodendrocyte glycoprotein immunoglobulin G antibody-related disease Mogad