Does the third generation of test tubes have to be tested after raising the capsule?

Yes, whether it is a three-day 5-year-old screening or a 5-day 5-pair or 23-pair, it is all capsule-raising, 3 days and 5 pairs just say that 3 days to develop to 6 to 8 cells can be tested, but it is still necessary to raise to the 5th day to see if the embryo can reach the freezing level. In fact, it is the process of raising the bag.

About screening: There are 5 and 23 pairs of chromosomes for screening, and there are day 3 screening and day 5 screening. You can choose according to your own situation.

The 23 pairs of chromosomes are all the chromosomes of the human body.

5 pairs of chromosomes refers to the third generation of test-tube PGD technology, which can screen for 13 (trisomy (Edwards syndrome (Down syndrome), X (Duchenne muscular dystrophy), Y (acute myeloid leukemia), 5 pairs of chromosomes, and ensures the quality of embryos.

Disadvantages: Only 5 common human chromosome diseases can be screened, PGD technology has certain requirements for embryo quality, and there may be no results of healthy embryo transfer.

There are actually only 23 pairs of 24 pairs of chromosomes, which refers to the third generation of test-tube ACGH technology, which can screen all 23 pairs of chromosomes in the human body, ensure the highest quality of embryos, and have a high success rate of transfer and pregnancy and childbirth. Disadvantages: High requirements for embryo quality, there is a possibility that there will be no results of healthy embryo transfer.

Many customers are struggling to choose 5 pairs or 23 pairs of chromosomes, always feeling that they are afraid that 5 pairs are not as advanced as 23 pairs, and they are worried that the screening is too harsh and the number of embryos available is not much.

In fact, the 5 pairs and 23 pairs of chromosomes are screened for the third generation of test-tube PGD, and there are no genetic diseases and chromosomal abnormalities for both couples.

In terms of 5 pairs of screening, it is enough to meet the needs, and if it is some genetic diseases, chromosomal abnormalities, etc., it is necessary to select 23 pairs to select the best quality embryos;

In addition, if the customer is relatively young, the number of embryos is very large, of course, you can also choose 23 pairs, if the number of embryos itself is small, it is recommended to choose 5 pairs of chromosomes for screening.

About the 3-day screening and 5-day screening: In addition to the 5 pairs and 23 pairs of chromosome screening that everyone is concerned about, embryo culture to 3-day screening or 5-day screening night makes many customers scratch their heads, and the third day is embryo development.

Screening is done when there are more than 6 cells, screening the early embryo, taking one cell from it for testing, and the fifth day is when the embryo develops to hatch the blastocyst.

Screening (what we usually call HGB) is done at the stage, and 4-5 cells are taken from it for testing.

Therefore, there will be abnormal results screened on the third day, and it will be normal to sieve on the fifth day. Having said all this, in the end, everyone only needs to choose 3 days of screening if the number of embryos is small, and 5 days of screening if the number is large.

Yes, the general name for 3 generations of test tubes: genetic screening before transplantation.

Yes, genetic screening can only be done after the sac is raised.

In general, it takes about 3 days for laboratory embryo culture, and after 3 days, high-quality embryos can be selected for transfer, but sometimes embryos are developed into blastocysts and then transferred, that is, about the fifth day of embryo culture. If you do a five-day screening, you will definitely need to raise your bag.

To put it simply, after egg retrieval and fertilization, embryos are generally cultured in the laboratory until the third day, mostly eight cells and seven cells, which is called [fresh embryo].

If there are many fresh embryos, it is called [frozen embryos] if they are directly frozen for the next transfer.

Now, in order to increase the success rate, the fresh embryo on the third day will continue to be cultured until the fifth or even sixth day or more, and the embryo will grow into a cell mass with a blastocyst cavity, which is called a blastocyst. - This process is called "Raising Bags".

Blastocysts are the best, and IVF success rates are the highest. However, not everyone is raised, and not every level of embryos is qualified to raise, and the success rate of raising sacs also varies from person to person, and embryos will die in the process of raising, which is the so-called failure of capsule raising.

When doing IVF, do you have to raise blastocysts? The doctor told the truth and found out.

Understand that in IVF, the general embryo transfer is carried out on the third day after egg retrieval, and the embryo at this time contains 5 8 cells, while the blastocyst refers to the embryo cultivated in vitro for 5 6 days, reaching hundreds of cells, and the implantation into the woman's uterus at this time is called blastocyst transfer.

There is no doubt that blastocyst transfer has a higher implantation rate than normal embryos because blastocysts are of better grade and develop faster. For women who are not physically fit for multiple pregnancies, blastocyst transfer can achieve a higher pregnancy rate and reduce the risk of multiple pregnancies.

However, blastocyst transfer is not suitable for all patients, not all embryos can be cultured in the laboratory to achieve blastocyst grade for transfer, and only 40-50% of embryos are able to develop to the blastocyst stage. Blastocysts have high requirements for the quality of embryos, and for patients with a small number of embryos and poor quality, it is very likely that the blastocyst stage will not be cultivated, resulting in the total destruction of embryos. For such patients, it is generally recommended to transfer as soon as possible, some embryos cannot survive in the laboratory environment, and may survive in the uterus, after all, the uterus is the best survival of the embryo, rooted in the environment.

Therefore, whether or not to transfer blastocysts depends on your personal situation, and I hope it will be of reference value to you!!

Advantages of blastocyst culture

1.Blastocysts are more in line with the physiological state of the uterus.

Under normal circumstances, it is impossible for the embryo to reach the uterus within the 3rd day, and the number of days for the blastocyst to be implanted in the uterus is just equal to the time when the embryo enters the uterus under normal circumstances, so the blastocyst is more synchronized with the endometrium.

2.Favors the selection of embryos.

When cultivating blastocysts, a batch of embryos with no developmental potential will be automatically eliminated, and the embryos that can develop into blastocysts indicate that the embryos themselves have better developmental potential and stronger tolerance.

3.A single embryo prevents multiple pregnancies.

Due to the good quality of the blastocysts, a single blastocyst transfer is generally performed, thus avoiding the risk of multiple pregnancies.

Disadvantages of blastocyst culture

1.The blastocyst culture cycle cancellation rate is high.

Although the blastocyst pregnancy rate is higher than that of eight-cell embryos, not every eight-cell embryo can develop into a blastocyst, and even high-quality embryos have the possibility of blastocyst-free buddy trousers, resulting in no transferable embryos.

2.High requirements for culture conditions and embryo quality.

In addition to high requirements for embryo quality, blastocyst culture also requires higher laboratory conditions, such as more professional laboratory personnel, high-quality indoor environment, more suitable temperature, higher quality laboratory air, more hypoxic incubators, etc.

Should blastocysts be raised?

If the blastocyst is not directly transferred, the implantation rate is lower than that of the blastocyst, the doctor will usually be willing to transplant two or more to increase the pregnancy rate, if the blastocyst culture requirements are high, if the patient's embryo development potential is poor, it may stop developing and stagnate in the 3rd day stage, and wait until the 5th day there will be no embryos to the patient for transfer.

Need yo 1Transplantation of the blastocyst is more in line with the mechanism of pregnancy in the human body 2Blastocyst culture can further detect embryo quality3The implantation rate of blastocysts is high, and the probability of pregnancy is high4It can reduce the risk of ectopic pregnancy.