Mesalazine suppositories are effective with what oral drugs and use

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Mesalazine suppositories were well tolerated, and the main adverse reactions were:

Occasional abdominal discomfort, diarrhoea, flatulence, nausea and vomiting; Headache, dizziness may be seen in individual patients; As with salicylic acid and its derivatives, allergic reactions to mesalazine suppositories are non-dose-dependent.

Rarely, allergic redness and swelling, drug fever, bronchospasm, peripheral pericardial myocarditis, acute pancreatitis, and interstitial nephritis may be seen in rare patients.

During the use of mesalazine**, alveolitis occasionally occurs, and in some cases, pancolitis may occur.

Under certain conditions, some drugs with a similar structure to mesalazine can cause lupus-like syndrome, so the possibility that mesalazine may also cause this reaction cannot be ruled out.

Other adverse reactions:

Occasionally, muscle pain and arthralgia may be observed; The chemical structure of the active component may cause an increase in the level of methaemoglobin; Hematologic changes, including aplastic anemia, agranulocytosis, pancytopenia, neutropenia, neutropenia, leukopenia, and thrombocytopenia, have been reported in isolated cases following the use of mesalazine-containing drugs. Occasionally, liver inflammation (hepatitis) has been reported, and in rare cases, liver function parameters such as elevated levels of ammonases have been reported.

The following patients should use this product with caution: 1 Those who are allergic to salicylic acid or its metabolites or active ingredients are prohibited; 2. Patients with severe liver and kidney insufficiency are prohibited; 3 Patients with gastric and duodenal ulcers are prohibited; 4. Those with hemorrhagic constitution (easy to cause bleeding).

(1) The use of this product should be monitored. (2) During the ** period, under the guidance of the doctor, blood counts and urine tests should be noted. In general, these tests should be carried out within 14 days of the first day.

Thereafter, every 4 weeks of medication, the corresponding examination should be carried out, and this examination should be carried out 2 to 3 times. If there are no abnormalities, serum urea nitrogen (BUN), serum creatinine, and urine sediment should be done every 3 months to reflect renal function. (3) During the period, pay attention to monitoring the methemoglobin level.

4) Patients with pulmonary dysfunction, especially those with asthma, should be closely monitored during the ** period. (5) Patients who are allergic to preparations containing sulfatase can only use this product under medical monitoring. If there is an intolerable reaction, such as acute abdominal pain, cramps, fever, severe headache and**erythema, etc., this product should be discontinued immediately.