What is the cause of the toxic reaction of the drug

a.An allergic reaction.

b.A wandering reaction that occurs when using a dosage that is not related to the purpose of the **.

c.Reactions caused by excessive dosage or prolonged use.

d.A specific reaction to an inherited abnormality of biochemical machinery.

Correct answer: Reaction caused by excessive dosage or prolonged medication.

Zheng's accurate answer:

a.The dosage is too large.

Answer]: c. When the dosage is too large, the drug is not used for too long, or the body is purified to the drug sensitivity is too high, the harmful counter-detection should be called a toxic reaction. The type and severity of toxic reactions depend mainly on the physicochemical properties of the poison, the state of exposure, and the sensitivity of the biological system or individual.

Answer]: A harmful reaction that occurs when the dose is too large or the drug accumulates too much in the body is called a toxic reaction. It is a serious drug reaction, but it can be predicted and avoided.

Answer]: C Analysis: Drug toxicity refers to the serious adverse reactions of serious functional disorders and organic damage caused by drugs (E error).

It is related to the excessive dosage of the drug (error A), the medication time is too long (error D), and it is also related to individual allergies (correct staring). Most drug toxicities can be predicted (b-error). So the answer is c.

Answer]: The toxicity reaction is generally caused by excessive dosage or too long time, and the serious adverse reaction caused by excessive accumulation of the drug in the body. Sometimes the dose is not large, but the body can be too sensitive to the drug.

Most drugs have certain toxicity, for example, the drug digoxin for chronic cardiac insufficiency can cause arrhythmias, and salicylate can cause nausea, vomiting, tinnitus, etc. Toxicity caused by overdose in short-term repression is called acute toxicity, which mostly impairs circulatory, respiratory and nervous system functions. The toxicity that occurs gradually due to the accumulation of drugs in the body during long-term use is called chronic toxicity, which often damages the functions of liver, kidney, hematopoietic organs and endocrine organs.

The carcinogenic, teratogenic, and mutagenic effects of drugs belong to the special toxicity of chronic toxicity. 【Test Center】Toxicity characteristics of drugs.

Answer]: a, b, c, d, e

This question examines the causes of drug toxicity. Toxic causes include: containing toxic groups; Produces non-** effects on non-binding targets (including non-** sites binding to targets, ** sites or non-** sites binding to non-targets); inhibition of HERG; Metabolic effects (including inhibition and induction of liver enzymes, strong toxicity of metabolites).