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Be aware of the possibility of gout.
There is a substance called purine in the human body, which mainly exists in the form of purine nucleotides, which plays a very important role in energy**, metabolic regulation and composition of coenzymes. When its metabolism is disturbed, it can cause gout.
Purines go through a series of metabolic changes, and the final product formed is called uric acid. Uric acid has no physiological function in the human body, under normal circumstances, the uric acid produced in the body, 2 3 is excreted by the kidneys, and the remaining 1 3 is excreted from the intestines.
Uric acid is constantly produced and excreted in the body, so it maintains a certain concentration in the blood. The amount of uric acid per liter of blood in a normal person is less than 0 42 mmol for men and no more than 357 mmol for women. In the process of purine synthesis and decomposition, there are a variety of enzymes involved, due to the congenital abnormality of enzymes or some unspecified factors, metabolism disorders, so that the synthesis of uric acid increases or decreases excretion, and the result can cause hyperuricemia.
When the concentration of uric acid in the blood is too high, uric acid is deposited in the joints, soft tissues, cartilage and kidneys in the form of sodium salt, causing foreign body inflammation in the tissues, which has become the bane of gout.
Gout is a metabolic disease that you should do as directed by your doctor**.
Clinical manifestations of gout and**.
Gout is a group of diseases caused by disorders of purine metabolism. Its clinical characteristics are hyperuricemia with gouty acute arthritis, tophi deposition, tophi chronic arthritis and joint deformity, which often involve the kidneys and cause chronic interstitial nephritis and uric acid nephrolithiasis. The disease can be divided into two categories: primary and secondary, and the primary disease is caused by a small number of enzyme defects, most of which are of unknown origin and are hereditary diseases.
Secondary cases can be caused by a variety of causes such as certain malignant tumors, kidney disease, and blood diseases.
Clinical manifestations》The main clinical manifestations of this disease are arthritis, tophi and renal damage.
Acute gouty arthritis is the most common presenting symptom, with a rapid onset, severe pain, and more frequent nighttime attacks, with redness, swelling, heat and pain around the joints. More than half of the patients have hallux, metatarsophalange, ankle, knee, knee, finger, wrist, and elbow joints, and the acute attack can resolve spontaneously within a few days to weeks. Alcohol consumption, clammy, fatigue, traumatic surgery, and infection are all contributing factors.
Acute inflammation can lead to joint stiffness and deformity.
Tophi is a deposit of urate that can be deposited anywhere, such as under the skin, in the ear chakra, between the fingers, and near the metacarpophalangeal joints.
About 1 3 of the patients with gout who have been suffering for a long time have renal damage, which is mainly manifested by proteinuria and decreased urine concentration function, and progresses from chronic azotemia to uremia syndrome. Primary gout 20 -25 complicated by uric acid urinary tract stones, and some are even the first symptoms of gout.
Don't be careless, go to the hospital and check it out.
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Bone cancer refers to the skeletal system, like other organs, that suffers from tumors of any tissue component or metastatic lesions from other organs. Tumors of the bones can occur in bone cells, hematopoietic components of bones, cartilage, and fibrous or synovial components. Other tumors can arise from musculosculoskeletal nerves, blood vessels, and adipose tissues of the musculoskeletal system.
In the early stage, there are often no obvious symptoms, if it grows out of the bone, due to the compression of the surrounding soft tissues, it can cause pain or functional problems, benign tumors, can also make the structure of the bone change, the bearing effect is weakened and pathological fractures occur (this is the most common), bone malignant tumors, because of its rapid growth, often have obvious swelling and tenderness of the limbs, and even ** fever, blood vessel distension. The direct response of bone cancer is pain, which is a different feeling of pain, and the most significant feature is quiet pain, the quieter it is, the more painful it is.
In general, primary bone tumors tend to occur in the long bones of the limbs; Secondary bone tumors are more common in the pelvis, spine, and femur.
Medium-Stage Symptoms of Bone Cancer Medium-stage symptoms of bone cancer are between early and advanced symptoms and progressive.
Symptoms of advanced bone cancer.
1.The general symptoms are the same as those of other cancer patients, such as loss of appetite, weight loss, and fever.
2.Pain in the affected area, localized lumps and swelling of the joints and limbs.
3.The movement of the joints and limbs of the affected area is restricted.
4.Affected area ** ulcerated.
5.There will be numbness in the distal extremity of the affected limb due to compression of the nerves and blood vessels.
6.Pathological fracture or deformation occurs.
7.The most typical symptom of bone cancer is bone pain, which is especially important if the bone pain is more pronounced at night than during the day.
Symptoms of metastasis and spread of bone cancer What exactly is bone metastases? Bone metastases are cancers in other parts of the body that metastasize to the bones, making the bones like they have been eaten by insects, losing the strength to support the body, causing bone pain or fractures.
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Disease analysis: Heel pain is a common disease, and the diseases of heel pain include heel fat fibrositis, periachilles tendonitis, heel bursitis, calcaneal spur, plantar aponeurositis, calcaneal bone disease, talar arthritis, etc., guidance:
Do a test and take a x-ray to see if there is a bone spur hyperplasia. The use of Chinese herbal medicine to invigorate blood circulation and dispel blood stasis, tonify the kidneys and strengthen bones, foot massage and internal and external use and other methods such as cultivation and cave cultivation will have a good effect.
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What is the heel spur and what should be done with the heel pain caused by it Under normal circumstances, at both ends of the joint bone, covered with a layer of smooth and elastic cartilage, when the heel joint moves, the friction coefficient of cartilage against cartilage is lower than that of ice against ice, so that the wear and tear of the joint is reduced to a minimum.
Chondrocytes contain a lot of water, like a sponge, which thins when pressurized, and returns to their original thickness when the pressure is relieved. The elastic deformation of the cartilage of the heel joint during weight bearing can reduce the impact of movement and **, and the elasticity of this cartilage is very important to resist wear and tear. So what are the manifestations of heel bone spurs?
Manifestations of heel bone spurs: long bone spurs in the heel can cause deformation, redness and swelling of the heel, and heel pain when walking, especially when you wake up in the morning.
There are many causes of heel pain, among which due to the aging of the body, the calcaneal tuberosity degenerates and calcifications, which can also lead to fat paditis and bursitis to form heel pain. Heel fat paditis is caused by long-term pressure on the heel and the feeling of wind and cold, which causes inflammation of the heel pad, which is manifested as swelling of the heel soles, and deep tenderness when the underlying tender inflammation spreads to the calcaneal periosteum or bursa. A small number of patients are caused by heel bone spurs.
Attention should be paid to eating and drinking, choosing loose and suitable shoes, and adding soft pads inside the shoes; Long-term foot exercise can enhance the strength and elasticity of muscles and ligaments; Pay attention to the combination of work and rest, do not stand and walk for too long, soak your feet in warm water every night to promote local blood circulation to avoid the occurrence of heel pain. In the above situation, experts recommend using a big red box combination for foot pain relief. Stick to the course of treatment.
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Concept] Pain that occurs below the ankle joint, including foot heart pain, heel pain, toe pain, etc., are all in the range of foot pain.
Identification] common syndromes.
Foot pain for liver and kidney loss: the main clinical manifestations are heel pain on one or both sides, or foot heart pain, local redness and swelling, and inability to stand and walk for a long time. Dizziness and tinnitus, soreness in the waist and knees, dizziness in the eyes, pale or red tongue, weak pulse or thin strings.
Qi deficiency and blood deficiency foot pain: common heel pain, no redness and swelling of the skin, slow pain during daytime activities, aggravation of pain at night, fatigue and fatigue, pale complexion, fear of sweating, pale tongue, tooth marks on the side, weak or thin pulse.
Cold and damp stagnant foot pain: mostly in the toes, the lower limbs are sleepy and weak when walking, the pain is even lame, the calves are sore, the skin is cold and pale, and gradually turns purple and dark, the affected limbs are afraid of cold, numbness and stinging, especially at night, the tongue is pale and pale, and it can become a gangrene imitation if it does not heal for a long time.
Rheumatism and foot pain Foot pain, aggravated by rain and cold, often combined with pain and swelling of the joints of the limbs, unfavorable flexion and extension, heavy lower limbs, thin white tongue, floating pulse or slow wetting.
Differential analysis.
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Analysis: In this case, it is necessary to pay attention to the possibility of muscle strain on the soles of the feet, the possibility of rheumatic diseases, and the possibility of other causes, such as rheumatoid and old injuries to the affected area.
Guidance: Pay attention to the protection of the affected area, oral loxoprofen capsules, Xiaohuo Luo pills and other drugs to carry out**, if necessary, go to the surgery for timely examination of the affected area, as well as rheumatoid factor determination.
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