Is thrombocytopenia after a blood transfusion a medical malpractice

This is an adverse immune response after blood transfusion, not a medical malpractice, because one: there is no human fault, neither the wrong blood type and components are transfused, and the wrong method is used, and it belongs to the immune response of the patient's own physique, which is unpredictable and irresistible, and two: it does not constitute certain consequences, such as surgery, is it an accident if you leave a scar?

If you know that there is such a reaction and go further**, unless it is a last resort, it is a medical malpractice.

1. The examination results after blood transfusion must exclude errors in specimen collection, and the most important influencing factor of platelet examination results is the production of small clots invisible to the naked eye in blood specimens, which can also cause pseudopenia. It is recommended to review the results.

2. The adverse reactions after blood transfusion are mainly allergies, fever, hemolysis, etc. If platelet testing is the case, it is generally considered to be due to the influence of other drugs.

3. Article 33 of the "Regulations on the Handling of Medical Accidents" does not belong to medical accidents under any of the following circumstances: (4) Adverse consequences caused by no-fault blood transfusion infection.

It's definitely not medical malpractice, it's a normal reaction.

Causes of thrombocytopenia.

1) Decreased or ineffective platelet production dies:

2) Excessive platelet destruction.

3) Excessive retention of platelets in the spleen: most commonly in hypersplenism.

Refer to my space.

Thrombocytopenia transfusions are a relatively common method, but transfusions are not intended to go within.

More for emergency purposes, blood transfusion can allow platelets to be lifted quickly, to avoid the occurrence of emergencies, thrombocytopenia patients can generally maintain seven to fourteen days after blood transfusion, one to two weeks later, the metabolism will basically run out, platelets will also recover a relatively low value.

Some patients will recover quickly after blood transfusion, and they think that the effect is very good, so patients and their families cause certain misunderstandings, which may lead to the aggravation of the condition, of course, there are some patients who do not have any changes in blood routine after blood transfusion, which may be related to the patient's physical condition, or what is the reason for the examination according to the physical condition, and at the same time, it is also necessary to consider not transfusing blood, because blood transfusion has no effect.

Hello, there are too many causes of thrombocytopenia, such as insufficient bone marrow platelets, leukemia, aplastic anemia, paroxysmal nocturnal hemoglobinuria, alcoholism, megaloblastic anemia, some bone marrow diseases, etc., so you have to go to the hospital to check it out first** before you can treat the cause**.

Ineffective platelet transfusion refers to the fact that the patient is in a platelet refractory state after receiving an adequate dose of platelet transfusion, that is, the patient's circulating blood platelet count has not been effectively improved or the clinical bleeding manifestations have not been significantly improved.

Factors influencing the effectiveness of platelet transfusions.

1) Platelet quality: number of platelets; leukocyte contamination; retention period; Preservation bag type; Temperature; **。

2) Alloimmunization: HLA antibodies; HPA antibodies; ABO antibody rotten limbs.

3) non-alloimmunization: fever; Infect; dic；bmt；splenomegaly; drug-induced antibodies; circulating immune complexes; Autoantibody.

At this time, prophylactic and ** platelet transfusion is the most effective hemostatic measure.

1.Thrombocytopenia, severe thrombocytopenia with severe bleeding caused by various reasons, especially severe aplastic anemia, acute leukemia, malignant lymphoma and other tumors after intense chemotherapy, high-dose radiotherapy and bone marrow transplantation, acute radiation sickness, fatal bleeding (such as severe idiopathic thrombocytopenic purpura, thrombotic thrombocytopenic purpura, etc., which are at risk of intracranial hemorrhage). Generally speaking, when the platelet count is less than 20 109 L, it may be accompanied by extensive and severe bleeding, such as hemoptysis, massive bleeding in the upper chemical tract, intracranial hemorrhage, etc.

At this time, prophylactic and ** platelet transfusion is the most effective hemostatic measure. When platelet function is normal and the count is greater than 20 x 109 L, the bleeding is generally mild, and platelet transfusion is usually not necessary, so as to avoid the production of alloantiplatelet antibodies after repeated platelet transfusions, which will reduce the efficacy or even be ineffective when emergency platelet transfusions are required in the future.

2.Severe platelet deficiency Platelet weakness, macroplatelet syndrome, platelet von Willebrand disease.

1. Transfusion of a large amount of stored blood causes thrombocytopenia. Blood collection with conventional methods can cause platelets to adhesion, condense on the surface of the foreign body, and be destroyed. If the blood bank has been in the bank for more than 48 hours, there are no survivable platelets that can be used for hemostasis.

If a large amount of blood is transfused (e.g., 5000 ml of blood transfused continuously within 48 hours), platelets will definitely decrease; If the transfusion of stock blood reaches 7000 ml, it can bleed, and children use exchange transfusion**** When some diseases are used, if they use stock blood, it can also cause the same consequences.

2. Thrombocytopenia caused by transfusion of incompatible blood types. This condition is thought to be caused by disseminated intravascular coagulation, which increases platelet consumption.

3. Purpura after blood transfusion. Thrombocytopenic purpura is mainly caused by changes in the body's immune function. This disease mostly occurs in middle-aged multiparous women, thrombocytopenia, ** mucosal hemorrhage, and even the risk of intracranial hemorrhage one week after blood transfusion.

4. Repeated blood transfusions produce antiplatelet antibodies. After 50 blood transfusions, 25% of patients with 50 percent of patients had platelet transfusions that disappeared quickly. This is due to the production of antiplatelet antibodies, which shorten the lifespan of platelets.

Therefore, it is very possible that platelets decrease after transfusion, but this problem can be solved by transfusing fresh blood or plasma.

The Department of Hematology of Ping'an Hospital Affiliated to Hebei Medical University is a national key clinical specialty of the Ministry of Health, with strong expert skills and rich clinical experience. If you need help from a hematologist or want to know more, you can consult with a hematologist for free, or you can call 400-0387-184.

Causes of thrombocytopenia.

Decreased or ineffective platelet production dies:

Excessive platelet destruction.

3) Excessive retention of platelets in the spleen: most commonly in hypersplenism.

Refer to my space.