Is acetaminophen toxic?

This product is the metabolic production of phenacetin in the body, and its inhibition of prostaglandin synthesis in the central nervous system is similar to that of aspirin, but the inhibition of peripheral prostaglandin synthesis is weak, so the antipyretic and analgesic effect is strong, the anti-rheumatic effect is weak, and it has no effect on the platelet coagulation mechanism. Oral absorption is rapid, complete, evenly distributed in body fluids, most of it is metabolized in the liver, intermediate metabolites are toxic to the liver, excreted in the form of glucuronic acid conjugates or from the kidneys, and the half-life is generally 1-4 hours. 【Precautions】 1

Adverse effects are rare and do not cause gastrointestinal bleeding. 2.It can cause nausea, vomiting, sweating, abdominal pain and pallor.

3.Excessive doses can cause liver damage, and in severe cases, coma and even death. If possible, the blood concentration of this product can be measured to understand the degree of liver damage.

4.Children under the age of age and newborns should avoid use due to liver and kidney dysplasia.

Trouble, thanks!

That's right. There is little difference between the safe dose and the toxic dose of painkillers containing this ingredient.

Acetaminophen , chemically known as N-acetaminophen, is a widely used over-the-counter analgesic (pain reliever) and antipyretic (fever-reducer).

The main ingredient of tylenol.

The difference between the safe dose and the toxic dose of painkillers containing this ingredient is very small, and people in the United States die every year because of accidentally taking more than this drug.

Short-term small amounts are not harmful to the body. I remember to eat it after dinner.

Web paraphrasing.

Acetaminophen Elixir: Interpretation: acetaminophen elixir, acetaminophen elixir.

Why did you stop using it? What is the harm to the body?

In the United States, more than 300 people die every year due to swallowing tylenol, the cause is also related to alcohol, the main ingredient in tylenol is acetominophin, about 5% of it will remain in the liver each time, it takes 72 hours to excrete, if we eat every six hours, then most of acetominophin can be discharged, but once you drink, the toxin can not be discharged, its toxicity increases exponentially, if you drink too much alcohol, alcohol fills the whole body, then acetominophin is 100% left in the body, just like a person who does not have alcohol in the body, swallowing the power of twenty tylenol in one go, so that 100% of the toxins left in the body, even if you eat one a day, by the third day, you may be poisoned and die. Alcohol will obviously affect the function of the liver, especially for those with hepatitis B, alcohol and headache medicine must not be touched.

So, don't drink alcohol after taking this medicine.

I just talked about this medicine in class, and the difference between the safe dose of this medicine and the toxic dose is very small, so you must take the medicine according to the instructions and not overdose.