How to test for ALK positive NSCLC?

Updated on healthy 2024-05-17
4 answers
  1. Anonymous users2024-02-10

    According to the pathological characteristics of cancer cells in lung cancer tissues, non-small cell lung cancer (NSCLC) accounts for about 85%, and small cell lung cancer (SCLC): accounts for about 15%.

    For advanced non-small cell lung cancer, testing for ALK fusion genes or ALK fusion proteins is routinely recommended for all patients with adenocarcinoma or NSCLC components that contain adenocarcinoma components. ALK testing is also recommended for patients with small biopsy specimens or non-smoking squamous cell carcinoma. In 2009, Shaw et al. classified ALK rearrangement-positive lung cancer as a specific molecular subtype of non-small cell lung cancer.

    ALK-fusion NSCLC is not only a change in the gene sequence, but also an important variant in ALK-fusion proteins, so such diseases are collectively referred to as "ALK-positive NSCLC". ALK-positive non-small cell lung cancer (NSCLC) is a type of lung cancer with well-defined driver genes. This type of non-small cell lung cancer is highly sensitive to ALK inhibitors, a new type of targeted drug.

    The positive rate of ALK in non-small cell lung cancer in China is 3-11%, and the number of new cases is about 35,000 per year. For ALK-positive non-small cell lung cancer that is positive for gene mutations, targeting** has undoubtedly become a better choice for them**.

  2. Anonymous users2024-02-09

    This must be checked out at the hospital.

  3. Anonymous users2024-02-08

    Check it out.

  4. Anonymous users2024-02-07

    According to the pathological characteristics of cancer cells in lung cancer tissues, non-small cell lung cancer (NSCLC) accounts for about 85%, and small cell lung cancer (SCLC): accounts for about 15%.

    For advanced non-small cell lung cancer, testing for ALK fusion genes or ALK fusion proteins is routinely recommended for all patients with adenocarcinoma or NSCLC components that contain adenocarcinoma components.

    ALK gene testing is also recommended for patients with small biopsy specimens or squamous cell carcinoma who do not smoke. In 2009, Shaw et al. classified ALK rearrangement-positive lung cancer as a specific molecular subtype of non-small cell lung cancer.

    ALK-fusion NSCLC is not only a change in the gene sequence, but also an important variant in ALK-fusion proteins, so such diseases are collectively referred to as "ALK-positive NSCLC".

    ALK-positive non-small cell lung cancer (NSCLC) is a type of lung cancer with well-defined driver genes. This type of non-small cell lung cancer is highly sensitive to ALK inhibitors, a new type of targeted drug.

    The positive rate of ALK in non-small cell lung cancer in China is 3-11%, and the number of new cases is about 35,000 per year. For ALK-positive non-small cell lung cancer that is positive for gene mutations, targeting** has undoubtedly become a better choice for them**.

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