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Hello, thank you very much for your trust in me, PDT photodynamic palliation of esophageal cancer is very good, but there is no way to control cancer cell metastasis, PDT for surgery, photodynamic laser scanning can be carried out during the operation, so that the operation is more thorough, the cancer cells are cleaner, and it plays a very good role in preventing ** and metastasis. Surgery for esophageal cancer greatly increases the probability of metastasis. In fact, chemotherapy can at most play a role in preventing metastasis, once metastasis is found, the use of chemotherapy is more harmful than good.
The best plan for the early detection of esophageal cancer should be PDT photodynamic + chemotherapy, and the condition should be closely observed, because the tumor cannot be operated on without control, and the consequences of surgery are irreversible. If the tumor is well controlled, no surgery is required at all, and the best effect of PDT is better than surgery, and the advantages are very obvious.
Now that the patient has metastasized, and it is confirmed that there is metastasis in the right hip bone, I think there must be more than one place, but it has not been found yet, given that chemotherapy has been done, if it is well controlled, the tumor found can be operated on**, and the ** of PDT is not suitable now.
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It should be okay to eat Nexavar, but it is very expensive, and if you have money, it is recommended to eat Nexavar,
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Chemotherapy is large, and Chinese herbal medicine can be used.
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Experts from the Second Hospital of the Beijing Armed Police Force introduced the ways of esophageal cancer metastasis: 1Intramural diffusion:
It first appears in the esophageal mucosa or submucosa, because of the abundant lymphatic vessels in the esophageal mucosa and submucosa, the cancer can infiltrate the lymphatic vessels along the esophageal lamina propria or submucosa, and the surface is pale or small nodules form. Most submucosal spreads are unremarkable to the naked eye and can only be confirmed by microscopic examination. Nodules that spread along the lymph resemble a second primary cancer, and this type of dispersal within the wall of the esophagus can sometimes be 5 to 6 cm from the primary lesion, so it is important to have an appropriate length of surgical resection.
2.Direct invasion of adjacent organs: Upper esophageal carcinoma can invade the soft tissues of the larynx, trachea and neck, and even invade the bronchi, forming a bronchial fistula; It can also invade the thoracic duct, azygous vein, hilum and lung tissue, and some can invade the aorta to form an esophageal-aortic fistula, causing massive hemorrhage; Lower esophageal cancer often affects the cardia and pericardium.
3.Lymphatic metastases: This type of metastasis is relatively common, accounting for about 2 3 cases.
Mid-segment esophageal cancer often metastasizes to paraesophageal or hilar lymph nodes, but can also metastasize to the neck, pericardia, and left gastric paraarterial lymph nodes; Lower esophageal cancer often metastasizes to lymph nodes such as paraesophageal, paracardia, left gastric artery, and abdominal cavity, and occasionally to the upper mediastinum and cervical lymph nodes. The lymphatic metastases are septum, abdomen, trachea and paratrachea, hilum and parabronchi.
4.Hematogenous metastasis: It is more common in patients with advanced disease, and the most common metastases are liver (about 1 4) and lung (about 1 5), and other organs are bone, kidney, adrenal gland, pleura, omentum, pancreas, heart, lung, thyroid and brain.
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Understanding the ways of esophageal cancer metastasis can enable esophageal cancer patients to make targeted esophageal cancer work when the disease metastasizes, reduce the harm caused by esophageal cancer to patients, and help patients recover as soon as possible.
Esophageal cancer, especially advanced patients, is more likely to metastasize and spread. If the metastasis is not detected in time, the patient's body will suffer more pain. The more common metastases include lung metastases, liver metastases, bone metastases, etc.
Symptoms of metastasis of esophageal cancer are one of the leading causes of death.
It is hoped that patients with esophageal cancer can find the symptoms of metastasis in time and take the first measures as soon as possible.
The pathways of esophageal cancer metastasis are as follows:
1. Direct dissemination and infiltration in the esophageal wall, the earliest appearance in the esophageal mucosa layer or submucosa, because the esophageal mucosa and submucosa in the rich lymphatic vessels, can infiltrate along the esophageal membrane propria or submucosal lymphatic vessels, and the surface is pale or small nodules formed. Most submucosal spreads are unremarkable to the naked eye and can only be confirmed by microscopic examination. Nodules that spread along the lymph resemble a second primary cancer, and this type of dispersal within the wall of the esophagus can sometimes be 5 to 6 cm from the primary lesion, so it is important to have an appropriate length of surgical resection.
Because the esophagus does not have a serous layer, tumors that involve the muscular layer of the esophagus can easily penetrate through loose connective tissue and directly infiltrate adjacent organs. Depending on the location, it affects different organs. Upper esophageal cancer can invade the bronchi to form esophageal tracheal fistula, and can also invade the thoracic duct, azygous vein, and hilum of the lungs.
In a few cases, the cancer tissue invaded the aortic arch to form an aortic fistula, resulting in massive bleeding and death. Lower esophageal cancer can invade the pericardium, diaphragm, cardia, and left lobe of the liver. The elastic membrane of the aorta and the mucosa of the vertebral body have a certain resistance to infiltration. It is generally believed that there is more direct spread in the upper segment and less in the lower segment.
2. Lymph node metastasis of the esophagus is more common, and it is generally believed that the lymph node metastasis of esophageal poorly differentiated squamous cell carcinoma or undifferentiated carcinoma is earlier, and the metastasis site is related to the direction of esophageal lymphatic drainage, and the upper esophageal cancer can invade the paraesophageal, postlaryngeal, deep neck and supraclavicular lymph nodes. Mid-segment esophageal cancer often metastasizes to paraesophageal or hilar lymph nodes, and can also metastasize up or down.
3. Hematogenous metastasis of esophageal cancer is less common, mostly occurs in advanced cases, esophageal cancer metastasis sites are liver, lung, bone, kidney, adrenal gland, pleura, etc., liver and lung are more common, in the autopsy data 1 3 patients of the esophageal local lesions are always more limited, due to local complications obstruction, tracheal fistula, hemorrhage, cachexia and other deaths, so esophageal cancer patients can get good results after comprehensive **.
The above is an introduction to the metastatic route of esophageal cancer, I hope it will be helpful to you. Esophageal cancer patients should not be too anxious after metastasis symptoms, do a good job in dietary care, appropriate changes in living habits, and actively cooperate with doctors, which can effectively improve esophageal cancer.
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There are only a few ways to metastasize almost any kind of cancer: lymphatic metastasis; hematogenous metastases; Planting transfer and direct diffusion.
The same goes for esophageal cancer.
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After many patients with esophageal cancer are diagnosed, they are already in the middle and advanced stages, and most of the cancer cells have spread widely. The main organs of esophageal cancer metastasis are as follows. Liver esophageal cancer accounts for 5%-8% of liver metastases, and the liver metastasis of esophageal cancer is hematogenous metastasis through the portal vein, forming multiple nodular metastases in the liver.
Among the organ metastases of esophageal cancer, liver metastasis occupies the first place. Patients with esophageal cancer liver metastases often have loss of appetite, weight loss, liver enlargement, epigastric mass, and sometimes jaundice, and most of them have no obvious liver dysfunction. Epigastric mass, hepatomegaly, and jaundice are all late manifestations.
Lung Lung metastasis is the second most important metastasis of esophageal cancer, second only to liver metastasis, and the metastasis is mainly hematogenous. Hepatocytes enter the portal vein, pass through the liver and then reach the lungs, so most patients with lung metastases are accompanied by liver metastases. Esophageal cancer lung metastasis forms multiple metastatic nodules in the lungs, the effect is not good, and most of them are at an advanced stage when diagnosed, so it is no longer suitable for surgery.
Peritoneal Esophageal cancer metastases are mostly advanced esophageal cancers that cross the serosa, especially poorly differentiated adenocarcinomas. It is more common in early esophageal cancer, but there are also peritoneal metastases that occur more than ten years after surgery. Ascites is often associated with peritoneal metastasis of esophageal cancer, and it can also infiltrate the intestines, ureters, and common bile ducts, causing adhesions, causing narrowing of the intestines, common bile ducts, and ureters, forming various degrees of obstruction, and a mass can be found in the abdomen.
The brain is mostly manifested as increased intracranial pressure, which is mainly caused by the rapid growth of tumors and severe surrounding edema, and the symptoms of increased internal pressure are more significant, resulting in headache, nausea and vomiting, and decreased vision. Local symptoms may include limb numbness or weakness, hemiplegia, hemianopia, aphasia, localized convulsions, ataxia, etc. The typical symptoms of bone metastasis of bone and esophageal cancer are progressive local bone pain, percussion pain, mostly accompanied by anemia, fever, hemorrhage, and a few may have local masses or complicated rational fractures.
Typical x-rays often show lytic bone destruction. Moreover, bone metastases of esophageal cancer are more common in general, and single bone metastases are rare.
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Hello, esophageal cancer liver metastasis accounts for 5%-8%, and the liver metastasis of esophageal cancer is hematogenous metastasis through the portal vein, forming multiple nodular metastases in the liver. Among the organ metastases of esophageal cancer, liver metastasis occupies the first place.
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For advanced cancer pain, analgesic drugs can be considered. There are many types of painkillers, and you can choose according to the situation.
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Chemotherapy may be used, or low-dose radiation therapy to metastasize bone can be used to reduce pain, and painkillers such as tramadol may be used. Consult your doctor for specific application methods.
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