What is transamase and how does it fluctuate

Transanase is an indicator of liver function, drinking alcohol and eating will have an impact, if it is seriously high, it may be a problem with liver function

Harmful aminotransferases mainly exist in hepatocytes, including alanine aminotransferase and aspartate aminotransferase, when hepatocytes are inflamed and necrosis, transaminases are released into the middle, which will cause the concentration of transaminases to rise. Thus, high aminotransferases generally indicate liver damage. High aminotransferases are common in patients with liver disease, and the harm of high aminotransferases varies among different patients with liver disease.

If aminotransferases are elevated due to viral hepatitis (eg, hepatitis B, hepatitis A, hepatitis C, etc.), high aminotransferases at this time often indicate inflammatory activity in the liver, accompanied by liver damage, and require early antiviral treatment**. If the aminotransferase is too high and not received in time**, it may lead to continuous damage to the liver, and then form cirrhosis. In China, patients with viral hepatitis are most harmed by high levels of aminotransferases.

If the aminotransferases are elevated due to cirrhosis or liver cancer, it means that the patient's condition is deteriorating or unstable, and liver cirrhosis and liver cancer are prone to complications, which may be life-threatening if not timed**.

If the aminotransferases are elevated due to alcoholic liver and fatty liver, if the liver is not carried out, it will also lead to continuous damage to the liver and eventually form cirrhosis and liver cancer.

It means that the liver has been damaged and you need to pay attention not to drink, not to stay up late, and not to overwork. Otherwise, this will lead to cirrhosis and eventually liver cancer in the long run. Hope to adopt.

Aminotransferases are an indicator of liver function and are often done during a physical examination.

Aminotransferases are essential "catalysts" in the body's metabolic processes and are mainly found in liver cells. When liver cells are damaged, such as inflammation, necrosis, poisoning, etc., transaminases will be released into the blood, resulting in an increase in serum aminotransferases.

Usually, the main aminotransferase to be checked in a physical exam is alanine aminotransferase (ALT). 1% liver cell damage can increase the concentration of ALT in the blood by a factor of 1. Therefore, ALT levels can be more sensitive to detect whether the liver is damaged.

Aminotransferase levels between 0 and 40 are normal. If it is outside of the normal range, the doctor will recommend another test to rule out the possibility of errors due to factors such as malfunction of laboratory equipment and operating errors. If aminotransferase levels are high, they are most likely due to viral hepatitis or other liver diseases.

However, to determine whether it is viral hepatitis, other tests are needed, combined with a comprehensive analysis of medical history, symptoms, and signs.

Even if viral hepatitis is confirmed, the degree of ALT elevation cannot be judged simply because in severe hepatitis, there may be fewer surviving liver cells and few aminotransferases released into the bloodstream, and ALT decreases as the disease worsens.

High aminotransferases are not always hepatitis.

An elevated ALT simply indicates that the liver may have been damaged. In addition to hepatitis, many other diseases can cause elevated aminotransferases. Professor Wang pointed out that there are mainly the following situations:

First, many tissues in the body contain aminotransferases, such as myocarditis and myocardial infarction, which can increase aspartate aminotransferases.

Second, if there is biliary obstructive disease such as gallstones, the level of transaminases in the blood may be elevated due to gall stasis.

In addition, for some people who don't seem to have a serious illness, there is also a possibility that long-term alcohol abuse can lead to alcoholic liver, or unreasonable diet may lead to fatty liver, resulting in high aminotransferases.

Exertion may also elevate aminotransferases.

For healthy people, an increase or decrease in aminotransferase levels within the normal range does not mean that there is something wrong with the liver, because aminotransferases are very sensitive, and aminotransferase levels can fluctuate at different times of the day in healthy people.

In addition, aminotransferase levels in healthy people may temporarily exceed the normal range. Strenuous exercise, overexertion, or a recent history of fatty foods can cause transaminases to be temporarily high. If you work overtime the night before the transaminase test, don't get a good night's sleep, or eat fried food for breakfast before the exam, the test results may be out of the normal range.

A person who has just run a few laps on the playground immediately has his aminotransferase levels checked, and the results may also be higher than normal.

If the aminotransferase level is elevated due to these conditions, just rest well and check it again after a while, and you will find that the aminotransferase level has returned to normal.

Another condition that can cause an increase in aminotransferases is to take drugs that can damage the liver when you are sick, such as erythromycin, tetracycline, sleeping pills, antipyretic analgesics, contraceptive pills, and traditional Chinese medicines such as banxia, betel nut, and green daisy. After these drugs are stopped, aminotransferase levels return to normal very quickly.

Analysis: Hello friend! There are many reasons for the elevation of aminotransferases, such as viral liver disease, alcoholic liver disease, toxic liver disease, drug-induced liver disease, autoimmune liver disease, fatigue, hepatitis, diet, guidance: drugs, etc. may cause the elevation of aminotransferases.

Common causes of elevated transamase are:

Diseases of the liver itself, especially various types of viral hepatitis, cirrhosis, liver tuberculosis, liver cysts, liver cancer, fatty liver, Wilson's disease, etc., can cause varying degrees of transamase elevation.

In addition to the liver, other organs and tissues in the body also contain this enzyme, so when myocarditis, pyelonephritis, lobar pneumonia, tuberculosis, Japanese encephalitis, polymyositis, acute sepsis, enteric typhoid, encephalitis, malaria, cholecystitis, leptospirosis, influenza, measles, schistosomiasis, crush syndrome, etc., blood transaming enzymes can also be seen.

Because transamase is excreted from the bile ducts, if there are diseases of the bile ducts, gallbladder and pancreas, and bile duct obstruction, transamase can also be elevated;

Drug-induced or toxic liver damage, as well as drug allergies, can cause elevated transaminase, which can be accompanied by cholestatic jaundice and hepatocellular injury;

Normal pregnancy, pregnancy toxins, and acute fatty liver of pregnancy are also common causes of elevated transamenzymes. In addition, strenuous exercise can also cause an increase in transamase.

Therefore, it is recommended that you go to a regular hospital for diagnosis.

Non-pathological causes:

For example, strenuous exercise, overwork, or eating greasy food before the examination, taking certain medicines, etc., may cause mild high aminotransferases. There are many pathological causes, and the common causes of high aminotransferases are:

1. Viral hepatitis is a common disease that causes high aminotransferases, and other types of hepatitis can also lead to high aminotransferases.

2. A variety of drugs and chemical agents can cause high aminotransferases, but they can return to normal after stopping the drug.

3. Heavy or long-term drinkers with high transaminases.

4. When liver cirrhosis and liver cancer cirrhosis are active, high aminotransferases generally occur.