Can children born to children of epilepsy patients develop epilepsy and genetics?

From a genetic point of view, there are three types of epilepsy: one is definitely not hereditary; the second is genetically predisposed; The third is definitely hereditary.

The vast majority of epilepsy is not inherited, i.e., most epilepsy is acquired after birth; The prevalence of epilepsy in the offspring of patients with genetic predisposition is 3 to 4 times higher than that of the general population, and the risk is about the same in the general population; Epilepsy that is definitely inherited is generally symptomatic epilepsy, which means that this epilepsy is more of a manifestation of a genetic disorder, rather than a simple epilepsy.

In general, the offspring of people with epilepsy are at higher risk of developing epilepsy than the general population. But it's hard to know for sure when it comes to a specific person. It should be considered in combination with the patient's family history, seizure type, age of onset, and EEG characteristics.

Patients with epilepsy have a significantly increased risk of developing epilepsy in their offspring: female patients; The patient's father or mother has epilepsy; The patient has a young age of onset, especially before the age of 10 years; The patient's lover has epilepsy. That is, both husband and wife are epilepsy patients, and the risk of epilepsy in their offspring is 6; Patients with multi-spike waves and spike and slow complex waves on the EEG.

Mine may not fully meet your requirements, hope it will be useful to you.

When it comes to the inheritance of epilepsy, different types of epilepsy can be inherited in different ways. According to research, many types of epilepsy are polygenic inheritance, and seizures are either a symptom of a monogenic inherited disease, or autosomal dominant inheritance, and people in the upper and lower generations of immediate family members suffer from epilepsy; Autosomal recessive inheritance, no epilepsy in both parents, but cases in the previous generation; There is also x-linked recessive inheritance, in which women are carriers and do not develop the disease, but children may develop the disease after marriage. In short, the genetic research of epilepsy has confirmed that the essence of heredity is genetic defects, but the genetic defect sites of various types of epilepsy are at the **, what is the mode of action of genes, and it is hoped that there will be further breakthrough discoveries in the future.

Getting married and having children is a great thing, but for newlyweds with epilepsy, it is a problem, will epilepsy be passed on to the next generation? This is something that many people want to know. Let's ask an expert to introduce it to us.

In general, if the parent has epilepsy, the chance of the child developing epilepsy is slightly higher than in the normal population. However, whether a child will have epilepsy depends mainly on the type of epilepsy** and the type of epilepsy that the parent has or has. If a father's or mother's epilepsy is still not found after a detailed examination, their child is more likely to develop epilepsy.

Moreover, the genetic factors of pediatric epilepsy depend on the mother of the child, and if a pregnant woman has epilepsy, the risk of various malformations in babies born to women who take antiepileptic drugs during pregnancy is 2 to 3 times higher than that of the normal population. Therefore, women with epilepsy should be mentally prepared when they are pregnant or before they become pregnant, and they should discuss it with their doctor first, so that they can have a prior understanding of whether their child will have epilepsy.

Is there a relationship between genetic disorders and the occurrence of epilepsy?

Pediatric epilepsy is affected by genetic factors, and it can be seen that some genetic diseases are related to the occurrence of epilepsy. For example, benign familial neonatal seizures, benign familial infantile seizures, juvenile myoclonic epilepsy, autosomal dominant nocturnal frontal lobe epilepsy, and adolescent progressive myoclonic epilepsy are all caused by "epilepsy genes". Similarly, some hereditary diseases may cause epilepsy if they invade the central nervous system, most of which are inherited metabolic diseases.

Inherited metabolic disorders include amino acid and organic acid metabolism, urea cycle metabolism (hyperammonemia), vitamin B. deficiency, peroxidosis, mitochondrial disease, etc. Amino acid metabolism disorders are:

phenylketonuria, classic maple syrupuria, isovaleric acidemia, sulfur-containing amino acid metabolism; Organic acid metabolism diseases mainly include propionic acidemia, hyperlactic acidemia, non-ketotic hyperglycemia; Peroxidism includes adrenoleukodystrophy and Zellweger's disease. Inherited metabolic disorders tend to begin in the neonatal period and in infancy and early childhood, so unexplained seizures at this age should be alerted.

There is a high probability of epilepsy. Because epilepsy is genetically related, the prevalence of idiopathic epilepsy in relatives is about 19%-35%, which is significantly higher than the incidence of symptomatic epilepsy, and the prevalence of relatives with symptomatic epilepsy is higher than that of the general population, that is, the closer the blood relationship with the patient, the higher the hereditary probability.

The heritability of epilepsy is not very certain because every person with epilepsy has a different condition and genetics. People with epilepsy who want to have children are reminded that it is best to regenerate after the epilepsy is well controlled, so that the chances of inheriting the tradition are low. Epilepsy has a genetic predisposition, but the impact on the next generation is not 100%.

In general, only 5% of children with epilepsy have epilepsy, so people with epilepsy can have children.

According to the data, more than 90% of the children born to epilepsy mothers are healthy, so the children they give birth to are likely not to have epilepsy.

Pediatric epilepsy is hereditary, so when preparing for pregnancy, it is necessary to take relevant preventive measures.

Yes, if the condition of this disease is not stopped in time, there will really be a genetic condition, and any symptoms of the disease need to be checked in advance.

This condition is really hereditary, so we must check it clearly when we check the child, and we must do a good test for the fetus when we are pregnant, so that we can avoid this problem.

Hello! It is recommended that mothers give birth to boys.

Epilepsy is hereditary, but not 100%, and it is related to ** and gender. Female epilepsy is higher than male epilepsy, and primary epilepsy (congenital inheritance) is higher than secondary epilepsy (acquired effects). In general, only 5% of children of people with epilepsy have epilepsy, so people with epilepsy can have children.

However, from a eugenic point of view, it is best for patients with epilepsy to avoid marrying people with low convulsive thresholds (including epilepsy patients and epileptic messengers), and patients with epilepsy should have children after their condition is stable and their seizures are basically controlled. In addition, the effects on the fetus mainly come from the mother, and the father with epilepsy is generally not inherited.

Eat more nutritious, easy-to-digest foods such as pasta, legumes, lean meat, eggs, fish, milk, etc.

Participate in moderate sports, such as walking, jogging, badminton, tennis, table tennis, etc., do not participate in swimming, mountaineering, diving and other sports, and try not to ride a bicycle to prevent falling injuries or traffic accidents.

Hope it helps, hope!

Epilepsy has a genetic bias, and many people know that female epilepsy patients have their own worries about passing on epilepsy to the next generation, so they dare not get married and have children. Let's take a look at the specific introduction of experts from Guangzhou Epilepsy Hospital. Recommended reading: How to take care of people with epilepsy.

A large number of studies have shown that the incidence of epilepsy is not particularly large, and the family members of patients do not need to worry too much about whether epilepsy will be passed on from generation to generation. It is well known that epilepsy has a genetic bias, but it only explains that people with genetic predisposition have a low outbreak threshold and a high degree of susceptibility to infection, and it is easy to have an epilepsy outbreak when encountering certain conditions, but the onset is determined by both internal and external factors. Genetic outbreaks of epilepsy outside of real life account for only a small fraction of all epilepsy.

According to experts, only specific elements of epilepsy will form the inheritance of epilepsy, and the common genetic elements are: epilepsy is a rare mental disease, whether it occurs at various ages, it may not be hereditary, but the probability of heredity is very small.

After the analysis of the above experts, we can know that the genetic probability of epilepsy is small, and the probability of the father inheriting epilepsy to his child is extremely low, and the master does not need to worry about it. Epilepsy is very harmful, if someone is found to have suspected symptoms of epilepsy, they should go to a regular hospital as soon as possible to receive a diagnosis and understand the best symptomatic treatment. For more details, please click to consult the ** experts of our hospital, I wish you a speedy recovery!

Epilepsy is not a hereditary disorder, so it is not hereditary. From the point of view of the onset of epilepsy, epilepsy is divided into two types, one is primary epilepsy and the other is secondary epilepsy. Primary epilepsy is mainly due to the fact that there may be some small defects in the brain during development, which leads to some neuronal disorders of the cranial nerves, or small lesions of some brains, which cause abnormal electrical discharges in the brain to cause seizures.

Secondary epilepsy is mainly secondary to various cerebrovascular diseases, brain tumors, encephalitis, and sequelae of traumatic brain injury. Therefore, it can be seen from these ** that the onset of epilepsy is not a genetic process, so the father with epilepsy is generally not passed on to the next generation.

Questions. The child suddenly shuddered or trembled, and then squinted for a while. Isn't that the case?

Hello, according to your description, the child is likely to be caused by epilepsy ** and the pathogenesis is complex, prevention is more difficult at the same time about 70% of the current epilepsy patients ** unknown, and the prevention is impossible and a considerable part of symptomatic epilepsy, although the cause is clear, prevention is also difficult, such as brain tumors, arteriovenous malformations and other simultaneous seizures are the result of a multi-factor comprehensive action, including at least convulsive threshold (related to genetic factors), neurological lesions and predisposing factors** The best method for pediatric epilepsy is neurokine implantation.

But this is not inherited.

Questions. **The best hospital for this disease**? Can you tell us about it?

Okay, what city are you in?

In the past 40 years, many domestic and foreign research materials have confirmed that epilepsy does have a genetic predisposition.

Someone surveyed the relatives of more than 3,000 epilepsy patients and found that the closer the blood relationship, the higher the prevalence, and the prevalence of epilepsy in the general population is about; The prevalence among siblings of epilepsy patients is that of parents, uncles, uncles, and aunts, grandparents, and cousins.

Judging whether epilepsy will be inherited can be judged from two aspects, the most direct is to look at the family history, investigate whether there is epilepsy in the paternal or maternal family members of three to four generations, generally if it is hereditary epilepsy, at least two or three or more family members will be sick, but to exclude acquired epilepsy members, such as cerebral hemorrhage, brain trauma, brain tumor, etc. In addition, to judge whether epilepsy is inherited, it can be judged from the perspective of genetics, and now medicine has found some epilepsy-related genes, if similar genes are found, then there is a certain probability of inheritance, but even if there is a problem with the gene, it is not 100% that there will be epilepsy, some are recessive inheritance, and some are dominant inheritance.

At present, the hereditary epilepsy found mainly includes febrile seizures, some benign epilepsy in infants and young children, and tuberous sclerosis. Although it is hereditary, such as tuberous sclerosis, parents can have nodules without developing the disease, and some patients are not inherited, but the result of their own genetic mutations.

In addition, there is a more objective phenomenon that most of hereditary epilepsy is benign, that is, it only occurs in infancy and early childhood, and it is fine or rarely has seizures in adulthood, and it does not affect intelligence, and can study, work, and have children like a normal person, because only in this way will his epilepsy gene be inherited and passed on from generation to generation. The more severe epilepsy, frequent seizures, mental retardation, and inability to study, work, and socialize are either due to premature death due to illness, or because they are unable to marry and have children, so that the epilepsy gene is eliminated.

Hello, if the parents are epilepsy, well, can I have a child? This has to be done in the hospital. Doctor's instructions and doctor's.

If this is arranged, it should also be possible to prepare for pregnancy and have a child. Because it may be possible to give your child vaccinations in advance, etc., it may be possible, so you must go to the hospital for a check-up in advance.