Do I have to have chemotherapy before a bone marrow transplant? How long does it take to transplant

Before transplantation, it is generally a high-dose chemotherapy to kill all the hematopoietic cells in the body as much as possible, so that the transplanted stem cells can be better converted into hematopoietic cells. Chemotherapy suffers, the risk of transplantation is not generally high, except for big cities such as Beijing and Shanghai, there are not many transplants in China that have survived for 5 years after transplantation.

Chemotherapy is to reduce rejection) Although bone marrow transplantation is the most advanced method in the international medical community, and even advertised as the first method of leukemia, it is actually the most cruel and domineering**, which will leave the most traumatic page in the history of international medicine.

Chemotherapy is done to reduce rejection. How often to ask the attending physician.

In the case of bone marrow transplants, bone marrow transplant patients spend at least 20 days to 1 month in a sterile warehouse. At first, you may not be able to eat, you can only infuse high protein, and all the meals you eat will be sterilized before entering the warehouse. About 3 weeks after the bone marrow transfusion, it is very dangerous to grow new bone marrow in the body, and I am afraid of infection or other symptoms.

Because the patient has no resistance, the white blood cells have not grown normally, and it has only been about 1 month. Of course, some patients may have white blood cells that can rise to more than 1,000 at 20 days before they can be transferred from the sterile warehouse to the general ward for observation. If the patient is doing well, he or she will be discharged quickly.

However, after being discharged from the hospital, it is necessary to take rejection drugs for a long time**, and only after the rejection period has passed can the patient's resistance be enhanced.

Surgery is complex, in which the following questions are addressed.

1. Suitable bone marrow.

2. Perioperative period.

3. The operation period is long, and whether the patient's physical fitness can keep up is generally about a month, and there must be a lot of immune drugs injected every day.

4. After postoperative discharge, whether the use of immunosuppressants is appropriate, and there is no rejection or host reaction.

5. Pay attention not to get infected after surgery.

If these problems are solved, it will not be a big problem in 10 or 8 years. It cannot be said that the risk of organ transplantation is still very large, and rejection and infection will occur at any time, which will lose the transplant results and kill you. In addition, bone marrow transplantation also has a host response, which is also a key follow-up.

After the bone marrow transplant survives, it is just like a normal person. Allogeneic bone marrow transplantation (ALLO-BMT) is the first method to implant hematopoietic stem cells in healthy bone marrow into the patient's body after ultra-high-dose radiotherapy and chemotherapy pretreatment, so that his hematopoietic and immune function can be rebuilt.

The use of bone marrow ** disease began in 1891 when Brown-Sequard gave patients oral bone marrow ** anemia, in 1939 Osgood first intravenous infusion of bone marrow, in 1951 Lorenz et al. first successfully carried out bone marrow transplantation trials, in the 70s of the 20th century, the development of HLA tissue matching technology, transplant immunology and other basic medical research in-depth, so that the clinical application of BMT has been rapidly developed, and a number of BTM centers have been established around the world. In recent years, there have been more than 300 cases of allogeneic BMT in China, and the efficacy has basically reached the same level in the world.

Chemistry can be divided into 2 main phases, i.e., induction of remission** and post-remission**. The goal of remission induction** is to stabilize the condition to the criteria for complete remission. The so-called complete remission, that is, the disappearance of signs and symptoms of leukemia, HB 100 g L (male) or 90 g L (female and children), absolute neutrophil value, platelets 100 109 L, no leukemia cells in the peripheral blood leukocyte differential; Bone marrow icon:

Progranulocytes + promyelocytes (promonocytes + promyelocytes or prolymphocytes + lymphocytes) 5%, erythrocytes and megakaryocytes are normal.

Envy years old .21174677"..0...Xiankai.

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You need to ask your doctor.