What are the symptoms of Epstein Barr virus, what are the symptoms of Epstein Barr virus infection,

1. Fever: Fever for more than 1 week, heat peak'c。

2. Hepatosplenomegaly: hepatosplenomegaly with pancytopenia, cumulative" = 2 cell lines.

3. Cytopenia (peripheral blood bilineage or blood lineage cytopenia), including hemoglobin < 90g L, platelet < 100x109 L, neutrophils <.

4. Hypertriglyceridemia and/or hypofibrinogenemia.

5. Hemophagocytes can be seen in bone marrow, spleen or lymph nodes but no malignant manifestations.

6. Decreased or lack of NK cell activity.

7. The level of soluble interleukin-2receptor (SIL-2R) in ferritinemia is increased.

1Epstein-Barr virus infection, except for very mild, all have fever symptoms, body temperature generally varies at degrees Celsius, can be relaxant fever, irregular fever or residual fever, the heat type is not fixed, and the fever duration can vary from days to weeks. The longest fever can last up to 2 to 4 months. Fever may be accompanied by chills and chills.

The fever may subside or subside abruptly, with sweating.

2. 70% of patients with mononucleosis caused by EB virus infection have obvious lymphadenopathy, which can appear in the first week of the course of the disease, and superficial lymph nodes are generally affected, with cervical lymph nodes being the most common, followed by axillary and inguinal lymph nodes, and occasionally accumulation of thoracic, mediastinal and mesenteric lymph nodes. Diameter 1 4 cm, medium hardness, dispersed without adhesion, no obvious tenderness, non-suppuration, asymmetrical on both sides.

About half of patients with 3EB virus infection have congested and swollen pharynx, tonsils, and uvula, and a few have ulcers or pseudomembrane formation, accompanied by sore throat, and severe swelling may cause dyspnea or dysphagia.

About 15% of patients infected with 4EB virus will have hepatomegaly, mostly within 2 cm below the cost, with tenderness and percussion. About 2 to 3 patients will have abnormal liver function, alanine aminotransferase will be elevated, and some patients will develop jaundice. About half of patients have mild splenomegaly, which is most pronounced in the second week of the course of the disease, and after 7 to 10 days, it can gradually shrink, and splenomegaly is painful and tender, and occasionally a mega split spleen rupture.

About 10% to 30% of patients infected with 5EB virus will develop a rash that is polymorphic, with scarlet fever-like rash, maculopapular rash, urticaria, erythema nodosum, etc., and occasionally hemorrhagic ones. The rash is more common on the trunk and appears within 7 to 14 days after the onset of EBV infection and resolves within 1 week without obvious traces. A typical mucosal rash can be seen, seen in the middle of the junction of the soft and hard palate, and is manifested as multiple pinpoint-like petechiae.

Encephalitis can occur after 6EB virus infection, causing symptoms such as fever, headache, body pain, nausea, vomiting, fatigue, and a few symptoms such as myocarditis. Or it is known that there may also be more serious symptoms such as consciousness disorders, coma, and convulsions.

7. It is more common to be middle-aged and elderly people over 40 years old. According to the surface, undifferentiated nasopharyngeal carcinoma is associated with Epstein-Barr virus infection. In undifferentiated nasopharyngeal carcinoma, EBV mainly infects nasal mucosal epithelial cells, but the mechanism of its occurrence is not clear.

However, Epstein-Barr virus helps with tumor growth and evades immune surveillance.

It is more common in young people, and a large number of studies have linked surface lymphoma to EBV infection, which is 4 times more common in EBV infection than in healthy people.

It is more common in children aged 5 to 12 years, occurs in Central Africa and the Americas, and is more common on the face and palate. Epstein and Barr were also discovered in 1964 from tumor cell culture while studying malignant lymphoma in African children.

The incidence of gastric cancer is high, and more and more studies have been conducted to show that gastric cancer is associated with Epstein-Barr virus infection. Detection of cancer cells showed that EBV was present in gastric lymphoid carcinoma and gastric adenocarcinoma.

1. When the Epstein-Barr virus occurs, except for mild cases, fever will occur, about degrees Celsius, and there is no fixed fever type. Some patients are accompanied by chills, chills, and fever of varying duration, from a few days to several weeks, and some can last up to 2 to 4 months. Fever decreases, and dismantling is accompanied by sweating.

2. 70% of patients with infectious mononucleosis will have lymphadenopathy, which can generally appear in the first week of the course of the disease, and the superficial lymph nodes are generally involved, with cervical lymph nodes being the most common, followed by armpit and groin, and occasionally thoracic, mediastinal and mesenteric lymph nodes can also be involved. 1 4 cm in diameter, medium hardness, dispersed but not adherent, no obvious tenderness, no suppuration, asymmetrical on both sides. Mesenteric lymph node involvement may present with symptoms such as abdominal pain.

3 When EBV attacks, about 2 3 cases may have abnormal liver function, such as elevated alanine aminotransferase (ALT), and some patients will develop jaundice.

At the time of 4EB virus attack, about 10% of patients have hepatic enlargement, usually 2 cm below the costume. Half of the patients have mild splenomegaly, pain and tenderness, and rarely splenic rupture.