What is Parkinson s disease? What causes Parkinson s disease?

Parkinson's disease, also known as parkinsonism, is a progressive central nervous system degenerative disease that occurs in middle and old age. The onset is insidious, with no characteristic symptoms and signs in the early stages, so it is difficult to detect and often overlooked. **It is not clear at this time.

The main symptoms are motor symptoms such as resting tremor, muscle rigidity, bradykinesia, and abnormal posture, and the secondary symptoms include psychiatric symptoms, cognitive dysfunction, sleep disorders, autonomic dysfunction, language disorders and other non-motor symptoms. There is currently no effective method.

Note that it is different from Parkinson's syndrome and Parkinson's superposition syndrome, and Parkinson's syndrome is clear, such as drug-induced, toxic, vascular, traumatic (boxing champion Ali), etc.; Parkinson's superimposed syndrome is a group of neurodegenerative disorders with unidentified multisystem neurodegenerative manifestations and Parkinson's sign as an additional symptom.

Hello! I am Wang Hua from Shanghai, I had surgery with you in August last year, and now I am completely **, I can write to you in person, and I can take care of my own life, thank you very much.

Three years ago, I had tremors in my limbs for no apparent reason, choking on water, and I couldn't take care of myself, which gradually worsened. I became a great burden to my children, and I had the heart to die, but I didn't even have the ability to kill myself.

Later, my daughter found out on the Internet that your hospital can treat Parkinson's, and we went to Weihai with the psychology of treating dead horses as live horse doctors, but I didn't expect this trip to Weihai to change the rest of my life. After the operation, I am getting better and better day by day, and now I can do the fine work myself, a thousand words, can not express my gratitude, a text message to express my heart, I must tell this good way to those who need help.

I wish you all success in your work and a happy life! Wang Hua respectfully.

Parkinson's disease, also known as parkinsonism, is a common disease in middle-aged and elderly people. Its main manifestations are tremor, rigidity, slow-moving, and postural disturbances. Tremor:

It usually starts from one limb, rhythmic shaking, which is more obvious when resting and disappears during sleep. As the disease progresses, tremors may occur in the contralateral limb, jaw, lips, and tongue. Ankylosis:

Stiff limb and trunk muscles, rigid facial expressions, and reduced blinking movements are called "mask faces". Slow movements: various actions in daily life, such as putting on clothes, tying shoes, etc., are slow, the more the words are written, the distance between two steps is reduced, the voice is low, the voice is monotonous, and there may be difficulty swallowing, choking and coughing when eating.

Postural disorders: the head, neck and trunk are tilted forward when the patient stands, and the knee joints are slightly flexed; When walking, the body leans forward and falls easily. Other symptoms may include oil overflow, constipation, depressed mood, and decreased intelligence.

Medical studies suggest that the occurrence of Parkinson's disease is related to the degeneration and death of dopaminergic neurons in the substantia nigra, but what exactly causes the degenerative death of these neurons has not been clear, and it may be related to a variety of factors, including genetic factors, environmental factors, and aging of the nervous system.

What are the best causes of Parkinson's disease?

Genetic factors. It is thought that 10% of patients have a family history, and the vast majority of patients are sporadic.

Environmental factors. Industrial or agricultural toxins in the environment that are similar to the neurotropic 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine (MPTP) molecular structure, such as certain pesticides, herbicides, rotenone, etc., may be one of the most important causes of Parkinson's disease.

Aging of the nervous system.

Some data show that after the age of 30, with age, the substantia nigra dopaminergic neurons begin to show degeneration, but not all of them lead to Parkinson's, aging is the most important factor in the occurrence of Parkinson's disease.

Multi-factor interactions.

Genetic susceptibility increases the likelihood of disease, except for a small number of people with familial Parkinson's disease, except for a small number of people with familial Parkinson's disease, but it does not necessarily lead to the disease.

It will lead to the onset of the disease under the combined action of environmental factors, sensitization of the nervous system and other factors.

Parkinson's is caused by many kinds of spine factors, the common ones are posthumous factors, environmental factors, aging factors, brain neurodegeneration factors, etc., this disease can be combined by drugs ** for the main smiling cherry blossoms, **** and psychological ** supplemented by the method **, but can not be completely**, can only improve the development of the disease, alleviate the patient's symptoms and pain.