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Alanine aminotransferase or aspartate aminotransferase? The increase is due to the destruction of hepatocyte function, which is a manifestation of liver function damage.
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Alanine aminotransferase is found only in liver cells. When there is a problem with the liver cell, such as a decrease in permeability, it can enter the bloodstream. This occurs during a blood test and indicates impaired liver function.
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There is alanine aminotransferase in hepatocytes, and too much alanine aminotransferase in the blood is due to damage to the hepatocytes and the transaminase into the blood, resulting in high transaminases in the blood. This can be caused by alcohol consumption or acute or chronic hepatitis.
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The causes of increased aminotransferases are as follows:
1. Viral infection of hepatocytes: common infections include hepatitis A virus, hepatitis B virus, hepatitis C virus, hepatitis E virus, etc., which lead to damage to liver cells and increase aminotransferases;
2. Drug or food factors: after taking drugs and foods that damage liver cells, it will lead to the destruction of liver cells, and the blood transaminases will be significantly increased.
3. Autoimmune hepatitis: it will cause liver cell damage and increased aminotransferases;
4. Biliary obstructive diseases: common bile duct stones, common bile duct tumors, pancreatic head tumors, and liver tumors lead to bile duct blockage, bile can not be discharged smoothly into the intestinal lumen, and reflux into the blood, resulting in liver cell damage, and the transaminase bilirubin in the blood is significantly increased.
If there is an increase in aminotransferases and bilirubin, it is necessary to go to the hospital for relevant examinations to understand the specific cause and take effective countermeasures.
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Well, there are many reasons for elevated aminotransferases.
1. When liver cirrhosis and liver cancer cirrhosis are active, aminotransferases are higher than normal levels, and they should be active.
2. In the acute attack of cholecystitis and cholelithiasis of biliary tract diseases, fever, abdominal pain, nausea, vomiting, jaundice, elevated blood bilirubin and aminotransferases are common.
3. In the case of acute myocardial infarction, myocarditis and heart failure of heart disease, ALT and AST are both increased, and patients often have chest pain, palpitations, shortness of breath and edema. Cardiac examination has positive signs and an abnormal ECG.
4. Alanine aminotransferase will also rise in large or long-term drinkers.
5. Viral hepatitis is the most common disease that causes elevated aminotransferases, and all kinds of acute and chronic viral hepatitis can cause elevated aminotransferases.
6. All kinds of drugs and chemical preparations for toxic hepatitis can cause the increase of transaminases, but after the drug is stopped, the transaminases can return to normal.
7. Some other infectious diseases, such as pneumonia, typhoid, tuberculosis, infectious mononucleosis, etc., all have elevated aminotransferases, but these diseases have typical symptoms and can be confirmed with the help of laboratory testing. In addition, acute soft tissue damage, strenuous exercise, and pregnancy may also cause transient elevation of aminotransferases.
Therefore, there are many possibilities, if it is only a short period of time, if it is high, there is nothing if it is high, it is a liver problem, but it needs to be symptomatic**, according to ** and treatment.
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What causes high aminotransferases during a physical examination? Acute soft tissue injuries, strenuous exercise, taking medications, drinking alcohol, etc., can also produce transient alanine aminotransferase levels. Other organ diseases, such as biliary tract diseases (cholecystitis, acute attack of cholelithiasis, etc.), heart diseases (acute myocardial infarction, myocarditis, heart failure, etc.), as well as pneumonia, typhoid fever, tuberculosis, etc., will cause different degrees of elevation of aminotransferases.
What is more troublesome is that hepatitis B can also cause high aminotransferases, so you should pay attention! Patients who are antiviral** should be treated with appropriate medications** depending on their condition. At present, there are two types of antiviral drugs for hepatitis B recommended by the state: interferon and nucleoside analogues, of which about ninety percent of hepatitis B patients are using oral nucleoside analogues.
There are four types of nucleoside analogues: lamivudine, adefovir dipivoxil, entecavir and telbivudine. These four drugs also have their own characteristics, such as entecavir represented by Runzhong, which has strong virus inhibition and the lowest drug resistance; The adefovir disodisil represented by Mingzheng is relatively inferior in antiviral, but the drug resistance is excellent, and it can be used for patients who are resistant to the other three drugs, however, what drug to choose for ** also needs to be decided by professional physicians according to the patient's condition. In addition, you must follow the doctor's instructions when taking, changing, and stopping the medicine, and you must not take it for granted.
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Hello, elevated aminotransferases are liver damage, also known as hepatitis, there are many reasons that can lead to elevated aminotransferases, common acute hepatitis, chronic hepatitis, such as viral hepatitis, such as hepatitis A, hepatitis B, hepatitis C, hepatitis D. There are also drug-induced hepatitis, alcoholic hepatitis, steatohepatitis, autoimmune hepatitis, etc., which can not only cause chronic liver damage, but also lead to acute liver cell damage and necrosis. In patients with liver cirrhosis, transaminases can also be elevated, liver cancer can lead to elevated aminotransferases, and bile duct diseases such as cholestasis and biliary obstruction are also prone to high transaminases.
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Hello this friend. There are many reasons for high aminotransferases, which are currently detected by physical examination. Illustrating that the ultrasound of the hepatobiliary is normal, which excludes fatty liver, cirrhosis, and suprahepatic tumors, among others. In addition, hepatitis B and hepatitis C antibodies need to be checked to rule out the possibility of hepatitis B;
Colds, myocarditis and other diseases can also cause high aminotransferases. In addition, long-term rest, poor rest, or excessive alcohol consumption can be caused. It is recommended to exclude them one by one.
If the aminotransferases are too high, it is recommended to lower the enzymes as soon as possible to protect the liver** to restore liver function, and at the same time rest more, avoid alcohol, and strengthen liver nutrition and health care.
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Alcoholic liver disease: The incidence of alcoholic liver disease has been increasing in recent years. Alcoholic hepatitis, fatty liver disease, and alcoholic cirrhosis can occur in heavy or long-term drinkers. The patient has elevated alanine aminotransferase and aspartate aminotransferase, and the clinical presentation is similar to that of hepatitis.
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Don't know how much your aminotransferases are elevated? If it's just a little bit higher, it's not a big deal.
There are a variety of causes of elevated aminotransferases, such as staying up late, drinking alcohol, drugs, hepatobiliary diseases, myocarditis and myocardial infarction, strenuous exercise, overwork, or eating too greasy foods recently.
It is recommended to eat lightly, work and rest regularly, exercise moderately, and recheck liver function after two weeks.
If the retest is normal, it is transient and the aminotransferases are high, and there is no major problem.
If the retest is abnormal, a two-and-a-half test for hepatitis B should be done.
It is important to identify the cause of the elevated aminotransferases in order to correct the symptoms**.
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Some netizens found high aminotransferases during physical examinations, such as the recent college entrance examination physical examination.
If the antiviral** is effective, it can reduce the aminotransferases, after all, it reduces the damage to the liver, but it may be difficult to meet the standard in the short term. If the physical examination is to be carried out immediately or within a month, the combined application of antiviral** and hepatoprotective lowering enzyme** can ensure that the transaminases fall to normal levels as soon as possible under the premise that the aminotransferases are relatively high.
Although liver function tests are an important indicator for diagnosing various types of hepatitis, liver function tests are not the only indicator for diagnosing hepatitis, nor are they specific indicators. Because there are many reasons for abnormal liver function, including long-term heavy drinking, alcohol will make alanine aminotransferase high or taking antibiotics, if you take antibiotics in the early stage of blood drawing, it will also promote high alanine aminotransferase, after stopping the drug, it will be better after a period of time. It can also cause an increase in alanine aminotransferase during long journeys, continuous fatigue, or poor sleep and rest.
It should be reminded that before doing liver function tests, you must do them on an empty stomach, do not drink water, do not go to bed late the night before, ensure adequate sleep, in order to ensure the accuracy of the data, it is best to go to a regular hospital for liver function tests, if you are a patient with liver disease, you need to check your liver function regularly, you should also be active, not blind. At present, the best method for patients with liver disease is hepatocyte dialysis, which can quickly eliminate inflammation, relieve pain, promote hepatocyte metabolism, promote tissue repair, and promote tissue healing, with an effective rate of up to 98%, and significant improvement in five to ten days.
Customers who want to consult directly, no charge, 24-hour service.
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Hello, have you checked the hepatitis indicators, if not, it is better to check.
If there is no hepatitis, fatty liver should be considered if the blood lipid is high, and you can control your diet and strengthen exercise.
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If you need a qualified medical examination report, you can find someone to go for a physical examination on your behalf.
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I ate too much, I ate too much before the physical examination, my classmates seem to have tried it, and then I didn't eat indiscriminately at night before the physical examination, and it was fine to go for another physical examination the next day.
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Hello landlord:
Liver function tests are very common in clinical physical examinations and are also important indicators to assess health status, including aminotransferases, bilirubin, globulin, albumin and other indicators, which are often used to evaluate liver function and serve as one of the main diagnostic evidence of liver disease. If you have a history of hepatitis B, you must be vigilant and it is recommended to do an HBV DNA test, when alanine aminotransferase and HBV DNA are abnormal at the same time, hepatitis B is highly suspected. Once hepatitis B is found, it must be actively carried out**, in terms of drug selection, oral nucleos(t)ide drugs are stronger than interferon in terms of virus inhibition, and have the characteristics of high safety, small and low cost, so they are widely used in clinical practice and are favored by patients.
The localization of nucleos(t)ide drugs has greatly reduced the cost of domestic antivirals. Among the nucleos(t)ide drugs, according to the recommendations of the Guidelines for the Prevention and Treatment of Chronic Hepatitis B, it is recommended to choose the most powerful antiviral and low-drug resistant drugs, among which, the domestic drugs Runzhong (Entecavir Dispersible Tablets) and Mingzheng (Adefovir dispersible capsules) meet the above two requirements, and have high advantages in virus inhibition ability and drug resistance.
Hope it helps, thank you!
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Elevated aminotransferases are a very common condition and do not necessarily have a problem with the liver. Because transaminases are very sensitive, many factors will cause the normal value of transaminases to fluctuate up and down, healthy people check at different times of the day, transaminase measurement results may be different, early transaminase high generally use Schisandra chinensis liver tablets to reduce transaminases. The main reasons:
1. Healthy people will find that aminotransferases are elevated if they check for transaminases after strenuous exercise. 2. If you are overworked, it will lead to an increase in transaminases. 3. If you have eaten greasy food or alcohol before the examination, it will lead to an increase in aminotransferases.
4. Nutritional insufficiency: Unreasonable dietary structure, such as low-protein diet, especially when there is a lack of cystine and vitamin E in food, can also increase ALT. 5. The *** produced by daily drugs will also lead to an increase in aminotransferases, such as erythromycin, sleeping pills, antipyretic analgesics, contraceptive ointments, and traditional Chinese medicines such as banxia, betel nut, and indigo.
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There are several main reasons for high alanine aminotransferase: one is occasional and non-pathological factors such as drinking, staying up late, drugs, diet, exercise, pregnancy, etc., and after a period of reasonable adjustment, the value of alanine aminotransferase will return to the normal value (i.e., 0-40 u l); The other is caused by organ lesions, because alanine aminotransferase exists in multiple organ tissues, so organ lesions can also affect its value, such as myocarditis, Japanese encephalitis, cholecystitis, tuberculosis and other diseases. Alanine aminotransferase in adults mainly comes from the liver, viral hepatitis, liver cirrhosis, liver failure, fatty liver and other liver diseases will lead to abnormal values, it is best to carry out a systematic examination, once it is found that it is viral hepatitis, you need to seek medical attention in time to avoid delay.
Taking chronic hepatitis B as an example, if the patient's body alanine aminotransferase is slightly higher than the normal value, the liver function is basically normal, and the human body has no obvious discomfort symptoms, it can be temporarily discontinued**; If a patient with chronic viral hepatitis is elevated to more than 2 times the upper limit of normal, it means that the patient's immune function is active, and this is the best time to perform antiviral**, and the antiviral** effect will be better. There are two main ways of antiviral hepatitis B used in clinical practice: one is subcutaneous injection of interferon, and the other is nucleos(t)-based oral drugs.
The former is large, expensive, and has a narrow range of applications. However, the resistance rate of adefovir disodil in nucleos(t)ic oral drugs is low, but the antiviral efficiency is also low, and it can be used in combination with other antiviral drugs, which is suitable for patients with low hepatitis B viral load. Entecavir, on the other hand, is equivalent to the "heavy" of the antiviral war, with a strong antiviral effect and a relatively low drug resistance rate, which is suitable for hepatitis B patients with more active hepatitis B virus.
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Healthy people can also have elevated aminotransferases if they are overworked.
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Poor rest and drinking alcohol before the check-up can cause high aminotransferases.
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