What is the cause of glutamyl transpeptidase elevation to 1118

Hurry up and treat it, it will be troublesome if it grows into severe hepatitis.

1118？30 times higher than normal?? Isn't it, dude??

Glutamyl transpeptidase is one of the liver function tests, if it is to check that glutamyl transpeptidase is high, it means that there is liver damage, and liver function is abnormal, it is recommended to check other liver function indicators, and then according to the specific examination results and then scientific symptomatic**, Shijiazhuang PLA 256 Liver Disease Hospital is the first specialized hospital for liver disease, providing the best diagnosis and treatment services for patients with liver disease!

Reason 1 for high glutamyl transpeptidase: when intrahepatic or extrahepatic bile ducts are obstructed, the excretion of glutamyl transpeptidase is blocked, and it refluxes into the blood with bile, resulting in an increase in serum glutamyl transpeptidase.

Reason 2 for high glutamyl transpeptidase: Almost all patients with alcoholic hepatitis and alcoholic cirrhosis have increased glutamyl transpeptidase, which has become an important feature of alcoholic liver disease.

Reason 3 for high glutamyl transpeptidase: In acute viral hepatitis, the hepatocyte fairy enzyme synthesis adjacent to the necrotic area is excessive, resulting in an increase in serum glutamyl transpeptidase.

Reason 4 for high glutamyl transpeptidase: changes in serum glutamyl transpeptidase in cirrhosis depend on the activity of intrahepatic lesions and their **. It is usually normal during the inactive phase and tends to rise if it is accompanied by inflammation and progressive fibrosis.

Glutamyl transpeptidase is often elevated in the early stages of primary or secondary biliary cirrhosis. Some people believe that glutamyl transpeptidase is elevated in the early stage of liver cirrhosis, and the number of severe cases, especially in advanced cases, is very low, which may be due to the loss of hepatocyte glutamyl transpeptidase synthesis ability, so that if glutamyl transpeptidase is high in patients with cirrhosis, it is believed that the disease is still in the early stage.

Reason 5 for high glutamyl transpeptidase: In patients with primary or metastatic liver cancer, most of the enzyme is moderately or highly increased, which can be several times or even dozens of times greater than normal, while most of the tumors in other systems are normal. However, the results of R-GT for liver cancer overlap with other hepatobiliary diseases, especially with jaundice, so the single measurement of glutamyl transpeptidase has no diagnostic value for liver cancer, and alpha-fetoprotein is negative, while alkaline phosphatase and glutamyl transpeptidase are increased, especially in patients without jaundice, normal aminotransferases or only mildly elevated, should be highly vigilant for the possibility of liver cancer.

The sixth reason for the high glutamyl transpeptidase is that the glutamyl transpeptidase in fatty liver patients is often elevated, but in the case of nutritional fatty liver disease, the serum glutamyl transpeptidase activity is mostly not more than 2 times the normal value.

The seventh reason for the high glutamyl transpeptidase: in chronic active hepatitis, glutamyl transpeptidase is often 1-2 times higher than normal, and if it is elevated for a long time, there may be a tendency to liver necrosis.

If glutamyl transpeptidase is high alone, it is difficult to determine the cause of the disease, and further diagnosis and treatment is required.

Good luck.

In general, glutamyl transpeptidase is high [1] for the following reasons:

1. When suffering from acute viral hepatitis, the hepatocyte immortalase synthesis adjacent to the necrotic area is hyperactive, which causes the increase of serum glutamyl transpeptidase. This factor is also the most common and the most important to ignore.

2. In chronic active hepatitis, glutamyl transpeptidase is often 1-2 times higher than normal, and if it is elevated for a long time, there may be a tendency to liver necrosis.

3. When the bile duct is obstructed in the liver or extrahepatic, due to the obstruction of glutamyl transpeptidase excretion, the glutamyl transpeptidase will also be high with the reflux of bile into the blood.

4. Glutamyl transpeptidase in patients with alcoholic hepatitis and alcoholic cirrhosis has almost increased, which has become an important feature of alcoholic liver disease.

5. In patients with primary or metastatic liver cancer, glutamyl transpeptidase is mostly moderately or highly increased, which can be several times or even dozens of times greater than normal.

6. In the early stage of primary or secondary biliary cirrhosis, glutamyl transpeptidase will also be elevated.

7. Patients with fatty liver may also have elevated glutamyl transpeptidase, but in general nutritional fatty liver, the serum glutamyl transpeptidase activity is mostly not more than twice the normal value[2].

Analysis: Hello, from what you said, in the laboratory function is only R glutamyl transpeptidase is slightly higher, and other aspects of the test is normal, then don't worry too much, this does not mean that there must be a problem with the liver, opinions and suggestions: If you have no uncomfortable symptoms, you can observe for a period of time, during this period have a reasonable life and eating habits, keep a good mood, avoid overwork, this will be good.

In addition to hepatitis, there are other causes of elevated alanine aminotransferase.

Some reasons are as follows: 1. For some people who don't seem to have any serious diseases, there may also be alcoholic liver caused by long-term alcoholism, or fatty liver caused by unreasonable dietary structure, resulting in an increase in alanine aminotransferase. 2. If there are biliary obstructive diseases such as gallstones, the level of alanine aminotransferase in the blood may increase due to gall stabilis.

3. Many tissues in the human body contain aminotransferases, such as myocarditis and myocardial infarction, which may increase alanine aminotransferase. 4. Exertion may also increase aminotransferases. The above is an introduction to "what is the matter with elevated alanine aminotransferase", elevated alanine aminotransferase does not mean that you have hepatitis, but for people with a history of hepatitis, if there is an elevated aminotransferase, you must take into account the possibility of the condition, and go to a regular hospital for relevant examinations and positive ** in time.

What to do if glutamyl transpeptidase is high 40-80: mild; 80-150 : moderate; 160-200：

Height; 200 on: severe. If alanine aminotransferase and glutamyl transpeptidase are not very high, but only mildly to moderately elevated (no more than 5 times the upper limit of the reference value), plus high triglycerides, the possibility of fatty liver should be ruled out first, as long as an abdominal ultrasound is done at a glance.

Low zinc and cystatin C are not a big problem, and they are related to diet or excessive dieting, so don't worry too much. If these two enzymes are much higher, in addition to B ultrasound, you should also check the hepatitis B two and a half pairs and hepatitis C antibodies to rule out the possibility of viral hepatitis. As long as it is not viral hepatitis, the problem is not big, adjust the diet structure, try to quit smoking and drinking, or under the guidance of a doctor, through the assistance of drugs for a period of time, it will be fine.

Fatty liver, alcoholic liver, or staying up late for a long time will increase, autoimmune liver disease will also increase mildly, a single index can not explain the problem, you need to be based on your own situation and symptoms of comprehensive analysis, although if you suspect this 1 aspect of the problem, you should do the corresponding examination in time, such as fatty liver, alcoholic liver should be assisted by Western medicine B ultrasound diagnosis, autoimmune liver should go to the laboratory to do immunofluorescence matrix film or western blot ENA (targeted antigen) method to clarify, I hope it will help you, I wish you good health.

Causes of high glutamyl transpeptidase:

1. High glutamyl transpeptidase can be caused by primary liver cancer, adenocarcinoma, etc., especially in malignant tumors, with an incidence of up to 90%;

2. High glutamyl transpeptidase is common in liver diseases, such as: viral hepatitis, acute hepatitis, chronic hepatitis active stage, etc., and can also be seen in biliary diseases;

3. High glutamyl transpeptidase can also be caused by long-term alcohol addiction or long-term medication, and contraceptives can also cause high R-glutamyl transpeptidase.

Fourth, the high glutamyl transpeptidase may also be due to the progressive muscular dystrophy caused by people's high work pressure and serious environmental pollution, which eventually leads to the high glutamyl transpeptidase.

It is recommended to go to the hospital to further find out the cause and clarify **,

Causes of high R-glutamine transpeptidase.

1. Physiological situation R-glutamyl transpeptidase is high: it may be due to long-term alcoholism, or drug poisoning, long-term medication, high work pressure, and serious environmental pollution caused by progressive muscular dystrophy will also cause high aminoyl transpeptidase.

2. Pathological condition R-glutamyl transpeptidase is high: it is more common in patients with acute viral hepatitis, chronic active hepatitis, alcoholic hepatitis, alcoholic cirrhosis, fatty liver, primary or metastatic hepatitis, and most of the glutamyl transpeptidase in the body is moderately or highly increased.

3. Intrahepatic or extrahepatic bile duct obstruction: due to the obstruction of R-glutamyl transpeptidase excretion, with the reflux of bile into the blood, glutamyl transpeptidase will also be high. This is also a more common factor that needs attention.

The reference value of alanine aminotransferase is 0-40u L, alanine aminotransferase is also called, alanine aminotransferase (ALT), what is the cause of high alanine aminotransferase, there are many reasons for high alanine aminotransferase, such as: disease, drinking a lot of alcohol, taking antibiotics, irregular diet, poor rest, pregnant women, irregular menstruation, strenuous exercise, etc.! Alanine aminotransferase:

Alanine aminotransferase is present in the liver cytoplasm, an enzyme involved in the metabolism of human proteins (equivalent to a catalyst in industrial production), which plays a role in accelerating the conversion of protein amino acids in the body, and it is widely present in various tissues of the human body. Organ. Muscles.

In bones, the mitochondria of liver cells are the most, and the reference value of normal ALT in serum is: 9---51U L for males and 8---41UL for females (the test methods are different in each hospital, and the reference values are not exactly the same).

When various tissues and organs in the human body are active or diseased, the ALT in them will be released into the blood, so that the serum ALT content will increase. The higher the alanine aminotransferase, the more damaged the liver? For example, when the liver is inflamed, transaminases will be released from liver cells into the blood, the liver is damaged, serum aminotransferases are high, when one thousandth of liver cells have inflammation, serum aminotransferase content will be more than doubled, therefore, the number of serum aminotransferases is an important indicator of the degree of liver lesions.

If the alanine aminotransferase is high in hepatitis B patients, it means that the liver is inflamed, and it must be checked and **! Hepatologists once again remind everyone: **liver disease must go to a large professional hospital, and receive a professional ** in a timely manner, so as not to delay the condition, liver disease ** is different from other diseases**, do not go to the doctor indiscriminately, ** improper may lead to deterioration of the condition.

SDJF LDJ

So, what exactly? Copy.

In this regard, Professor Li Jiang, an expert in liver disease at the Liver Disease Hospital, pointed out that transpeptidase is an active DAO enzyme in the liver, and the normality of transpeptidase plays a very important role in determining whether there is hepatobiliary disease. The normal value of transpeptidase in men is not more than 40 u L, and the normal value of transpeptidase in women is not more than 30 u L.

1. High transpeptidase caused by pathological factors: 1. When obstructive jaundice occurs, the enzymes are abnormal, and they will reflux into the blood, and the transpeptidase will be high. 2. Hepatobiliary diseases can be transpeptidase high, common diseases include viral hepatitis, liver cirrhosis, cholangitis, primary hepatitis, extrabiliary ductitis, etc.

2. Physiological transpeptidase high: Frequent heavy drinking will also cause transpeptidase to be temporarily high, but this situation can generally return to normal after stopping drinking. Recommended Reading》 What are the precautions for checking liver function?

Through the above introduction of Professor Li Jiang, it can be seen that there are many reasons for high transpeptidase, so when you check for high transpeptidase, you should further go to a regular hospital for a comprehensive examination, diagnosis, and symptomatic.

Check the blood biochemistry when copying

After 12 p.m., fasting and blood should be drawn on an empty stomach the next day, otherwise the results of the test will not be accurate.

Glutamyl transpeptidase normal value 5 50Values above this indicate possible impairment of liver function. If glutamyl transpeptidase is elevated but aminotransferase is normal, then it is considered to be a case of liver disease, because it can be moderately elevated in viral hepatitis, cirrhosis, and acute hepatitis, and when transaminase returns to normal during the convalescent period, Y-glutamyl transpeptidase becomes the only elevated enzyme, indicating that hepatitis has not been cured, chronic hepatitis and cirrhosis are normal in the inactive phase, and the active phase or deterioration of the condition is continuously elevated.

In addition, alcoholic and drug-induced hepatitis is moderately or markedly elevated, but aminotransferases are normal. You can take a look at the test sheet, if the glutamyl transpeptidase is high but the aminotransferase is normal, then it is possible to have alcoholic liver, and it is recommended to go to the hospital for further examinations such as ultrasound.

There are many reasons for high transaminases, and specific ** needs to be further diagnosed, such as fatty liver, alcoholic liver, viral hepatitis or drug-induced liver injury, etc.

In most cases, the higher the transaminase, the more severe the liver damage, but the transaminase is normal, which cannot be completely equated with normal liver function.

Therefore, don't simply understand that as long as the transaminase is reduced, it is to restore liver function, simply reduce the transaminase, after stopping the drug, the real way to reduce transaminase is to restore liver function, after the liver function is restored, if it is viral, the virus index will slowly decline, **It is recommended to use traditional Chinese medicine, you can use Chinese patent medicine such as Liuwei Wuling tablets**, at the same time, you need to pay more attention to rest, correct your bad life and eating habits, such as quitting alcohol, appropriate exercise, Eat a balanced diet with foods high in protein, fruits and vegetables.