How to treat the hypoplasia of the corpus callosum on MRI examination in children?

Thinning of the corpus callosum is generally diagnosed by MRI imaging, which mainly suspects that the child has abnormal brain development and brain function, because the child is in the period of growth and development, if the child is in the same month and the same age in terms of growth and development, intellectual development and physical development, if there is no abnormality, it can be rechecked regularly. If the child has already developed the above developmental abnormalities, considering brain insufficiency, growth retardation needs to be diagnosed early, and early ** can take nutritional brain cell drugs. Therefore, the thinner corpus callosum is not seen in normal people.

Usually the baby should be strengthened exercise, should be given more nutrients to the baby's body, let the baby drink some milk, you can also try to let the baby walk.

In this case, you must give the child a comprehensive examination, and then listen to the doctor's words, perform ** or surgery, and be sure to encourage the baby.

1. Genetic factors: Dysplasia of the corpus callosum has a certain hereditary nature. Special syndromes such as genetic abnormalities in embryos and Aicardi's syndrome can lead to the occurrence of the disease in a hereditary way.

2. Toxic metabolic factors: During pregnancy, such as excessive alcohol consumption and alcohol poisoning by the mother, diabetes or some metabolic diseases in the embryo, it may lead to poor development of the corpus callosum.

3. Chromosomal abnormalities: chromosomal abnormalities are also one of the causes of callosome dysplasia, and the common chromosomal abnormalities are mainly trichromosome 18 and trichromosome 8.

4. Intrauterine infection in the embryonic stage: In the early embryonic stage, intrauterine infection and intrauterine ischemia will lead to abnormal development of the anterior part of the brain, resulting in the loss of the corpus callosum.

Dysplasia of the corpus callosum is usually a congenital cause and is hereditary. People with the disease generally have no special symptoms, but severe cases will have symptoms such as epilepsy and intellectual disability. Therefore, I hope to attract the attention of pregnant mothers, do regular prenatal check-ups during pregnancy, and pay attention to the diet of colleagues, and prevent and treat the disease through various aspects.

The child's corpus callosum is underdeveloped, which means that the connection between the left and right sides of the brain is poor, and the functions governed by the left and right sides of the brain are different. For example, the left brain controls the movement of the right limb, and the right brain controls the movement of the left limb. When the corpus callosum is underdeveloped, the control of the left and right brains in their respective areas will be poor, which will have a great impact on the child's later motor and language development, and mental retardation will occur, accompanied by seizures.

The main manifestations of hypoplasia of the corpus callosum in children are movement disorders and language disorders. The best time before the age of 3, and the blood-brain barrier is not fully mature, and the drug absorption is ideal.

Generally speaking, children's language talents such as speaking, language communication, etc., and motor talents such as crawling and walking, etc., if they obviously lag behind other children of the same age, it may be that the corpus callosum is leaking and thin; Poor development of the corpus callosum in children will cause relative intellectual disability and mental retardation. If the child has a thin callosum, parents must pay attention to timely**.

In the sagittal plane, coronal plane and axial plane, the corpus callosum can be absent or partially absent, such as: narrowing or disappearance of the hyaline septum, disappearance of the cingulate gyrus and cingulate sulcus, radial arrangement of the sulcus gyrus on the medial aspect of the brain on the median sagittal plane, enlargement of the ventricles or abnormal morphology. In addition to the complete absence of the corpus callosum, children with partial absence of the corpus callosum can also visually observe the absent parts, such as the compression, the body or the mouth.

The corpus callosum is the most important collection of myelinated fibers between the two hemispheres of the brain, connecting the two cerebral hemispheres and forming the roof of the lateral ventricles. It is one of the forebrain symphysis that occurs from the original plate.

The corpus callosum is formed at the 12th and 20th week of the embryo. At the 7th and 10th week of the embryo, there is a general thickening of the dorsal side of the endplate, above which a symphysis forms a symphysis, which induces the growth of axons in the cerebral hemisphere from one side to the other, forming the corpus callosum.

The earliest corpus callosum fibers can be seen on the embryo at 74 days of age, and the corpus callosum matures morphologically by 115 days.

If the symphysis block does not induce axons to cross the midline from one side of the cerebral hemisphere to the contralateral cerebral hemisphere, the corpus callosum cannot form. The corpus callosum is divided into four parts: mouth, knee, body and compression, and its development sequence is from front to back, which is exactly the opposite of its maturation order. Intrauterine infection, ischemia and other reasons in the early embryonic stage can cause the anterior brain to develop abnormally, and the corpus callosum is missing, and the late lesion can cause the pressure of the corpus callosum to be dysplasia.

The body and knee are often first affected, but both the knee and compression may be affected, but less often the knee alone is seen only in anecdotal anterior brain deformations. However, Barkovich (1988) suggested that corpus callosum dysplasia is due to damage to the prodromal phase of corpus callosum formation, rather than occurring during corpus callosum formation. There is also a genetic basis for achioplasia of the corpus callosum.

The underdeveloped corpus callosum is the dysplasia of the most important myelinated nerve aggregate between the two cerebral hemispheres, which can be divided into two types: complete dysplasia and incomplete dysplasia. The main cause is that there are no obvious symptoms in mild cases of corpus callosum dysplasia, but in severe cases, there will be intellectual disability, visual impairment and other diseases, and now there is no even if it can**.