Low thyroglobulin, what s the problem?

Analysis: There are many reasons for low thyroglobulin, the first of which may be caused by thyroid disease, such as thyroiditis, thyroid nodules, thyroid tumors, etc. Thyroid disease may lead to damage to thyroid epithelial follicles, resulting in low thyroglobulin, which usually requires a visit to the hospital for corresponding examinations and the guidance of a doctor** The primary disease can be improved.

Low thyroglobulin may also be caused by a lack of iodine, and if you do not pay attention to iodine supplementation, iodine deficiency will cause low thyroglobulin. Such patients need to pay attention to their daily diet and consume more iodine-containing foods, such as fish, crab meat, kelp, etc. In addition, low thyroglobulin may also be caused by thyroid surgery, which can damage the body's thyroid gland and cause abnormal function.

Thyroglobulin is a large glycoprotein secreted by thyroid follicular epithelial cells, most of which is synthesized by thyroid cells, and is low mainly in the following conditions:

1. Autoimmune diseases such as Hashimoto's thyroiditis or diffuse hyperthyroidism, due to the reduced function of thyroid follicular epithelial cells, too little thyroid hormone content in the body or lack of thyroid hormones secreted by itself, resulting in a large number of globulins and globulin antibodies binding to cause low thyroglobulin;

2. Thyroglobulin will decrease when congenital thyroid tissue is absent or thyroid hypoplasia, endemic cretinism, acquired thyroid gland is resected or completely resected;

3. The thyroglobulin is low after the use of drugs, such as iodine-131 radioactive**;

4. Iodine deficiency in the diet can lead to goiter and low thyroglobulin.

Causes of low thyroglobulinI believe that many people do not know much about thyroglobulin, in fact, this is a substance of thyroid follicular epithelial cells, and it also belongs to a macromolecular glycoprotein, which is also a component that can form glia in the follicular follicle of the thyroid gland, so it is very important. Nowadays, people have a lot of pressure in life, coupled with an unhealthy lifestyle, it is easy to produce the problem of low thyroglobulin, which will cause negative damage to the body, so only by knowing what the cause of low thyroglobulin is, can we avoid such symptoms, so what are the causes of low thyroglobulin?

Causes of low thyroglobulinThere are three main reasons for hypothyroglobulin, the first is that it is related to the healthy immunity of the human body, that is to say, whether it is congenital or acquired, the problem of low immunity will cause low globulin, which is caused by the problem of immune function deficiency. The second point is that the immunosuppressants taken have a suppressive effect on the body's immune system, and then cause the problem of low globulin. The third point is that because of severe hepatitis, decompensated cirrhosis and other symptoms, these types of diseases will damage liver function, and if the liver synthesis is reduced, it will cause globulin to be low.

The above is the reason for low thyroglobulin, so it can be found that if you want to avoid such symptoms, you first need to have a healthy lifestyle, regular exercise, fitness to improve your own immunity, and avoid too much fish and meat in your diet, and often eat rough grains, vegetables, melons and fruits.

Both are elevated, and the possibility of Hashimoto's thyroiditis (chronic lymphocytic thyroiditis) should be considered. The disease has a long course, from a few months to several years, and after mild or early cases**, the thyroid gland can be significantly reduced or return to normal size, symptoms can be relieved, signs disappear, and thyroid function returns to normal, so the prognosis is good. So, what causes high thyroglobulin?

There are several factors: 1) Autoimmunity. The disease has been shown to be closely related to autoimmunity.

2) Genetic factors. Studies have shown that the disease has HLA antigen polymorphisms. 3) The effects of iodine.

Excess iodine can cause thyroglobulin to be high. 4) Women with a previous history of toxic diffuse goiter. Asymptomatic thyroiditis is particularly common in the postpartum period.

Recommended reading: Tests for hyperthyroidism Thyroglobulin antibodies are a common autoantibody found in the serum of patients with autoimmune thyroid disease. It is of great significance for the development trend and ** of thyroiditis, especially Hashimoto's thyroiditis.

Serum ATGA is a specific indicator for diagnosing thyroid autoimmune disease, and is strongly positive in 80% of patients with chronic thyroiditis and 60% of patients with hyperthyroidism. Patients with hyperthyroidism will have transient hypothyroidism in the process of **, and the occurrence of this condition is closely related to ATGA. ATGA can be used as an indicator in the differential diagnosis of a thyroid mass, and a positive result is generally considered to be chronic lymphocytic thyroiditis rather than a thyroid mass.

Tips: A single examination index cannot completely analyze the condition, and there are other examination indicators that need to be comprehensively analyzed. You can send the examination report to the director of Harbin Public Security Fire Hospital, and decades of thyroid clinical experience believe that it can help you clearly analyze the condition.

Suggestion: Your condition may be endocrine-related.

High antithyroglobulin antibodies are autoimmune inflammation and thyroiditis may be considered. It is recommended to go to a professional hospital for a comprehensive examination, and actively look for**and**.

The drug is one of the three effective methods, but it is easy to stop the drug, the dosage needs to be adjusted gradually, and it needs to be taken for a considerable period of time after the maintenance dose.

Yang Hui, Henan Provincial Cancer Hospital.

Low thyroid-stimulating hormone and high thyroglobulin antibodies are indicators of Hashimoto's hyperthyroidism. Hashimoto's disease, known as chronic lymphocytic thyroiditis and toxic diffuse goiter, are both autoimmune thyroid diseases. A combination of the two can sometimes be found, and such pathologies are commonly referred to as Hashimoto's toxosis and Hashimoto's hyperthyroidism.

Patients will have various manifestations of systemic hypermetabolism to varying degrees, such as palpitation, sweating, heat intolerance, polyphagia, weight loss, and goiter.

Elevated thyroglobulin antibodies and elevated thyroid peroxidase antibodies are manifestations of autoimmune thyroiditis. Decreased thyroid-stimulating hormone is usually a manifestation of hyperthyroidism or thyrotoxicosis. It is recommended to check thyroid-stimulating hormone receptor antibodies, and if possible, you can check the thyroid iodine uptake rate and thyroid ect.

Differentiation between hyperthyroidism and destructive thyrotoxicosis is currently needed. Hyperthyroidism generally refers to toxicity, diffuse goiter is also called Graves' disease, this disease is caused by the thyroid gland synthesis and secretion of excessive thyroxine, generally thyroid-stimulating hormone receptor antibodies are elevated, and the thyroid iodine uptake rate is also increased, if the thyroid technetium uptake rate will be increased. In addition, destructive thyrotoxicosis is not ruled out, this condition is thyroid inflammation destroys the thyroid gland, resulting in the transient release of thyroxine stored in the thyroid gland, caused by excessive transient release, this situation thyroid-stimulating hormone receptor antibodies are generally normal, but the thyroid iodine uptake rate is definitely reduced, and the technetium uptake rate of the ECT thyroid gland is reduced.

Current tests do not distinguish between them. In addition, thyroid ultrasound is required, but color ultrasound can only look at the general judgment of blood flow, and cannot determine whether it is hyperthyroidism or destructive thyrotoxicosis. Thyroid-stimulating hormone receptor antibodies should be checked first, and it is best to go to a hospital where conditions are available to check thyroid iodine uptake rate or ECT.

Analysis: Hello, thyroglobulin is low, thyroid hormone secretion will be relatively high, which can lead to the occurrence of hyperthyroidism, suggestions: Hello, it is recommended that you eat less spicy food, seafood, taboo strong tea, coffee, tobacco and alcohol.

Try to keep your mood happy! Wishing you good health!

Analysis: Hello, thyroglobulin is low, and thyroid hormone secretion will be relatively high, which can lead to the occurrence of hyperthyroidism.

Suggestions: Hello, it is recommended that you eat less spicy food, seafood, and taboo strong tea, coffee, tobacco and alcohol. Try to keep your mood happy! Wishing you good health!

Thyroid gland (Latin: glandula thyr(e)oidea; English: thyroid) is a very important gland in vertebrates, belonging to the endocrine organs.

In mammals it is located in the neck below the thyroid cartilage, on both sides of the trachea. The human thyroid gland resembles a butterfly and resembles a shield, hence the name. The thyroid gland controls the rate at which energy is used, makes proteins, and regulates the body's sensitivity to other hormones.

The thyroid gland relies on the production of thyroxine to regulate these responses, including triiodothyronine (T3) and thyroxine, also known as tetraiodothyronine (T4). Both regulate metabolism, growth rate, and other body systems. T3 and T4 are synthesized from iodine and tyrosine.

The thyroid gland also produces calcitonin, which regulates the balance of calcium in the body.

。It is recommended that the patient go to the hospital in time to find out the situation, and if the problem is found, it will be carried out in time**.