Chromosomal structural variation, type of chromosomal structural variation

There are four main types of variation in chromosome structure.

1. Deletion, the deletion of a segment of a chromosome.

2. Add or add a certain segment of chromosomes.

3. Inversion, a segment of the chromosome is reversed by 180°

4. Translocation, transfer of a segment of a chromosome to another non-homologous chromosome.

Cause; Under the action of certain natural or man-made factors, chromosomes may break, and the broken ends have the ability to heal and reconnect. Structural variation occurs when chromosomes are broken in different segments and reconnected in different ways between the same chromosome or different chromosomes.

Under the influence of natural conditions or human factors, there are four main types of structural variation on chromosomes:

1.Deletion Deletion of a Segment of a Chromosome For example, meowing cat syndrome is a genetic disorder caused by a partial deletion of chromosome 5 in a person, named because the child cries softly, in a high-pitched voice, much like a cat meow. Patients with meow cat syndrome have distant eyes, low ear position, stunted growth and development, and severe intellectual disability; The formation of missing wings in fruit flies is also due to the deletion of a chromosome.

2.Duplication A chromosome adds a fragment The rod-eye phenomenon in Drosophila is caused by a partial duplication on the X chromosome.

3.Inversion A segment of a chromosome is reversed by 180 degrees, resulting in a rearrangement of the chromosomes, such as a female habitual miscarriage (inversion of the long arm of chromosome 9).

4.Translocation A segment of a chromosome that is transferred to another non-homologous chromosome or to a different region on the same chromosome, such as inertial leukemia (partial translocation of chromosomes 14 and 22, which is often the case with nightshade).

There are four types of chromosomal structural variation: deletion, duplication, inversion, and translocation. Chromosomal structural variation is the result of the combined action of internal and external factors, including the imbalance and aging of the metabolic process of organisms, and external factors including radiation, chemical agents, and drastic changes in temperature. There are four types of chromosomal structural variations: deletion, duplication, inversion, and easy to argue.

Chromosomal structural variation is the result of the combined action of internal and external factors, including the imbalance of the metabolic process of organisms and aging, and external factors including the imbalance of the reputation line, chemical agents, and drastic changes in temperature.

The causes of chromosome structural variation include physical factors, chemical factors, biological factors, maternal age effects, etc. The types of variation in chromosome structure are deletions, deletions of a certain segment of a chromosome; Adding, chromosomes add a certain segment; Inversion, a segment of the chromosome is reversed by 180°; Translocation, the transfer of one segment of a chromosome to another non-homologous chromosome. The causes of chromosome structural variation include physical factors, chemical factors, biological factors, maternal age effects, etc.

The types of variation in chromosome structure are deletions, deletions of a certain segment of a chromosome; Adding, chromosomes add a certain segment; Inversion, a segment of the chromosome is reversed by 180°; Translocation, the transfer of one segment of a chromosome to another non-homologous chromosome.