Side effects of taking medicine How to solve itching on the body

Erovade (leflunomide leftunomide, LEF) is a disease-modifying drug, is a new type of isoxazole immunosuppressive drugs with anti-proliferative activity, which is converted into the active metabolite A771726 in vivo after oral administration, and affects the pyrimidine synthesis of activated lymphocytes by inhibiting dihydroorotate dehydrogenase activity, and plays a role by reducing the production of pyrimidine. In vitro and in vivo tests have shown that the drug has an anti-inflammatory effect. The in vivo activity of leflunomide is mainly produced through its active metabolites; Foreign clinical trials have confirmed that the drug has obvious efficacy in rheumatoid arthritis, and was approved for marketing in the United States on September 11, 1998, becoming another new drug for rheumatoid arthritis.

The dosage is 50 mg once daily for the first 3 days, followed by 20 mg once daily.

In order to study the efficacy and safety of the American Xinkai company developed by Ironova on rheumatoid arthritis patients in China, from February 1998 to February 1999, 9 randomized, controlled and parallel clinical trials were organized nationwide, including double-blind and single-blind trials, the control drug was methotrexate, the course of treatment was 12 weeks, and some cases were used for 24 weeks. A total of 566 patients were randomly assigned to the experimental group and the control group, and 504 patients completed the trial, including 291 patients in the experimental group and 213 patients in the control group. In this trial, it was found that Erova significantly improved the clinical signs and symptoms of patients, and its efficacy was not significantly different from that of methotrexate.

The onset time of Erova is 3 to 6 weeks, and it reaches stability after 3 months of medication. Foreign studies have confirmed that Erova can effectively prevent the progression of the disease for one year, which is better than methotrexate; The combination of Erova and methotrexate for refractory rheumatoid arthritis has obvious effects.

Erova's *** is mild, and there may be diarrhea, itching, rash, hair loss, elevated aminotransferases, etc. Severe liver and kidney insufficiency, active gastrointestinal disease, immune deficiency, etc. should be used with caution. Pregnant women, women of childbearing age and lactating women who have not yet taken reliable contraceptive measures, and those who are allergic to this product are prohibited.

The efficacy and safety of this product for children have not been studied in detail, so it should not be taken by children.

It may be an allergic reaction.

The use of this drug should be stopped and the doctor should be seen in a timely manner. You can take some anti-allergy drugs first, such as: chlorpheniramine, loratadine and so on.

Drinking plenty of boiled water and milk in a bath can solve the problem.

Immediate oral aspirin.

Disease analysis: Hello, according to your description, this does not rule out the possibility that Burning Wangwan is an allergy, and it is generally believed that sensitivity is a highly intolerant state, which is susceptible to various factors and produces subjective symptoms such as stinging, burning, tightness, itching, etc.

Guidance: It is recommended that you go to the pharmacy to buy chlorpheniramine oral and calamine lotion for external use**.

Is it allergic or hi what's wrong.

You don't have to drink medicine, pick a piece of aloe vera and apply it to the itchy area.

Disease analysis: Hello, the drug is generally metabolized by the liver and kidney function through the sock chain, and it should be considered that it is harmful to the liver and kidney if you take the drug for a long time. If you take the drug for a long time, it is recommended that you should monitor liver and kidney function regularly.

Suggestions: Any drug should not be used for a long time, and it may also produce lead resistance. I wish you health and happiness.