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Non-invasive DNA, of course.
Non-invasive DNA prenatal testing is to collect the peripheral blood (10ml) of pregnant women, extract free DNA, use a new generation of high-throughput sequencing technology, combined with bioinformatics analysis, to obtain the risk rate of fetal chromosomal aneuploidy disease (trisomy 21, also known as Down syndrome, trisomy 18, trisomy 13). The best detection time of this method is in the first and second trimesters, and it has the characteristics of non-invasive sampling, no risk of miscarriage, high sensitivity and high accuracy. You can consult with your relatives!
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1. Non-invasive DNA test does not need fasting: Non-invasive DNA test requires drawing maternal blood. On the contrary, there is no need to fasting when doing non-invasive DNA tests, and pregnant mothers can just ensure a normal diet.
2. Pay attention to the examination time: non-invasive DNA prenatal testing can be carried out at 12 weeks of pregnancy, and 12 weeks and 26 weeks of pregnancy are the entire time period for non-invasive DNA prenatal testing. If expectant mothers want to do this examination, they must do it during this time period, so as not to affect the results of the examination and improve the accuracy of the examination.
3. Non-invasive DNA testing is not the same as Down's screening: Down's screening is only one of the non-invasive DNA tests, which means that there are many non-invasive DNA tests, including Down syndrome, Edwards syndrome, Patau's syndrome and other chromosomal diseases. Therefore, pregnant mothers should adhere to all the examination items when doing non-invasive DNA tests to ensure the health of the fetus in an all-round way.
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Summary. Dear, non-invasive DNA testing is relatively accurate, and its accuracy rate can reach more than 90%. Non-invasive DNA is a prenatal screening method, compared with Down's screening, its sensitivity and specificity are high, and the accuracy rate of screening for trisomy 21, trisomy 18 and trisomy 13 can reach 99%, 97% and 91% respectively, and the false positive rate is low, suitable for pregnant women over the age of 35 or pregnant women with Down's screening at critical risk.
In addition to its accuracy, it is also non-invasive, and compared to amniocentesis, non-invasive DNA tests are blood tests that do not increase the rate of fetal loss. However, non-invasive DNA is not a substitute for amniocentesis, although its accuracy rate is high, but it cannot confirm the diagnosis, once one or more non-invasive DNA is at high risk, further amniocentesis should be done to identify.
Are the results of non-invasive DNA tests accurate?
Excuse me, are you Changchun Qianmai?
Dear, non-invasive DNA testing is relatively accurate, and its accuracy rate can reach more than 90%. Non-invasive DNA is a prenatal screening method, compared with Down's screening, its sensitivity and specificity are high, and the accuracy rate of screening for trisomy 21, trisomy 18 and trisomy 13 can reach 99%, 97% and 91% respectively, and the false positive rate is low, suitable for pregnant women over the age of 35 or pregnant women with Down's screening at critical risk. In addition to its accuracy, it is also non-invasive, and compared to amniocentesis, non-invasive DNA tests are blood tests that do not increase the rate of fetal loss.
However, non-invasive DNA is not a substitute for amniocentesis, although its accuracy rate is high, but it cannot confirm the diagnosis, once one or more non-invasive DNA is at high risk, further amniocentesis should be done to identify.
Dear, no, I'm from Quanzhou City.
After the non-invasive procedure, the cerebral effusion was detected.
Pro, non-invasive DNA, mainly to check for chromosomal problems in the fetus. Formal noninvasive DNA testing does not detect hydrocephalus or most rare or hereditary diseases. Therefore, non-invasive DNA detection also has certain limitations.
It is recommended that a regular hospital should do a corresponding pregnancy examination during pregnancy to detect it early and ** early.
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Not the same. Depending on the age and risk of sugar screening, the items that need to be checked for each pregnant woman are also different.
NT check
NT stands for Nuchal Translucency, which refers to the "nuchal translucency", which is the maximum thickness between the horizontal sagittal surface of the fetal cervical spine** and the subcutaneous soft tissue. The NT test is also used to diagnose early Down syndrome screening and is designed to diagnose chromosomal disorders and detect fetal abnormalities due to multiple causes in early pregnancy. Checking the thickness of the fetal cervical spine by color ultrasound is a routine test to rule out fetal malformations!
If the test is more than 3 mm, it often indicates an adverse fetal outcome. It is necessary to focus on recording so that the doctor can be prompted to pay attention to it during the later screening of Down syndrome (16-18 weeks) and the exclusion of four-dimensional color ultrasound (24 weeks).
Non-invasive DNA is suitable for the population
1.Pregnant women who are of advanced age (age 35 years) and do not wish to opt for invasive prenatal diagnosis;
2.Pregnant women whose results are at high risk or have changed the value of individual indicators, and are unwilling to choose invasive prenatal diagnosis;
3.Pregnant women with increased fetal NT value or other anatomical abnormalities during pregnancy B ultrasound, and unwilling to choose invasive prenatal diagnosis;
4.Pregnant women who are not suitable for invasive prenatal diagnosis, such as virus carriers, placenta previa, placenta low-studded, oligohydramnios, negative rh blood group, history of miscarriage, threatened miscarriage or precious babies, etc.;
5.Pregnant women who have failed to culture amniocentesis cells, are unwilling to undergo again or can no longer undergo invasive prenatal diagnosis; Pregnant women who wish to exclude fetal trisomy 21, trisomy 18, and trisomy 13 and voluntarily choose to undergo non-invasive prenatal testing.
6.Pregnant women with positive seroscreen and pregnant women with psychological disorders with prenatal diagnosis;
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The accuracy rate of non-invasive DNA in pregnancy tests is usually higher than 90 percent, and the accuracy rate of Tang screening is only 70 percent.
Non-invasive DNA is a safe, non-risk test that can accurately screen the risk of fetal trisomy T21, T18, and T13 aneuploidy disease.
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Accuracy of Non-Invasive DNA:
Compared with the mainland, non-invasive DNA in the mainland generally only detects the basic three items (three autosomes: trisomy 21, trisomy 18, and trisomy 13), while the non-invasive DNA of Kigang can detect 5 sex chromosome abnormal syndromes, 6 triploidy syndromes, and 84 microdeletion or duplication syndromes, with a total of 95 items, which is more comprehensive.
Compared with traditional Tang screening, the accuracy of 10-week non-invasive DNA prenatal testing in Hata Port is higher than that of more than 3,000,000 cases. The test can be carried out at 10 weeks of pregnancy, and the report will be issued in 7-10 working days.
Testing can be consulted Zhuoyu Health, with specific items and information.
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Maternal plasma contains cell-free DNA from the fetus, which provides a realistic basis for the project. Fetal chromosomal abnormalities can cause small changes in maternal DNA content, which can be detected through deep sequencing and bioinformatics, providing a theoretical basis for the project. In addition to the detection of chromosomes 13, 18 and 21, the Hong Kong test also contains 94 microdeletions and microduplications.
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In fact, this problem should be looked at this way: according to the data released by the Health and Family Planning Commission, the true incidence of trisomy 21 (Down syndrome) in China is about 5 per 10,000, but the misdiagnosis rate of non-invasive prenatal examination is as high as 1 to 2 per 1,000 (the international authoritative medical journal "New England Medicine" in August 2014**), which is 2-4 times the true incidence.
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The accuracy and detection rate of non-invasive DNA are both above 99%, that is, for a small cardinal event such as a single user, its accuracy can be said to be absolute, but it is said that it is a detection item that needs to be expressed by probability.
Non-invasive DNA is directly sequenced by sequencing the free fetal DNA genetic material in the peripheral blood (venous blood) of pregnant women, so its detection rate and accuracy can be well guaranteed. It's the most straightforward way.
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Isn't it asking what is the accuracy rate of DNA testing? More than 95%.
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The accuracy rate of non-invasive DNA is about 96%, and the accuracy rate of amniocentesis is up, but amniocentesis is invasive. I hope my answer will help you! Non-invasive DNA is OK throughout the pregnancy cycle, and there is no time accuracy that is high, and Down's screening takes time.
Guidance: It is recommended that you eat less spicy food during pregnancy, quit smoking and alcohol, eat folic acid tablets in the first three months of pregnancy and the first three months of pregnancy, and it is best to have regular prenatal check-ups and follow the doctor. If you have a problem, you can see a doctor at any time.
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The testing company certified by the National Health and Family Planning Commission can achieve the above accuracy.
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Choose a guaranteed institution with an accuracy rate of up to 98%.
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For the detection of chromosomes, the accuracy rate is reached.
Non-invasive DNA testing is to collect the peripheral blood of pregnant women for informatics analysis to determine the risk of fetal trisomy 21, trisomy 18, and trisomy 13. Ordinary non-invasive DNA tests mainly screen for the above three chromosomal diseases, and the price is about a few thousand, and some provinces and cities have recently carried out free tests. At present, a number of hospitals have also carried out upgraded non-invasive DNA tests, in addition to screening the above 3 diseases, 4 sex chromosome diseases, and another 93 chromosomal diseases, a total of 100 chromosomes are screened, ** in two or three thousand yuan.
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