I wonder if my mom s condition is not MND

Motor neuron disease (MND) is a group of progressive degenerative diseases that are not identified and selected to commit a certain part of the motor nervous system. The extent of the lesion includes anterior horn cells of the spinal cord, motor nuclei of cranial nerves, cortical pyramidal cells, corticobulbar tract, and corticospinal tract. Clinical manifestations include lower motor neuron damage and corresponding muscle atrophy, weakness, bulbar palsy, and signs of upper motor neuron (pyramidal tract) damage.

The sensory system is generally inviolable. At present, there is no substantial means to slow down the progression of the disease, and the average survival is only about 3 to 5 years from the onset of symptoms. This group of diseases is mainly seen in the elderly, and occasionally in young people, with an average age of onset of 55 years.

90% of patients are sporadic, 10% are familial, and are usually inherited in an autosomal dominant manner.

The main tests and diagnosis are based on electromyography, CT, or MRI.

I would like to send you the test for MND and do a self-test.

Motor neuron disease (MND) is more common in middle age, with insidious onset and rapid progression, with no obvious sensory impairment at the initial stage.

The different types of MND have clinical manifestations of:

Progressive spinal muscular atrophy: symmetrical motor neuron paralysis of the limbs, but initial atrophy may be limited to one limb or part of it.

Primary lateral sclerosis: symmetrical upper motor neuron paralysis of the limbs, and rarely pseudobulbar palsy.

Amyotrophic lateral sclerosis: more common. It begins with atrophy and weakness of the small muscles of one hand, gradually spreads to the muscles of the opposite hand, forearm, upper arm, scapula and other muscles, and has symptoms of lower motor neuron paralysis such as fasciculation, but tendon hyperreflexia.

Both lower extremities present with typical symptoms of upper motor neuron damage, occasionally in one upper and lower extremity.

4) Ancillary examination: Electromyography shows typical denervation changes, with occasional high-amplitude and long-term wave patterns. Muscle biopsy shows typical pathology of denervation amyotrophy.

Motor neuron disease is generally difficult to completely, there will be some different degrees of symptoms, usually caused by motor neuron damage, according to the patient's situation to actively cooperate with the doctor's **, take relevant drugs to alleviate the development of the disease. Motor neuron disease is a heterogeneous disease, with a variety of genres and no influence on each other, so it must be a combination of methods, including **, symptomatic ** and various non-drugs**, patients will have respiratory failure in the late stage, and sometimes sudden dyspnea and emergency.

You don't necessarily die if you have motor neuron disease. Motor neuron disease is also a kind of ALS, which is not contagious, but it is related to family genetic factors, and it may be accompanied by muscle atrophy after the disease, although there will be no immediate death, and the life period may be delayed if it is well controlled, but it will also slowly lose life over time. When MND attacks, it is likely to be accompanied by varying degrees of symptoms such as muscle weakness and difficulty swallowing.

Generally speaking, patients with neuromotor neuron disease are promising, but there is no way to eat completely, and can only be improved by corresponding drugs.

Motor neuron disease (MND) is a very common and troublesome disease, which is caused by the lesion of the nerves, and the nerves are non-renewable, which is very harmful to the body and requires special attention.

Mixed form of upper and lower motor neuron disease. Usually the first symptom is hand muscle weakness and atrophy, which generally starts from one side and then spreads to the opposite side, and with the development of the disease, there are mixed symptoms of upper and lower motor neuron damage, which is called amyotrophic lateral sclerosis. In the late stage of the disease, the muscles of the whole body are emaciated and atrophied, so that they cannot raise their heads, have difficulty breathing, and are bedridden.

The disease usually occurs between the ages of 40 and 60, and about 5 to 10% have a family history, and the course of the disease varies in speed and progression.

The best way to treat motor neuron disease is as follows:

1. Drugs**: anti-excitant amino acid toxic drugs can be used to delay the development of early diseases, and muscle relaxants, antioxidants, etc. can reduce patients' joint contractures, joint stiffness, drooling and other symptoms;

2. Oxygen therapy: For patients with respiratory weakness, oxygen therapy can be carried out through a simple home ventilator to reduce the symptoms of dyspnea or respiratory failure;

3. Surgery**: If the patient has swallowing dysfunction, the gastric tube can be indwelled in the short term, and the gastrostomy can be performed in the long term;

4. Psychology**: Psychological assessment and psychological counseling can help patients understand and face diseases.

Determine if you have exercise, who rescues the disease can look at your symptoms, if you walk unsteadily, and often have headaches, you may have motor neurons.

Motor neuron disease.

Typical symptoms. Muscle weakness, muscle atrophy, and fasciculations are manifestations of lower motor nervous system involvement; Hypertonia, hyperreflexia, and positive pathological signs are the main manifestations of upper motor nervous system involvement.

Other symptoms. The presenting symptom can be a variety of manifestations depending on the patient. Most patients have asymmetrical local limb weakness, such as stiff walking, procrastination, easy falling, and inflexible finger movement. Bulbar symptoms such as dysphagia and dysarthria.

A small number of patients present with respiratory symptoms.

There is a high probability that the typical symptoms are present.

Diagnosis of MND is based on medical history, physical examination, electromyography, imaging tests, muscle biopsies, etc. Among them, electromyography has great diagnostic value. At present, there is still a lack of effective methods for motor neuron disease, which can only relieve symptoms and alleviate patients' suffering.

The pathogenesis of motor neuron disease is not yet fully understood, and it is considered to be related to many factors, including the following:

1. Infection and immune disorders. Prion and HIV infections may be associated with the pathogenesis of MND. Clause.

2. Poisoning of certain metals or lack of elements. Aluminum poisoning may cause amyotrophic lateral sclerosis. Clause.

3. Genetics. Most MND is sporadic, but 10% of patients have a family history. Clause.

4. Nutritional disorders. Vitamin B deficiency may be associated with the onset of motor neuron disease. Clause.

5. Neurotransmitter abnormalities. Glutamate and aspartic acid are neurocytotoxic and may play a role in the pathogenesis of amyotrophic lateral sclerosis.

1. There is no sensory impairment in motor neuron disease.

2. Motor neuron disease muscle biopsy is a typical pathological change of denervating amyotrophy.

3. Motor neuron disease develops after middle age and progressively worsens.

4. Motor neuron disease has ruled out cervical spondylosis, brainstem tumors, syringomyelia, cervical cord tumors, etc.

5. There was no abnormality in the examination of cerebrospinal fluid in motor neuron disease.

6. Motor neuron disease is characterized by symptoms and signs of upper and lower motor neuron damage.

7. Electromyography of motor neuron disease showed neurogenic damage. Nerve conduction velocity is usually normal.

The symptoms of motor neuron are also manifested in limb weakness, increased muscle tone, difficulty walking, tightness, and ineffective movements. However, this phenomenon belongs to the upper motor neuron type, which usually begins in adulthood and generally progresses very slowly.

There are many factors that can lead to MND, such as exposure to special biologics, ionizing radiation, and the effects of toxic substances, or abnormalities in autoimmune mechanisms, or genetic factors in the family. These patients may then have some oxidative damage and damage to excitotoxic substances, resulting in abnormal motor neuron function.

Then the patient may have motor neuron disease, such patients are prone to atrophy and weakness of the muscles of the limbs, and will also be combined with symptoms such as dysphagia, choking on drinking water, dysarthria, etc., and these patients need to carry out long-term limb exercises.

Motor neuron disease (MND) is a syndrome of impotence in traditional Chinese medicine, which is a syndrome of sluggish and weak limb muscles. Traditional Chinese medicine believes that the kidney is the innate foundation, the main essence is stored, and the bone is the marrow. In traditional Chinese medicine, it is most closely related to the kidneys, with insufficient congenital endowment, lack of sperm and blood, and inability to nourish muscles, muscles and bones, and gradually muscle weakness and atrophy.

At the same time, the spleen and stomach are the foundation of the day after tomorrow, metamorphosis generates qi and blood, nourishes the five internal organs, muscles, muscles and bones, and the spleen is the main muscle, the spleen and stomach are weak, the biochemistry of qi and blood is insufficient, and the muscles are not nourished, so the muscles are atrophied and weak.

Motor neuron disease is a chronic progressive neurodegenerative disease manifested by damage to upper and lower motor neurons, the onset of this disease is relatively insidious, the progress is relatively slow, and the prognosis is not good. At present, there are various hypotheses, and the more unified understanding is that on the basis of genetic background, oxidative damage and excitotoxicity work together to damage motor neurons, mainly affecting the structure and function of mitochondria and cytoskeleton of motor neurons. Elderly men, who have a history of trauma, excessive physical labor, such as miners, heavy physical labor, may be risk factors for the disease, in addition to infection and immunity factors, heavy metal poisoning, the absence of certain trace elements, genetic factors, some patients themselves will have nutritional disorders, as well as neurotransmitter abnormalities, are all morbidity**.

Motor Neuron Disease (MND) Approach to MND is mainly divided into 6 major aspects of heredity, familial MND DNA gene mutation encoding CU Zn superoxide dismutase SOD on chromosome 2, oxidative stress in non-replicating cells, such as neurons, the effects of oxidative stress may be cumulative, damage caused by free radicals is the main underlying cause of several neurodegenerative diseases associated with age-related neuronal decline, toxic factors, excitotoxic neurotransmitters, and immune factors, viral infection, susceptibility of motor neurons to neurodegeneration.

Diseases like this one have something to do with a vitamin deficiency in your body.

Motor neuron disease is still unclear, and it is considered to be related to genetic factors, environmental factors, etc., such as genetic susceptibility to people with a higher risk of disease than the general population; There are relatively many environmental triggers, including trauma, fall injury, etc.; The clinical manifestations of motor neuron disease are muscle weakness and muscle atrophy, and the differentiation is mainly different from diseases with the same manifestations; Myasthenia gravis is mainly characterized by morning and evening heaviness and proximal muscle weakness, such as upper arm, respiratory muscle and other muscle weakness, which can be distinguished; In addition, it is also necessary to distinguish from muscle atrophy and metabolic diseases, such as progressive muscular dystrophy, glycogen storage disease, and granular brain disease.

There are many causes of this disease, so there is no way to tell.