Which drugs can be taken for hypertensive nephropathy to effectively treat the condition

Both kidney cysts are the same regardless of gender, regardless of severity. It is usually occasionally discovered when you go for a test for some other reason. Many people with cysts in both kidneys don't know they have the disease.

However, severe disease of both kidneys is extremely rare. The vast majority of patients with kidney cysts are asymptomatic. It is possible to live a healthy life with illness, and only some patients can have some symptoms due to the cyst itself and the increased pressure in the cyst, infection, etc.:

For example, discomfort or pain in the lower back or abdomen: This is caused by the enlargement and expansion of the kidneys, which increases the tension of the renal capsule, stretches the renal pedicle, or compresses adjacent organs.

Combined with the described situation, it is recommended to give the following guidance: 1 The most important thing for any kidney disease is to avoid the use of kidney damage drugs, so you should read the instructions before using any medicine, or consult a doctor 2 For the blood creatinine situation, it is more appropriate to take ACE inhibitors (pril) ARB (sartan) antihypertensive drugs, first of all, they are all exact antihypertensive drugs, and secondly, they all have a protective effect on the kidneys (blood creatinine "400mmol L, high blood potassium should not be used) Angiotensin plays an important role in the progressive deterioration of renal failure, Therefore, ACE inhibitors (prilis angiotensin-converting enzyme inhibitors) and ARBs (sartan angiotensin receptor antagonists) all have a protective effect on the kidneys

Creatinine is non-toxic and is divided into two types: serum creatinine (blood creatinine) and urine creatinine. Creatinine is a product of muscle metabolism in the human body, and 1mg of creatinine can be produced for every 20g of muscle metabolism. Creatinine produced in the body is mainly excreted by glomerular filtration.

High creatinine is due to a problem with filtration. There are two kinds of blood creatinine: exogenous and endogenous, exogenous creatinine is the product of meat food metabolism in the body; Endogenous creatinine is a product of muscle tissue metabolism in the body. When the intake of meat is stable, and there is no major change in the body's muscle metabolism, the production of creatinine will be relatively constant, and there will be no high creatinine.

In other words, if kidney function is impaired, creatinine will be high. Creatinine levels reflect the status of kidney function in patients with renal failure. The higher their levels, the more severe the degree of impairment in kidney function.

Hypertension is an important cause of deterioration of kidney function in chronic nephritis, so we should strive to control blood pressure within the ideal range, which is less than 1380 mm Hg. Chronic nephritis often has volume-dependent hypertension due to sodium and water retention. Therefore, for this kind of efficient **, you can choose such as dihydrogram urathia.

If the front medicine is ineffective, it can be changed to Panli, but it is generally not suitable for too much or long-term use. It can also be used, other ** drugs of choice for chronic nephritis hypertension, of course, if chronic nephritis has renal insufficiency, ACE inhibitors or ARB drugs should be used to prevent hyperkalemia, in addition, the selection of chronic nephritis hypertension drugs can be used calcium ion antagonists, receptor blockers, receptor blockers, etc. Chengdu Xinhua Hospital :

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For patients with hypertension and kidney disease, the following classes of antihypertensive drugs can be taken in:

1. Diuretics can be taken, but long-term and large amounts of diuretics will cause hypokalemia plasma disorder, and kidney function and blood ions need to be checked regularly.

2. Receptor blockers, when taking receptor blockers, follow the principle of small doses and long-term use. Do not increase or decrease abruptly.

3. Calcium channel blockers, the drugs that can be selected are nifedipine and amlodipine besylate, and it is recommended to use sustained-release agents, not short-acting calcium channel antagonists.

4. Angiotensin-converting enzyme inhibitors, also known as ACE inhibitors, can effectively prevent, stabilize and delay the damage of hypertension to the kidneys.

5. Patients with malignant renal arteriolar sclerosis, if the renal function deteriorates rapidly in a short period of time, and there is an acute hypertensive crisis such as hypertension, the drug nitroprusside can be given intravenously.

Hypertension combined with renal impairment requires patients to use some drugs that do not damage the body's kidney function and are metabolized in the human liver, so it is necessary to start from a small dose and gradually increase the dose to protect the human body's kidney tissue. Patients also need to pay attention to personal diet, pay more attention to adjusting personal living habits, do not stay up late, and participate in more sports.

Hypertension will cause renal function decline in the later stage, in fact, renal function decline will aggravate the heart with high blood pressure, so it will enter a vicious circle, so we must pay special attention to hypertension combined with renal impairment in the selection of antihypertensive drugs, the following we will introduce in detail how to choose antihypertensive drugs for patients with hypertension and renal insufficiency, I hope it will be of some help to friends.

If hypertensive patients are combined with the phenomenon of damage, the main reason is that they need to choose some sufficient drugs to control the symptoms, and they need to start from a small dose and gradually increase the dose, and the antihypertensive drugs need to be metabolized in the liver to avoid certain harm to the kidneys, and will not affect the kidney function without reducing the renal blood flow.

ACE inhibitors, angiotensin receptor blockers, calcium channel blockers, receptor blockers, 1-receptor blockers, diuretics, vasodilators, indapamide or methyldopa, these drugs are actually very effective.

If it is very severe renal failure, patients with hypertension need to use some vasodilator drugs, and patients can be given 1-receptor blockers, which can effectively dilate arterioles and venules without affecting renal blood flow and kidney function. Patients may be given prazosin (mainingpin), terazosin (Gautrin, masanil), and doxazosin (Biazin). In renal failure, 1-blockers should also be reduced.

Hydralazine does not affect kidney function, but it tends to cause fluid retention.

Renal hypertension, which is mainly due to increased blood pressure caused by renal parenchymal lesions and renal artery lesions, is called renal hypertension in symptomatic hypertension. Renal hypertension is a type of secondary hypertension that is mainly due to increased blood pressure due to renal parenchymal lesions and renal artery lesions. The occurrence of this disease is mainly due to glomerular vitreous degeneration, hyperplasia of interstitial tissue and connective tissue, tubular atrophy, and narrowing of renal arterioles, resulting in both substantial damage to the kidneys and insufficient blood; The mid-layer mucinous muscle fibers of the renal artery wall proliferate, forming most small aneurysms, causing the inner wall of the renal arterioles to protrude in a bead-like manner, resulting in segmental stenosis of the renal arteries. nonspecific Takayasu's arteritis, which causes renal hypoperfusion; Under the combined effect of the above factors, it leads to the occurrence of hypertension.

Hypertension will cause kidney damage, and the two promote each other and will further develop the disease, so it is necessary to be active in renal hypertension. The ** of renal hypertension mainly includes the following aspects: 1. ** drug selection of renal hypertension:

For the pathogenesis of renal hypertension, in terms of drug selection, any drug that can reduce renin release or inhibit angiotensin-converting enzyme, or can dilate the renal artery, improve the blood and oxygen supply to the kidneys, and reduce blood volume can play a role in reducing renal hypertension. There are several drugs commonly used for **renal hypertension: (1) Diuretics, generally thiazides, if the kidney function is obviously impaired, loop diuretics should be selected, such as furosemide and butylureamine.

2) Calcium antagonists, which reduce peripheral resistance by reducing the concentration of intracellular calcium, do not affect cardiac output, and will not lead to sodium and water retention when applied for a long time, and even have a diuretic effect, such as nifepyridine, Baixintong, Luohuoxi, etc. (3) Receptor blockers, adrenergic receptor blockers, can inhibit renin secretion, and have a good effect on hyperreninic hypertension, such as propranolol, aminoyl propranol, medo propranol, etc. (4) Drugs that improve the blood supply and oxygen supply to the kidneys and reduce the release of renin, such as hydralazine, dihydralazine, long-pressure determination, etc.

5) ACE inhibitors, such as captopril, enalapril, perindopril (Yashida), phenaprila (lotincin), etc. (6) Drugs that inhibit renin activity, such as clonidine, methyldopa, etc. 2. Adrenovascular hypertension

Percutaneous renal angioplasty, surgical revascularization, and medications can be selected depending on the condition. The purpose is not only to lower blood pressure, but also to protect kidney function. Surgeries** include kidney transplantation, revascularization, and nephrectomy.

It should be noted that ACE inhibitors and angiotensin-type receptor blockers are contraindicated in patients with bilateral renal artery stenosis, impaired renal function, or poor renal function on the non-stenotic side, because these drugs relieve the constriction of the ischemic glomerular arteries, reduce the pressure in the glomerular sac, and worsen renal function.

Hypertension is a common disease, genetic factors are one of the factors that lead to hypertension, and diet, weight, medications, etc. may also lead to hypertension. Control blood pressure Get rid of bad habits in life How to face the perseverance of the three virtues correctly

After the occurrence of hypertensive kidney damage, the application of antihypertensive drugs is to protect the residual nephron and delay the development of renal damage, so drugs that can delay the deterioration of renal function and protect the nephron should be preferred, such as ACE inhibitors (xx pril) and ARB (xx sartan). ACE inhibitors are one of the most effective drugs to protect the kidneys, and they are particularly effective in delaying the development of renal damage. Compared with ACE inhibitors, ARB drugs have fewer adverse reactions and better safety in hypertensive kidney damage.

However, it is still necessary to judge the medication according to its own test value, and some patients with renal insufficiency are contraindicated to ACE II drugs, such as bilateral renal artery stenosis or one kidney with renal artery stenosis.

In addition to drugs**, hypertension combined with kidney disease should also pay attention to more diet and lifestyle, control the amount of salt, reduce fat intake, moderate exercise, quit smoking and limit alcohol, maintain a happy mood, avoid tension, stress and so on.

How to choose antihypertensive drugs for renovascular hypertension? The doctor tells you the answer.

At this point, it is difficult to say, measure blood pressure constantly, and take ordinary blood pressure medication to work. It doesn't work, it's mainly renal hypertension, which is caused by kidney disease, so let the doctor prescribe some medications. In fact, blood pressure will return to normal after a kidney transplant. You can refer to the following (Zhou Sanshan's peace and enjoyment).

Hello, it is recommended that you use long-acting preparations of traditional Chinese medicine litencin drug peaceful, long-lasting effect, no *** and dependence, with ideal curative effect, headache, dizziness, tinnitus and backache and leg pain caused by high blood pressure has a good relief effect, can also soften blood vessels, remove blood garbage, increase the elasticity of microvessels, prevent blood vessel rupture, prevent hypertension complications, and can play a role in protecting target organs such as heart, brain and kidney.

It can be combined with Catalpa grass conditioning and brewed with boiling water to make tea, which has the effects of anti-inflammatory and antibacterial, clearing heat and detoxifying, regulating blood pressure, preventing cardiovascular and cerebrovascular diseases, and enhancing immunity and resistance.

Dietary Considerations:

Limit the consumption of foods that contain high cholesterol, such as the brain, liver, heart, caviar, fatty meat, pork, butter, bone marrow, etc. of carnivores. The total amount of cholesterol consumed per day should be less than 300mg. If lipids are persistently high, foods high in sugar should also be limited.

Some foods contain protein that can inhibit the absorption of cholesterol. For example, soy products contain a special nutrient - sitosterol, which can inhibit the absorption of cholesterol in the small intestine, and patients are very beneficial to eat soy products regularly.

Always pay attention to eating more vegetables and fruits, which are rich in vitamins and contribute to the function of lipid metabolism. In addition, honey, jellyfish, sea cucumber, coconut white, celery, vinegar, wolfberry, water chestnut, etc. have a certain effect on lowering blood pressure.

On the one hand, patients should pay attention to food and nutrition, and on the other hand, they should pay attention to cooking methods, and it is better to process foods and decoctions that are light. Foods with high sodium salt, such as pickles, mustard, pine eggs, bacon and ham, can increase the sensitivity of blood vessels under the action of endocrine, cause spasm of arteries, and increase blood pressure. Therefore, foods containing sodium salt should be eaten sparingly.

At the same time, alcohol consumption should be appropriately limited, and it is not advisable to avoid alcohol altogether.

Angiotensin receptor antagonists can be used to control most of the drugs that end in sartan.

What medicine is good for hypertensive nephropathy? For hypertensive nephropathy, it is mainly carried out through drugs, but many patients with hypertensive nephropathy do not know much about what drugs to use and how to take them

Diuretic; receptor blockers; calcium antagonists; Angiotensin-converting enzyme inhibitors (ACE inhibitors). Among them, calcium antagonists and ACE inhibitors are more beneficial to the hemodynamics of the kidney, and ACE inhibitors are better than other antihypertensive drugs in reducing urine protein. Effective control of blood pressure to normal or near-normal can prevent, stabilize or delay hypertensive kidney damage.

Patients with malignant renal arteriolar sclerosis have rapid deterioration of renal function in the short term, and when they are combined with hypertensive encephalopathy, rapid vision loss, intracranial hemorrhage, etc., and cannot take oral drugs, they can be administered intravenously, and nitroprusside sodium is commonly used to control blood pressure in 12 to 24 hours. Long-pressure can rapidly lower blood pressure and is suitable for the initial stage of malignant hypertension**.

Patients with hyperlipidemia, diabetes mellitus and hyperuricemia should be given corresponding **. Concomitant use of antiplatelet aggregation and adhesion drugs, such as dipyridine and aspirin, may have the effect of preventing renal arteriole sclerosis.

To keep the stool smooth, it is advisable to use Qingning pills and Mojia Qingning pills. Traditional Chinese medicine should be used with Bupleurum citrus orange soup, gastrodia hook vine drink, etc. Nephropathy** must be carried out in a regular nephrology hospital. Nephrology Consultation**: 1528421392

Dr. Zheng