What is objective response rate, what does objective response rate mean in pharmacy

objective response rate.

It is based on the response rate that is objectively measured, such as changes in tumor size, changes in blood test indicators, etc. This is in contrast to the Lord's view of the elderly (i.e., the patient's own feelings or the doctor's careful observation of the patient's signs). In general, the confidence level of ORR is relatively high, while the reliability of patient or physician feedback is relatively low.

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Objective Probability and Subjective Probability 1 Objective Probability and Subjective Probability Theory is a theory that studies the regularity of the number of random events, and its basic concepts are random events, random variables, and related probability and probability distribution. In general, the probability and distribution determined by a random trial are called objective probabilityObjective probability reflects the objective nature of things, and it does not vary according to the factors of the decision-maker, that is, it has nothing to do with the individual interpretation of the decision-maker.

An important feature of objective probability is that it is defined by a large number of repeated trials, or by the ratio of events to populations in a finite set.

However, in actual management activities, people are often required to estimate the likelihood of these events and make decisions based on the estimated likelihood. This requirement leads to the formation and application of the concept of subjective probability. Subjective probability, personal probability, is an opinion, a measure of reasonable belief.

This is a measure of someone's belief (or opinion, perception) about the likelihood of a particular event occurring, i.e., the likelihood that he thinks the event will happen. Subjective probability: A number between 0 and 1 is used to describe the probability of an event occurring, based on a personal subjective judgment about whether an event occurs and how likely it is to occur.

Subjective probability reflects the subjective properties of things, and its determination allows to be related to the subjective individual interpretation of the decision-maker. It is set by the decision-maker's empirical knowledge and understanding of the objective situation, and the use of relevant information for analysis, reasoning, and comprehensive judgment, not subjective speculation. The definitions of subjective probability and objective probability reflect two different philosophical perspectives, namely the subjective probabilists (Bayesians) and the objective probabilists (non-Bayesians).

Objective probabilists believe that probability is an intrinsic objective property of a system, the limit of frequency when repeated under the same conditions.

The judgment method is different: the correctness of the subjective probability cannot be tested by experimental or statistical methods, but the correctness of the objective probability can be tested by experimental or statistical methods.

The objects are different: subjective probability cannot be used for fully repeatable events, and objective probability can only be used for fully repeatable events.

The nature is different: the subjective probability is the nature of the observer, and the objective probability is the intrinsic objective property of the system.

Interrelationship: Together, they complete the probability estimate.

4. Relationship between objective and subjective1

First, let's introduce the concepts of objective response rate and overall response rate:

Objective response rate (ORR) refers to the proportion of patients whose tumors shrink to a certain amount and remain for a certain period of time, including CR+PR cases.

Overall response rate (ORR): The proportion of the total number of patients who have undergone a complete response and a partial response to the total number of evaluable cases in solid tumors** studies. It is equal to the sum of the number of complete and partial response cases (CR+PR) divided by the total number of evaluable cases.

The specific differences are as follows:

1. Consider different situations.

The objective response rate considers the prognosis status, and then the ** interval, this indicator is directly related to the prognosis of the patient, when the patient's prognosis is poor, only the disease status during the maintenance period can be assessed.

The overall response rate is that the patient only needs to reach CR and PR after **, and whether there are high-risk factors that cause the interval between patients to be shorter and shorter is not analyzed.

CR (complete remission): disappearance of all target lesions.

PR (Partial Response) :p R: 30% reduction in the sum of the length and diameter of baseline lesions

Objective response rate (ORR) refers to the proportion of patients whose tumors shrink to a certain amount and remain for a certain period of time, including CR+PR cases.

Overall response rate (ORR) is the proportion of the total number of patients with CR+PR to the total number of evaluable cases.

But I still can't believe it.

Be objective. Probability, also known as probability, chance, probability, or probability, is a basic concept in probability theory.

Probability is a measure of the probability of a random event occurring, and is generally expressed as a real number between 0 and 1 to represent the probability of an event occurring.

First of all, probability is objective.

Then you mentioned the problem of drawing lots, there is no difference between catching and catching later, but the difference between this and tossing a coin is that each coin toss is an independent event, and the situation of your next toss has nothing to do with the previous one.

But the several tests before and after the draw are related, which involves the conditional probability, such as 2 tickets, one with a prize and one without, no matter who is first, the probability of winning the lottery is 50%, but the person who draws first looks at the result and does not look at the result, has no effect on the statistical result of the probability of winning the lottery of two people.

For A---B, the percentage of this change in A compared to the No change in A is the conversion rate.

The ratio of the actual reaction of the reactants to the original! eg: If you go from A to B, the amount of A is 1, and if some A is converted into B, then the conversion rate is.

(All of the converted)*100% (as long as the upper and lower units are the same).

For example, in the ammonia synthesis reaction, there is a mol H2 in total, and B mol is reacted, then, the conversion rate of H2 = (b a)*100%.

is the ratio between the amount that has been transformed and the mass of the original substance.

For example, if you go from A to B, the amount of A is 1, and if some A is converted into B, then the conversion rate is.

Chemical conversion rate.

Conversion rate = converted from raw materials.

BAI amount Total amount of raw materials * 100%.

1: The ratio of the reaction rate of each substance in the chemical equation zhi is equal to the ratio of their stoichiometric numbers.

2: The reaction rate of each substance in the chemical equation indicates the same chemical reaction rate, and the conversion rate generally refers to the chemical conversion rate: the chemical conversion rate is the mass of the substance participating in the reaction The total mass of the substance.

Subjective questions are those that better test the specific situation or personality of the student. Through the examination of such test questions, it is possible to fully understand the degree of understanding and mastery of a specific part of a certain course, and can test the ability of students to accurately recall what they have learned, flexibly organize materials, express problems clearly, and deeply understand the essence of the problems.

Objective questions are questions that allow candidates to identify the correct answer from a pre-prepared answer. The question types include true/false, multiple-choice, matching, etc. Objective questions are also called fixed response test questions, and the test papers with objective questions have sufficient coverage, and the marking and scoring completely avoid the interference of the subjective factors of the markers, and can also improve the efficiency of marking through machine marking.

Subjective questions are those that better assess the specific situation or personality of the student.

Objective questions are questions that allow test takers to identify the correct answer from a pre-prepared answer.

Subjective Question Advantages:

1. It can fully understand the degree of students' understanding and mastery of a specific part of a course.

2. It can test students' ability to accurately recall what they have learned, flexibly organize materials, express problems clearly, and deeply understand the essence of problems.

Advantages of objective questions:

1. The flexibility of the proposition is large.

2. Wide coverage of knowledge.

3. The accident of the examination content is small.

4. Strong objectivity and fast speed of collection.

The college entrance examination and high school examination questions are divided into two parts, one is multiple-choice questions, that is, each question gives candidates three, four or more answers, and students are required to choose the answer that meets the meaning of the question. This type of test is an objective test. The correct answers to these questions are the same.

The second part is to give some materials and questions, and ask students to analyze the questions according to what they usually learn, and give reasonable answers after their own arrangement. This type of test is subjective. The answers written in this type of test in the United States are not necessarily exactly the same, and they are affected by their own subjective will.

Subjective questions need to be combined with your knowledge and organized language to answer. Objective questions, on the other hand, have a predetermined question setting, and you only need to choose the answer from the predetermined answers.

Subjective questions are questions that can be answered according to one's understanding of the question, and there is no standard answer. Generally refers to questions that are not multiple-choice.

An objective question is a question that has a standard answer, and you will only be scored if your answer is the same as the standard answer. Generally refers to multiple-choice questions.

There is no standard answer to subjective questions, and points can only be judged from the central idea and the basic principles of answering. Objective questions generally have a single standard answer, and points can only be judged based on this unique standard.

Subjective questions are questions that don't have standard answers, and objective questions are questions that have standard answers.

Subjective questions are writing questions such as question and answer questions, big questions.

Objective questions are multiple-choice questions.

To put it simply, choice is an objective question, and what is described in language is an objective question.