What is hyperdifferentiation of cells ?

To put it simply, the degree of differentiation is too high.

Cell differentiation refers to the process by which the offspring produced by one or a type of cells are stable in morphology, structure, and physiological functions.

Tumor cells are very different in morphology and structure, and they are characterized by overdifferentiation compared to normal cells, such as fibrosis, calcification, or ossification, which we call overdifferentiated.

Tumor cells are very different in morphology and structure, and they are characterized by overdifferentiation compared to normal cells, such as fibrosis, calcification, or ossification, which we call overdifferentiated.

The direct cause is superficial, the protein is different, the traits and functions of development are also different, resulting in different structures, so it is cell differentiation, and in essence, it is "the same genetic material, the selective expression of genes", that is, the expression of DNA is different, the synthesis of different RNA and then the synthesis of different proteins, from the source, the universal life phenomenon in the biological world, is the basis of biological ontogeny. Specializing the cells of multicellular organisms is conducive to improving the efficiency of various physiological functions. High efficiency of various physiological functions.

The relationship between differentiation and cytoplasm can be discussed from the ooplasm. For example, after fertilization of Paracaris equigue, all chromosome-reduced cells develop into somatic cells (see Germplasm). The distribution of cytoplasm in the eggs of many animals has a clear regionality.

Although this regionality does not affect the behavior of chromosomes, it plays a decisive role in the later development of embryonic organs. <>

In cell differentiation, the nucleus plays a decisive role. It is thought that the nucleus contains the complete set of genetic information about the organism. When conditions are right, it can allow the cells to develop and differentiate into complete individuals composed of various types of cells.

Cells that have fallen off from the tissue clumps formed by small pieces of the pith of cultured tobacco can be isolated and cultured individually to obtain young shoots with roots and leaves, and then transplanted into the soil to grow flowering plants. In amphibians, transplanting the nuclei of blastocysts and early gastrulations into eggs that have been removed in advance can make the eggs develop normally, indicating that the nuclei of animal and plant somatic cells are totipotent. The regulation and control of gene expression in cell differentiation is a very complex process, and there are regulatory mechanisms at all levels of protein synthesis, from mRNA transcription, processing to translation.