Is high uric acid a kidney insufficiency Is high uric acid a kidney insufficiency

Renal function indicators include urea nitrogen, creatinine, and uric acid, which can only reflect a part of glomerular filtration, and creatinine is mainly observed. High uric acid does not necessarily nephrofunction, but uric acid tends to be elevated in renal insufficiency. Because uric acid is related to dietary intake and urine excretion.

In patients with renal insufficiency, glomerular filtration is reduced, tubular reabsorption is impaired, and uric acid excretion is also affected. Therefore, most patients with chronic renal insufficiency have hyperuricemia. If uric acid is only high, it can be corrected with diet and medication. "

The cause of high uric acid caused by the food eaten only accounts for about 10% of the entire effect, and nearly 90% of the uric acid is metabolized by the body itself. Every day, the uric acid that we metabolize is excreted through the urine and intestines. Of these, 70% is excreted in urine and 30% through the intestines.

This excretion is balanced with the uric acid produced by the body. That is to say, the quality of kidney function directly determines 0% of uric acid discharge, and the quality of intestinal tract determines 30% of acid discharge. The effect of food on uric acid accounts for only 10%.

Therefore, the main cause of high uric acid is kidney function problems, followed by gallbladder and constipation. The effect of food is that after you have already developed high uric acid, you start to try everything you can to find possible factors in various parts.

Therefore, after uric acid is high, we have to eat a low-purine diet to limit the rise of uric acid, generally we divide foods into several categories: purine content is 0-30mg, 30-75mg, 75-300mg, 300-600mg, 600mg or more. The lower the purine, the better the control of uric acid

Analysis: Hello! High uric acid does not necessarily mean renal insufficiency; But renal insufficiency will certainly increase uric acid.

Guidance: High uric acid is generally caused by purine metabolism disorders, which can cause gout. Impaired excretion can cause elevated uric acid (not necessarily metabolically produced excess uric acid) when renal dysfunction occurs.

Elevated uric acid is related to the kidneys, and hyperuricemia is a metabolic disease caused by purine metabolism disorders. When hyperuricemia occurs, some patients can have uric acid nephrolithiasis, which accounts for about 10%-25% of hyperuricemia, and patients can have uric acid stones, which are sediment-like, usually without symptoms, and those with larger stones can have renal colic and hematuria. When stones cause infarction, it is easy to cause hydronephrosis, pyelonephritis, pyometraphrosis or perirenal inflammation, and severe patients can lead to acute renal failure, and infection can accelerate the growth of stones and damage to the renal parenchyma.

When hyperuricemia occurs, it needs to be treated, and acid excretion drugs, antacids, and analgesics should be given, and patients should check the level of uric acid frequently, try to keep uric acid within the normal range, and avoid causing damage to the kidneys.

1. If uric acid is high, is there a kidney problem? This is not absolute, and most patients with high uric acid have normal kidney function.

2. When will abnormal kidney function occur? When gouty nephropathy occurs, when high uric acid lasts for a long time, this will affect kidney function. But even if the kidney function is normal now, it cannot relax**.

Because if your uric acid can't be controlled, sooner or later there will be abnormal kidney function, and it will be more troublesome at that time.

3. Therefore, the concept of treating gout now is to dissolve crystals, protect the kidney, and regulate metabolism. It is not only to lower uric acid, but also to protect our kidney function, and at the same time to keep the uric acid lowered. A system is more useful than you blindly for several years.

High uric acid. It has something to do with the kidneys. The final product of purine metabolism is mainly uric acid, when purine metabolism is disordered, resulting in excessive production of blood uric acid or decreased uric acid excretion, the blood uric acid concentration can be increased.

When urate is supersaturated in the blood, it can be precipitated and precipitated in the kidney, causing kidney damage and becoming hyperuricic acid nephropathy.

Renal manifestations of hyperuricic acid nephropathy:

1.Chronic gout.

Nephropathy: nephropathy is independent of the severity of gout, with a slow onset and early microscopic hematuria or mild proteinuria.

Intermittent, some manifestations are gross hematuria, mild edema, and moderate hypertension. The pathology is predominantly interstitial nephritis.

2.Urate Acid Stones: Pure uric acid stones can cause hematuria, ureteral obstruction, and secondary urinary tract infections.

The course of the disease can be prolonged for more than 10 years.

3.Acute hyperuric nephropathy: uric acid increases sharply, and a large number of crystals are deposited in the collecting ducts, calyceses, renal pelvis, and ureters, resulting in a sudden decrease in urine and the formation of oliguria, acute renal failure.

High uric acid has nothing to do with the kidneys, mainly seen in primary purine metabolism abnormalities, such as hyperuricemia, gout, and environmental factors, such as a high-purine diet can also lead to an increase in uric acid, as well as enzyme abnormality diseases, such as xanthine, guanine, transamide ribosylkinase deficiency, and secondary purine synthesis problems, such as glucose-6-phosphate dehydrogenase deficiency. In addition, there may also be drugs, such as diuretics, tumor chemotherapy drugs, phenytoin, methyldopa and other drugs may also cause uric acid to rise, so high uric acid may or may not be related to the kidneys. Of course, uric acid may also be related to the kidneys, such as common renal dysfunction, such as chronic nephritis, renal insufficiency will lead to an increase in uric acid.

High uric acid is related to the kidneys, because the excretion of uric acid is mainly through the renal tubules, and if there is a lesion in the kidneys, it will lead to an increase in uric acid in the body, which will cause gout. After the appearance of gout, it is still necessary to actively lower uric acid**.

1. The kidneys are not good.

Under normal circumstances, poor liver function will not lead to high uric acid in the human body, and high uric acid and liver insufficiency are two different things and are not directly related; However, kidney function may cause high uric acid in the body.

Generally, there are two main reasons for high uric acid in the human body, one is excessive uric acid synthesis in the body, which is generally related to the abnormal metabolism of enzymes in the body, and the other is the decrease in uric acid excretion, which is common in acute and chronic glomerulonephritis, renal failure, etc.

2. Under normal circumstances, the only symptom of hyperuricemia is increased skin and trillion acid in the blood urine, but if it is not carried out in time**, then the patient may develop gout, which may lead to acute arthritis and tophi in the human body; Secondly, most patients are accompanied by metabolic syndrome such as obesity and type 2 diabetes.

If serum uric acid fluctuates or persistently increases in patients with hyperuricemia, only elevated serum uric acid is found in patients with asymptomatic hyperuricemia; About 5% to 12% of patients with hyperuricemia eventually develop gout, leading to gouty arthritis, interstitial nephritis, and tophi formation; In severe cases, joint deformity or uric uric tract stones appear; Finally, more patients have associated symptoms such as obesity, elevated blood glucose, dyslipidemia, hypertension and arteriosclerosis.

3. Generally, no.

Under normal circumstances, high uric acid is mainly caused by high purine content in the human body, and it is necessary to avoid foods with high purine content at this time; At present, there is no clear data in medical research that drinking tea will cause high uric acid, and drinking tea will not cause the human uric acid to rise, but it is better not to drink strong tea if the uric acid is high.

4. In general, patients with hyperuricemia need to abstain from alcohol in their diet, especially beer, which can easily induce or aggravate the symptoms of hyperuricemia.

Foods with high purine content include animal offal, bone marrow, seafood, etc., which are rich in purines; Fish and shrimp, meat, peas, spinach, etc. also contain certain purines; Fruits, vegetables, milk, eggs, etc. do not contain purines.

Orthohyperuricemia is an abnormal purine metabolism in nucleic acids, resulting in excessive uric acid production or decreased excretion, resulting in a persistent increase in the level of uric acid in the blood. About 2 3 free uric acid in the body is excreted by the kidneys, and uric acid is deposited in kidney tissue, causing hyperuricemia nephropathy (uric acid nephropathy).

Dietary precautions for high uric acid:

1) Drink more water and less soup. (2) Eat more alkaline foods and less acidic foods. (3) Eat more vegetables and eat less.

Generally speaking,High uric acid does not necessarily mean kidney disease, but kidney disease can cause high uric acid in most cases。There is a causal relationship between them, but there is no necessary connection.

That being the case, what exactly causes high uric acid? It's actually quite simpleIn most cases, it is closely related to our living habits

1. Caused by eating too much purine food. High-purine foods, long-term eating or eating too much at one time, resulting in a large production of uric acid can not be excreted from the body in time, resulting in an increase in the amount of uric acid in the body.

2. The patient's uric acid function decreases. The decrease in uric acid excretion is a pathological manifestation of high uric acid. The cause of high uric acid is caused by diseases, most of which are due to the decline of kidney function, and it is common for the renal tubules to clear uric acid when the excretion function decreases, resulting in inexhaustible uric acid discharge and high uric acid value.

3. Irregular life factors. Irregular lifestyle and diet can lead to high uric acid value, similar to this situation is not very serious, patients only need to improve their good diet, you can restore uric acid value in a short period of time, generally does not need to carry out **. Long-term high uric acid will not only lead to the appearance of gout, but also cause certain damage to the patient's kidneys and other metabolism, so it is necessary to control the phenomenon of high uric acid in time.

WhileRegarding the high uric acid, in fact, it is necessary to start with lifestyle habits, such as:

1.Drink plenty of waterKeep 1500 3000 ml a day, drink a small amount and drink it many times to help the excretion of uric acid.

2.Prohibition of alcohol,Alcohol is easy to accumulate lactic acid in the body, has an inhibitory effect on uric acid excretion, and is easy to induce gout; Alcohol is strictly abstained, and beer and seafood are absolutely prohibited. Beer itself contains alcohol, which can affect the excretion of uric acid; Moreover, during the oxidation of alcohol, some substances will be produced to increase uric acid.

Seafood contains purines and proteins, and a large intake of protein will put our body in a slightly acidic environment, which will promote the formation of uric acid crystals; In addition, a large amount of purines will cause a sharp increase in uric acid due to a large intake of seafood in a short period of time. Although our dietary factors only account for 10 20 of uric acid, eating a large amount of seafood in a short period of time leads to a sharp increase in uric acid, and drinking alcohol affects excretion.

Many people will have elevated uric acid in the examination of kidney function, most people think that the main reason for elevated uric acid is kidney disease, in fact, there are many reasons for elevated uric acid, so, what? The following is a detailed answer by experts for you! Hope it helps!

Experts point out that under normal circumstances, there are about 1,200 milligrams of uric acid in the body, and about 600 milligrams are newly produced every day, and 600 milligrams are excreted at the same time, which is in a balanced state. However, if the body produces too much and does not have time to excrete it or the uric acid excretion mechanism degenerates, the body retains too much uric acid. And what is going on with high uric acid should be correctly diagnosed so that it can be timely**.

Studies have found that high uric acid is also related to normal kidney function. All the uric acid in the blood is filtered through the glomeruli, of which 98% is secreted into the glomerular lumen in the middle of the proximal convoluted tubule, and then 50% of the reabsorbed uric acid is secreted into the renal tubule lumen in the middle of the proximal convoluted tubule, and 40% 44% is reabsorbed in the straight proximal convoluted tubule, and only 6% of the 10% uric acid is excreted. Elevated serum uric acid is common in gout, and high uric acid** is also associated with certain diseases, such as leukemia and other malignant tumors, multiple myeloma, polycythemia vera, etc.

The elevation of serum uric acid is more pronounced after tumor chemotherapy. In the setting of decreased renal function, it is often accompanied by an increase in serum uric acid. It can also be seen in kidney diseases such as acute and chronic nephritis, and in the advanced stages of other kidney diseases such as renal tuberculosis, pyelonephritis, hydronephrosis, etc.

The above is the reason for the increase in uric acid in kidney function, this time you will have a certain understanding of the cause of the elevated uric acid, understand the cause of the disease, and it is very helpful to carry out the disease as soon as possible!

Hello, high uric acid is the main cause of gout. It is recommended that you eat less foods high in purines, and you should first control your diet. First of all, foods containing very large amounts of purines are absolutely contraindicated:

Such as sheep's heart, pancreas, concentrated gravy, dried meat, fidle, sardines and yeast. Secondly, foods containing a lot of purines, such as anchovies, cod, salmon, mackerel, salmon, scallop fish, salted pork, goose, pigeon, beef, liver, kidney and pheasant. Eat as little as possible foods containing moderate amounts of purines, such as chicken, duck, lamb chops, pork, rabbit, brain, ham, tongue, organ meats (stomach and intestines, etc.), oysters, shrimp, eels, halibut, sour apples, kidney beans, lentils, mushroom or mushroom products, soy products, green beans, peas, spinach and peanuts.

What can I eat? It is suitable to eat the following low-purine foods: various dairy and cheese; eggs; cereals, such as bread, polenta, noodles; Vegetables, all varieties except those that account for a moderate amount of purines; lipids, various fats (moderate intake), creamy products and butter; nuts, such as walnuts, chestnuts; colloids, such as sea cucumbers and shark fins; concentrated vitamin products, such as cod liver oil; beverages such as tea, coffee, juices, soft drinks, chocolate and cocoa tea; Other classes such as caviar, sugar, honey, pies, etc.

As long as the above dietary principles are followed and persistent, most patients can achieve the goal of lowering blood uric acid and reducing gout attacks.