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The early symptoms of scleroderma are mainly manifested as whitening, redness, purple, muscle tenderness, joint pain, numbness, swelling, erythema, muscle weakness, edema, itching, stereotyped face, inability to clench fists with both hands, morning stiffness of finger joints, cyanosis, finger movement disorders, unable to be lifted normally, hardening, texture fading and other symptoms, and if the situation is serious, it will also cause lesions of the kidneys, heart and lungs, and even life-threatening if it is not timely.
Scleroderma is generally caused by factors such as abnormal humoral immunity, congenital heredity, abnormal hormone secretion levels, environmental influences, etc., early scleroderma can be treated with some drugs that dilate blood vessels and improve microcirculation, such as aspirin, dipyridamole, etc., and can also be improved with some drugs such as glucocorticoids or immunosuppressants, such as methotrexate, cyclohorin, etc., and you can also eat some drugs that can increase nutrition and elasticity, such as penicillamine, Usually pay attention to keep the best clean and hygienic, but also do a good job of keeping yourself warm, which is helpful for diseases.
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1.The key difference between the two is: Are there any other manifestations of system damage? Are there autoantibodies?
2.Systemic sclerodergy, also known as systemic sclerosis, is a connective tissue disease.
Usually with systemic multisystem injury, the presence of autoantibodies on ancillary examination.
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Most patients with localized scleroderma are manifested as thickening of the fingers and face, and some will be formed in all parts of the limbs, resulting in the appearance of thickening, and some are afraid of cold, and will also induce vascular diseases, such as vasospasm and so on.
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Localized scleroderma, also known as morphea, is a localized swelling that gradually appears with atrophy and hardening, mainly on the scalp and forehead, or the waist, abdomen and limbs. When the rash first arises, it is a pale red rash of various sizes or a slightly edema macule.
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Raynaud's phenomenon (i.e., when the extremities turn pale in cold and dry weather, and turn red when the blood vessels are re-opened) and harden and thicken.
Gastrointestinal tract: including dysphagia, acid reflux, low bowel movements, etc.
Lungs: Interstitial pulmonary fibrosis and pulmonary hypertension are the most common causes of death from systemic sclerosis.
Kidneys: The most serious is renal hypertensive crisis, which refers to sudden hypertension caused by vascular lesions, and leads to rapid deterioration of renal function, retinopathy, capillary hemolysis and hypertensive encephalopathy.
Heart: A few can have arrhythmia, heart failure, pericarditis, etc.
Musculoskeletal pain: Generalized arthralgia and morning stiffness are typical symptoms.
Malignancy: Patients with scleroderma have a higher risk of developing lung tumors than the general population.
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Scleroderma is an autoimmune disease of unknown cause, with **edema, pale or reddish, followed by **dryness, smoothness, thickening, hardening, thinning, hair loss, and intractable ulcers at the fingertips and joints as the main clinical features. The disease is limited and systemic, with the former being limited to ** and muscle damage, and the latter involving internal organs. The age of onset of scleroderma is more common in 20 to 50 years, and it is more common in women than in men Scleroderma**.
The prognosis is good in patients with localization, and the prognosis is poor in systemic patients with rapid deterioration of the condition once the lungs, heart, and kidneys are affected. Scleroderma belongs to the categories of "muscle paralysis" and "skin paralysis" in traditional Chinese medicine.
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Hello Problem Analysis: What is scleroderma.
Guidance: Scleroderma is an autoimmune disease with fibrosis and blood vessels and internal organs. The severity of the disease varies widely, with some patients having localized benign skin lesions called scleroderma, and others having extensive skin lesions involving internal organs called diffuse systemic sclerosis
I wish you good health.
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