What is the shorthand for the eukaryotic mRNA hat structure?

Why don't you flip through a book if you ask such a question?!

Biochemistry (Shen Tong 3rd Edition).

Genetics Cell Biology (Renkyosha).

Eukaryotes' mRNA has a 5' cap and a 3' poly A tail;Eukaryotic mRNA generally exists in the form of monocistronic mRNA; Half-life of eukaryotic mRNA.

Longer; The mRNA precursors transcribed by eukaryotes need to be processed into mature mRNA that binds to proteins to form information bodies before they begin to work.

mRNA generally refers to messenger RNA

Messenger RNA is a class of single-stranded RNA that is transcribed from one strand of DNA as a template and carries genetic information to guide protein synthesis.

After mRNA is transcribed according to the principle of base complementarity pairing, the mRNA contains DNA molecules.

The base sequences corresponding to certain functional fragments are used as direct templates for protein biosynthesis. Although mRNA accounts for only 2% to 5% of the total RNA in the cell, it is the most diverse and metabolically active, and it is the RNA with the shortest half-life, which is broken down within minutes to hours after synthesis.

The processing of mRNA varies widely among eukaryotes, bacteria, and archaea. Essentially, non-eukaryotic mRNA is mature at the time of transcription and does not require processing except in rare cases. However, eukaryotic pre-mRNA requires a lot of processing.

5' end plus cap: The 5' cap (also known as RNA cap, RNA7-methylguanosine cap, or RNAM7g cap) is a modified guanine nucleotide.

Shortly after the start of transcription it is added to the "front" of newly generated eukaryotic mRNA, i.e.5'Extremity. The 5' cap consists of a terminal 7-methylguanosine residue, which passes through 5'-5'- The triphosphate bond is linked to the first transcribed nucleotide. It is present for ribosomes.

Identification and protection of mRNA are critical.

3' end plus tail: refers to polyadenosine.

The acyl moiety is associated with the mRNA molecule.

of covalent ligations. In eukaryotes, most messenger RNA (mRNA) molecules are in 3'The ends are polyadenylated. The polya tail and the proteins that bind to it help protect the mRNA from degradation by exonucleases.

The 3' end tailing is also important for transcriptional termination, export of mRNA from the nucleus, and translation. mRNA in prokaryotes is also often tailed by the 3' end, but the poly(a) tail at this time facilitates rather than prevents the degradation of mRNA by exonucleases.

5'End "hat" structure function.

1) Stabilize the primary structure of mRNA, and prevent the only way for mRNA to be 5'- Hydrolysis by exonucleases;

2) Provide a signal for mRNA to recognize ribosomes, so that mRNA can bind to ribosomes more quickly, so as to improve the protein synthesis efficiency of mRNA.

3'Function of the end polya tail structure.

1) facilitates the transfer of mRNA from the nucleus to the cytoplasm;

2) it has an effect on the rate of protein synthesis;

3) It is related to protecting the stability of mRNA and maintaining the secondary structure of mRNA.

Cap structure refers to mature mRNA formed by post-transcriptional modifications in eukaryotes5'A special structure at the end, the M7GPPPN structure, is also known as the methylguanosine cap.

1. Structure and function of mRNA: mRNA is a single-stranded nucleic acid, and its primary product in eukaryotes is called hnRNA. Most eukaryotic mature mRNA molecules have a typical 5'-terminal 7-methylguanosine triphosphate (M7GTP) cap structure and a 3'-terminal polyadenylated polyatriphosphate (PolyA) tail structure.

2. The function of mRNA is to provide a template for the synthesis of proteins, and the molecule carries the genetic code. Every three adjacent nucleotides in the mRNA molecule form a group that represents a specific amino acid in protein translation and synthesis, and this nucleotide triplet is called the genetic code (coden).

1 Eukaryotic mRNA has a 5' cap structure (M7G) and a 3' poly(A) tail (histidine).

No tail ha) fierce accompaniment

2 The pre-mRNA of eukaryotic cells has many introns (which will be spliced into mature mRNA translation).

3 The disadvantage of eukaryotic cells is that mRNA is mostly monocistron, that is, one mRNA encodes a polypeptide

4 Prokaryotic transcription is translated in one space (because there is no nucleus, but the eukaryotic ones are in different regions.)

5 Then there is the half-life.

The difference is that the prokaryotes are degraded very quickly, and most of the time they are translating while translating, and the eukaryotes are relatively slow.

First pass 5'-5'key to add a g to mRNA 5'Extremity.

1. The bit at the end of G plus a methyl group, and the one that only has such a single methyl group is called Cap 0 (cap), which all eukaryotes have.

2, 2 of the second base sugar chain'-o position plus a methyl group, with the above two methyl groups called cap1 (cap1), which is the most form of cap except for unicellular organisms.

3, the second base is methylated again, which is a rare event that occurs in eukaryotes, this methylation occurs only when this base is a, when it is methylated, n6 is methylated, and only when the sugar chain of a is 2'-o is already methylated.

4, when already with cap 1 (cap1), 2 of the third base sugar chain'-O is also methylated, which is cap-2 (cap2), which accounts for only 10%-15%.

mRNA of known eukaryotes class 15'The end has 7-methylguanosine-5'- Cap structure of triphosphate, 3'The end has a tail structure composed of polyadenylic acids.

Ask for advice, what kind of structural features does the hat structure and tail structure refer to? It is better to have **.

The mRNA cap structure in eukaryotic cells is ().

Methylguanine nucleoside triphosphate.

Methyluracil nucleoside triphosphate.

Methyladenine nucleoside triphosphate.

Methylcytosine n-oldidine nucleoside triphosphate.

Zhengqing Tan Sure Ye Sheng Answer: a