Is nifedipine controlled release tablets dependent, can I take it for a long time

Generally, it refers to the desire of the patient to continue using the drug after the patient has been using a drug for a long time and suddenly stops the drug, so as to avoid the discomfort caused by the discontinuation. So, is there a dependence on nifedipine controlled-release tablets? Can I eat it for a long time?

We know that nifedipine controlled-release tablets are well tolerated when combined with nitrates to control angina attacks; When used in combination with receptor blockers, the vast majority of patients have good tolerability and efficacy of this product, but individual patients may induce and aggravate hypotension, heart failure and angina; Combined with digitalis, it may increase the concentration of digoxin, suggesting that the blood concentration of digoxin should be monitored when using the product for the first time, adjusting the dose or stopping the product; When combined with drugs with high protein binding rate, such as dicoumarin, phenytoin, quinidine, quinine, warfarin, etc., the free concentration of these drugs often changes;Combined with cimetidine, the peak plasma concentration of the product increases, pay attention to adjust the dose;When grapefruit juice was taken with the product, the Cmax and AUC of the product increased.

Generally speaking, nifedipine controlled-release tablets are not dependent, so patients can take them for a long time. Of course, if the patient is still not at ease, he or she can consult a physician according to his or her own situation. Nifedipine controlled-release tablets are short-acting calcium antagonists, if you take it for a long time, a small number of people may produce symptoms such as flushing, headache, nausea, stomach discomfort, etc., and the single antihypertensive effect is unstable.

KangAiduo Pharmacy reminds you to pay attention to the toxicity of the drug when taking the drug to prevent its *** effect.

Nifedipine extended-release tablets and controlled-release tablets cannot be taken together, the two drug release processes are different, but they belong to the same class of drugs. According to the guideline recommendation: for patients with moderate or above hypertension or patients at high risk of hypertension, it is recommended to initially need a combination of drugs, that is, a combination of multiple drugs, such as nifedipine controlled-release tablets, plus angiotensin-converting enzyme inhibitors such as benazepril, or combined diuretics.

Choosing nifedipine sustained-release tablets and controlled-release tablets to take together may greatly increase the *** of this class of drugs, while the antihypertensive effect is not significantly enhanced.

Once the drug becomes dependent, the patient should continue to take it. So, can nifedipine controlled-release tablets be taken for a long time? Is it harmful to the body?

Nifedipine dilates coronary arteries, especially large blood vessels, and even healthy blood vessels in areas that are not completely blocked. Nifedipine also reduces the tone of the smooth muscles of the coronary arteries and prevents vasospasm. Ultimately, blood flow to narrowed blood vessels is increased, and oxygen supply is increased.

At the same time, nifedipine reduces the need for oxygen due to the reduced peripheral resistance (afterload). If taken for a long time, nifedipine can prevent the development of new coronary atherosclerotic lesions. Controlled-release tablets are a good preparation at present, which can gradually release a small amount of the drug, so that the blood drug concentration can be maintained at a constant level, so as to reduce blood pressure smoothly.

Extended-release tablets release the drug slowly, but there is no guarantee of constant release. Comparatively, the use of controlled-release tablets is safer and more effective, the incidence rate is relatively low, and the blood pressure can be more stable, so that the patient's blood can be kept within a safe range for a long time. Therefore, nifedipine controlled-release tablets can be taken for a long time without causing harm to the body.

At the same time, during the period of using nifedipine controlled-release tablets**, it is necessary to pay attention to a reasonable diet: limit fat intake. Eat foods that are rich in potassium and calcium, and low in sodium.

Limit salt intake. Eat protein in moderation and exercise more. If you have any questions, you can also go directly to KangAiduo Pharmacy for consultation, KangAiduo Pharmacy is committed to helping people improve the level of medication, reduce the cost of medication, and provide patients with direct supply from the manufacturer, low price, and absolute high-quality drugs.

Hello, there is a history of hypertension and hyperlipidemia, in this case, it is necessary to take nifedipine to lower blood pressure**, the drug controlled-release tablets can be taken for a long time, in addition, it is best to pay attention to diet, eat less greasy food and animal offal, avoid alcohol, and take hypolipidemic drugs such as simvastatin or lipibutal if necessary**.

Hypertension. There are many kinds, if the effect of taking nifedipine controlled-release tablets is not good, it may be that the medicine is not right, it is recommended to go to a professional hospital for examination in time, and it is not recommended to use the drug casually.

Taboo. This product is contraindicated in people who are known to be allergic to nifedipine or any of the ingredients in this product.

Nifedipine is contraindicated in cardiogenic shock.

Contraindicated in patients with KOCK sacs (ileostomy after rectocolectomy.

Due to enzyme induction, when combined with rifampicin, nifedipine does not reach an effective plasma concentration. Therefore, it should not be used in combination with rifampicin.

Nifedipine is contraindicated in 20 weeks of pregnancy and in lactating women.

Precautions. 1.For heart failure.

and patients with severe aortic stenosis, when the blood pressure is very low (systolic blood pressure [90mmHg severe hypotension, take this product, should be very cautious.

2.This product has a non-deformable substance, so patients with severe stricture of the gastrointestinal tract should be cautious when using this product, because symptoms of obstruction may occur. The occurrence of gastric stones is very rare and surgery may be required if they do**.

3.There have been anecdotal reports of obstructive symptoms in patients without gastrointestinal disease.

4.Line X-rays.

In barium swallow imaging, this product can cause false-positive results (mistaken for polyps due to filling defects.

5.Patients with hepatic impairment should be closely monitored, and the dose should be reduced if the disease is severe.

Calcium antagonists reduce the passage of calcium ions into cells through calcium channels. Nifedipine acts specifically on cardiomyocytes, coronary arteries, and smooth muscle cells in peripheral resistance vessels. So,?

Nifedipine controlled-release tablets are not suitable for every patient, and patients who do not have a good effect on nifedipine controlled-release tablets should decide whether to change the drug under the guidance of a professional doctor or pharmacist. The author reminds you that for patients with heart failure and severe aortic stenosis, when the blood pressure is very low (severe hypotension with systolic blood pressure <90mmHg), you should be very cautious when taking nifedipine controlled-release tablets.

Nifedipine controlled-release tablets have non-deformable substances, so patients with severe gastrointestinal strictures should be cautious when using nifedipine controlled-release tablets because of the possibility of obstructive symptoms. The precautions for taking nifedipine controlled-release tablets are mainly as follows: 1. For patients with heart failure and severe aortic stenosis, when the blood pressure is very low (severe hypotension with systolic blood pressure <90mmHg), you should be very cautious when taking nifedipine controlled-release tablets.

2. Nifedipine controlled-release tablets have non-deformable substances, so patients with severe gastrointestinal stricture should be cautious when using nifedipine controlled-release tablets, because obstructive symptoms may occur. 3. Patients with KOCK sacs (ileostomy after rectocolectomy) cannot use nifedipine controlled-release tablets. 4. When using barium swallow for comparative examination, nifedipine controlled-release tablets can cause false-positive results (mistaken for polyps because they fill the defect).

5. Pregnant women should be closely monitored if they are injected with magnesium sulfate intravenously at the same time. 6. Liver damage: patients should be strictly monitored with medication, and the dose should be reduced when the condition is severe.

7. The impact on the ability of the communicator and the ability to operate the machine: because the reaction to the drug varies from person to person, it may damage the ability to drive and operate the machine, and this effect is especially obvious in the early stage, when changing drugs and drinking. 8. Nifedipine controlled-release tablets have a non-absorbable shell, which can slowly release the drug into the human body for absorption.

When this process is over, empty tablets can be found in the stool. Broken tablets can cause early release of the drug, so it should not be taken, and the same should not be chewed or broken. The above is a brief introduction to nifedipine controlled-release tablets, I believe you have already understood.

I hope that everyone will use medicine scientifically and rationally according to their own needs.

Nifedipine controlled-release tablets cannot be taken for a long time, and long-term use will cause 1 common peripheral edema after taking the drug (peripheral edema is dose-related, the incidence is 4% when taking 60mg a day, and 120mg a day; Dizzy; Headache; Disgusting; Fatigue and facial flushing (10%). Transient hypotension (5%), most of which do not require discontinuation (transient hypotension is dose-dependent, with an incidence of congestive heart failure at 4% at dose; the incidence of pulmonary edema was 2%; The incidence of arrhythmias and conduction block is less than ever. 4 People who are allergic to this product may have allergic hepatitis, rash, and even exfoliative dermatitis.

1.Liver: Occasionally, jaundice and elevated glutamic acidacetate aminotransferase and glutamic acid acetonate aminotransferase.

2.Circulatory system: Occasional chest pain, headache, flushing, dizziness, palpitations, drop in blood pressure, edema of the lower limbs, etc.

3.Allergies: Occasional allergic symptoms such as measles and itching.

4.Digestive system: Occasional abdominal pain, nausea, loss of appetite, constipation, etc.

5.Oral: Gums may be hypertrophied.

6.Metabolic abnormalities: Occasional symptoms of hyperglycemia.