Cholangiocarcinoma? Bile duct carcinoma details

How long can you live for cholangiocarcinoma? How long you can live with cholangiocarcinoma depends on many factors, such as the patient's physical condition, and whether the patient has cholangiocarcinoma in the early or advanced stages. We all know that patients with early-stage cholangiocarcinoma can be effectively controlled if they can take effective measures in time, and the effect is also very significant.

Patients with early-stage cholangiocarcinoma can reach more than 90% through the regular **** rate, and the survival time can reach more than ten years or even decades.

Cholangiocarcinoma is much more difficult when it reaches the middle and advanced stages, and we all know that by the middle and advanced stages, cholangiocarcinoma is likely to have progressed and metastasized. Therefore, at this time, the difficulty will be very great, we must carry out it in a timely manner, the current medical technology is very developed, as long as we can actively carry out the disease, it is still possible to control the development of the disease and prolong the life of the patient, therefore, no matter what stage the patient's disease is in, it can be carried out.

Cholangiocarcinoma generally refers to intrahepatic cholangiocarcinoma, which originates from the secondary bile duct and its branch epithelial carcinoma, and the incidence is second only to hepatocellular carcinoma. In the early stage, there are no obvious symptoms, and there are three types: massive, bile duct invasive and intraductal growth type, and most patients lose the opportunity to undergo surgery, and can be diagnosed by liver puncture such as B-ultrasound, CT, magnetic resonance, and PET-CT.

Early symptoms of cholangiocarcinoma: There are no obvious symptoms of cholangiocarcinoma in the early stage, and it is generally jaundice, because cholangiocarcinoma will cause obstruction of the bile ducts, and after the bile duct is obstructed, bile cannot be discharged, and the symptoms of obstructive jaundice will appear. Patients have yellow eyes, yellow urine, etc., this obstructive jaundice is often the first sex, the patient is only yellow, generally not like the kind of obstruction of gallstones, which will cause obvious abdominal pain and fever, it often has no symptoms of abdominal pain and fever, only jaundice!

Cholangiocarcinoma is a type of primary liver cancer that occurs in the intrahepatic bile duct (i.e., above the first grade intrahepatic branch of the left and right hepatic ducts). Patients with cholangiocarcinoma may have symptoms such as epigastric discomfort and hepatomegaly in the advanced stage.

Cholangiocarcinoma is sometimes difficult to distinguish from hepatocellular carcinoma, and this dynamic is diagnostic. It should be distinguished from hepatocellular carcinoma and liver abscess.

Chinese name: Cholangiocarcinoma.

Clinical manifestations: In the late stage, there may be epigastric discomfort and hepatomegaly.

CT findings: low-density space-occupying lesions with irregular margins.

Differential diagnosis: It needs to be differentiated from hepatocellular carcinoma and liver abscess travel fiber.

Introduction, Imaging Findings, [**Pathology] Intrahepatic cholangiocarcinoma is a carcinoma that develops from the confluence of the left and right ducts of the liver (hilum of the liver) to the peripheral bile duct epithelial cells. Histologically adenoid differentiation or mucus secretion, fibrous interstitium, and harder than hepatocellular carcinoma. According to its location, it is divided into peripheral cholangiocarcinoma (intrahepatic cholangioma) and hilar cholangiocarcinoma.

Clinical manifestations] Clinical symptoms vary depending on the location of occurrence. Eggplant terminal cholangiocarcinoma is asymptomatic in the early stage, and may have epigastric discomfort, hepatomegaly, and weight loss in the late stage. hilar cholangiocarcinoma often presents with jaundice. CT findings:

1.Peripheral cholangiocarcinoma: noncontrast scan shows low-density space-occupying lesions with irregular margins, and the density is generally relatively uniform.

The contrast scan showed mild annular enhancement at the tumor margin in the early phase, a low-density ring at the tumor margin in the late phase, and a hyperdense ring in the center, and signs of intrahepatic bile duct dilation in the lateral branch of the tumor distal branch of the tumor tremor. Tumors less than 2 cm often do not show the above contrast-enhanced features, and only show a mild enhancement effect on the entire tumor. Sometimes it is difficult to distinguish from hepatocellular carcinoma.

In addition, **-shaped cholangiocarcinoma developing in the peripheral bile duct is often diagnosed only by the limited dilation of the peripheral bile duct, and attention should be paid to the differential diagnosis with intrahepatic bile duct stones. 2.Hepatic hilar cholangiocarcinoma:

On noncontrast scanning, the tumor is isodense with the surrounding liver parenchyma, and the intrahepatic bile duct is significantly dilated. Enhance the early phase of swelling to low density, about 10 15 minutes later, the tumor center shows high density. This dynamic has important diagnostic value.

When there is only intramural infiltration and no extramural intrahepatic mass has formed, CT enhancement only shows bile duct wall hypertrophy, which should be differentiated from chronic cholangitis. However, the thickness of the tube wall is uneven and the stiffness is different. [Differential diagnosis] should be distinguished from hepatocellular carcinoma and liver abscess.

The survival time of patients with advanced cholangiocarcinoma needs to be considered in combination with jaundice, as follows:

1. If the patient's jaundice is not resolved, it may be life-threatening within 1-2 weeks;

2. For patients with no jaundice, or low jaundice limitations, the survival time is generally 3-6 months, and the effective survival time can reach 1 year, or even more than 1 year.

Cholangiocarcinoma is a malignant tumor with a high degree of malignancy, and the overall survival rate is lower than that of other malignant tumors, such as gastric cancer, intestinal cancer, thyroid cancer, breast cancer, etc. For patients with advanced cholangiocarcinoma, if surgery is not possible, adequate bile drainage is recommended, and if the patient has deep jaundice, once abdominal pain, high fever or bile duct inflammation occurs, blood pressure drops, shock and even death may occur within 1-3 days. If the pathology of the tumor is obtained after the puncture is obtained, the patient is advised to receive targeted and chemical drugs**, and even drug immunization**, which can improve the patient's quality of life and prolong life.

Hello, the patient was diagnosed with cholangiocarcinoma as a clinical diagnosis, there is no early pathological diagnosis, from the results of B ultrasound, the condition has not yet progressed clearly, but the abdominal MRI or CT should be rechecked regularly, it is recommended that traditional Chinese medicine ** continue, and the constitution allows to consider combining liver intervention**pants transport.

Liu Shuo, Guang'anmen Hospital of Traditional Chinese Medicine.

Suggestion: Analysis: Although there are only two words between cholangiocarcinoma and cholangiocarcinoma, they are actually two terms with different examination methods, with different meanings, cholangiocarcinoma refers to the cancer that occurs in the bile duct during physical examination, but it is not determined which cancer is cancerous.

Cholangiocarcinoma, on the other hand, refers to the pathology of suspicious cancer cells under a microscope to determine that such cancer cells are cholangiopathic. This means that the diagnosis of cholangiocarcinoma is more detailed and the clinician's medication is better known.

Suggestion: Now the blood pressure is high, and the involvement of the cancer is comorbid**. In this case, it cannot be said that any antihypertensive drug will definitely be effective.

The medication for high blood pressure itself does not mean that you can find the best medicine. Blood pressure medication itself works differently for different people, so it is possible that a drug that is used well by one person will not work for another. What I mean is that you should go to a regular hospital to adjust your blood pressure, and don't take it yourself.

Life care: You said to take Chinese medicine now**. I don't know if you are in a Chinese medicine pharmacy prescribed by a regular hospital, it is not recommended that you take Chinese medicine by yourself at the same time as Western medicine**.

Sometimes, the ingredients of Chinese medicine and Western medicine are the same. Take it yourself, there is a risk of overdose. My advice to you is that a regular hospital is regular**.

After all, now the patient has just discovered the cancer, not to say that it is particularly bad, and now the purpose is to remove the original disease and improve the patient's quality of life.

Cholangiocarcinoma is a diagnosis, and cholangiocarcinoma is a pathological result, indicating that the tumor that is cut is transformed from bile duct cells, which is the same thing, but it is called from a different angle.

At present, the best methods for cholangiocarcinoma and cholangiocarcinoma are PD-1 PD-L1

1.Only 70% of patients with liver cancer can be positive for AFP, and I don't know if the other tumor markers you check are normal, such as CA19-9, etc.;

2.Liver hemangioma and cholangiocarcinoma are two completely different diseases, which will not be transformed, and I don't know what hemangioma was diagnosed on 10 years, but it was unlikely to be bile duct cancer at that time, because it was already 3 years;

3' is not very sensitive to chemoradiotherapy, and TACE surgery can be considered 2-3 times;

4.Tumor metastases are most common in intrahepatic metastases, followed by hematogenous metastases, and are more common in the lungs