What are the side effects of mannitol if you take too much

The main effects of mannitol are dehydration and catharsis. Intravenous infusions can dehydrate, reduce intracranial pressure, and avoid cerebral edema. Whereas, the effect of oral administration is a laxative.

Guidance: *** When it is used for dehydration, it is necessary to stop the drug slowly to avoid rebound. Oral mannitol is easy to cause intestinal dehydration, so it is necessary to strengthen rehydration to achieve catharsis and avoid dehydration.

The role of mannitol is mainly used to regulate and control blood pressure. Of course, it is also used for other medical purposes.

Efficacy. Injection:

1) Tissue dehydration medications. It is used for cerebral edema caused by various reasons, reducing intracranial pressure and preventing brain herniation.

2) Lowers intraocular pressure. It can effectively reduce intraocular pressure, and should be used when other intraocular antitenuators are ineffective or in preparation for intraocular surgery.

3) Osmotic diuretics. Used to distinguish between prerenal diuretic factors or oliguria due to acute renal failure. It can also be used to prevent acute tubular necrosis caused by various causes.

Mannitol is a colorless, oily substance that is mainly used for constipation**.

If a large amount of mannitol is given infusion, it can cause mannitol to accumulate in the body, and the blood volume will increase rapidly and in large quantities, leading to heart failure, dilutional hyponatremia, and occasionally hyperkalemia, which can lead to hypovolemia and aggravated oliguria.

In severe cases, it can cause symptoms of the central nervous system, which can cause chills, high fever, thrombophlebitis, and difficulty urinating. If mannitol extravasation can cause tissue edema** necrosis, it can also cause allergic reactions, rashes, urticaria, dyspnea, severe cases can have anaphylactic shock, which can cause dizziness, blurred vision, sunken eyes. In severe cases, it can cause osmotic nephropathy and thirst.

Mannitol is an effective dehydration and cerebral pressure lowering drug, and it does have the best effect on patients with hypertensive intracerebral hemorrhage combined with significant increased cerebral pressure. However, in patients with hypertensive intracerebral hemorrhage, mild elevated cerebral pressure may have a certain preventive effect on early hematoma expansion, and inappropriate reduction of cerebral pressure may lead to decreased pressure hemostasis and induce hematoma expansion. Mannitol can also dehydrate brain tissues other than hematomas, resulting in an increase in the pressure gradient between hematomas and brain tissues, and promoting early hematoma enlargement; In addition, mannitol may leak around the hematoma through ruptured and permeable blood vessels, and further enlarge the hematoma through osmosis.

Therefore, for patients with hypertensive intracerebral hemorrhage, if the cerebral pressure is not prominent, especially within 24 hours of onset, it is not advisable to blindly use dehydrating drugs such as mannitol, so as not to expand the hematoma and aggravate the condition. For severe patients, with significantly increased cerebral pressure, or even signs of cerebral herniation, on the one hand, a large amount of mannitol, furosemide and other drugs need to be used, and on the other hand, the hematoma should be removed as much as possible according to the location, shape and general condition of the hematoma; Even patients with onset of illness for more than 24 hours should be rationally used mannitol and other dehydration drugs on the basis of comprehensive ** according to the intracerebral pressure, and blind, excessive and long-term application should be avoided.

Hello, glad to have a question for you. 1. Efficacy: 1) Mannitol injection can effectively improve blood circulation, promote blood circulation, improve cerebral blood**, and is conducive to the normal operation of the brain and nervous system; 2) Mannitol injection can improve liver function, improve the liver's ability to resist disease, and is conducive to liver disease; 3) Mannitol injection can inhibit the inflammatory response in the body and help to fight infection; 4) mannitol injection can improve myocardial function and inhibit the occurrence of angina; 5) Mannitol injection can also improve the constriction ability of blood vessels, reduce blood pressure, and contribute to the development of high blood pressure.

2. ***:1) Mannitol injection may cause adverse reactions such as dizziness, headache, nausea, vomiting, diarrhea, etc.; 2) mannitol injection may cause an increase in blood sugar, especially for diabetic patients; 3) mannitol injection may cause an increase in serum calcium levels, especially for patients with renal insufficiency; 4) mannitol injection may cause an increase in blood lipid levels, especially for patients with coronary heart disease; 5) Mannitol injection may cause ** reactions, such as emptying rash, itching, erythema, etc. Hope mine is helpful to you.

Drinking mannitol directly is harmful to the human body and cannot be drunk regularly. Oral mannitol must be under the guidance of a doctor, if you take it by yourself, it is easy to have dizziness, collapse, etc. Some special populations, such as hypotension and renal insufficiency, should not use mannitol, otherwise it will be dangerous.

For people with high blood pressure, it is best to drink less mannitol.

Mannitol crystallizes at temperatures below 20. As a result, a large number of crystallizations occur in autumn and winter or when the indoor temperature is very low. Crystallized mannitol must be dissolved before it can be used, so it should be carefully inspected before use to ensure that there are no crystals.

Mannitol is rarely absorbed orally. Intravenous injection is followed by rapid entry into the extracellular fluid without entering the cell. However, when blood mannitol concentrations are high or acidosis is present, mannitol can pass through the blood-brain barrier and cause intracranial pressure rebound.

The diuretic effect appears 1 hour after intravenous injection and is maintained for 3 hours. The reduction of intraocular and intracranial pressure occurs within 15 minutes after intravenous injection, peaks at 30 to 60 minutes, and is maintained for 3 8 hours. This drug can produce glycogen from the liver, but because it is quickly excreted by the kidneys after intravenous injection, the amount metabolized by the liver is generally very small.

The drug T1 2 is 100 minutes and can be extended to 6 hours in the presence of acute renal failure. When renal function is normal, 100g of mannitol is injected intravenously, and 80% is excreted by the kidneys within 3 hours.

I'm not a doctor, I'm a pharmacist, and you can't drink mannitol often.

Mannitol is the drug of choice for cerebral edema. Oral administration can be used for constipation, and can also be used as an aid to examination, but long-term use can cause intestinal fistula, intestinal obstruction and other diseases.

No!

Mannitol is a dehydrating agent extracted from brown algae cells, which is medically used for tissue dehydration. Diuretic effect. Long-term use can disrupt the circulation of somatic cells and cause electrolyte chaos.

Uses: Mannitol is a good diuretic in medicine, reducing intracranial pressure, intraocular pressure and kidney medicine, dehydration drugs, sugar substitutes, also used as an excipient for tablets and a solid and liquid diluent. As a hyperosmolar antihypertensive drug, mannitol injection is a commonly used drug in clinical rescue, especially in the rescue of brain diseases, and has the characteristics of rapid antihypertensive effect and accurate efficacy required by drugs to reduce intracranial pressure.

After mannitol enters the body, it can increase plasma osmolality, dehydrate tissues, reduce intracranial pressure and intraocular pressure, and after filtration from the glomeruli, it is not easy to be reabsorbed by the renal glomeruli, so that the urine osmotic pressure increases, and a large amount of water is brought out and dehydrated, which is used for cerebral trauma, edema caused by lack of oxygen to brain tissue, edema caused by extensive burns, and ascites glaucoma caused by renal failure. It can also prevent and treat early acute renal insufficiency.

1. Water and electrolyte imbalances are the most common. Somo Tsuki.

Rapid intravenous mannitol can cause the accumulation of mannitol in the body, a rapid and large increase in blood volume (especially in acute and chronic renal failure), leading to heart failure (especially when there is cardiac impairment), dilutive hyponatremia, and occasionally hyperkalemia;

Inappropriate excessive diuresis leads to hypovolemia and worsens oliguria;

Transfer of large amounts of intracellular fluid to the outside of the cell can lead to tissue dehydration and can cause central nervous system symptoms.