How to conduct animal experiments, and whether animals should be used for experiments

Uh, what kind of animal experiments do you do?

Laboratory animals are the foundation and important supporting conditions for life science research.

At present, almost all scientific research, teaching, production, verification, safety evaluation and achievement evaluation in the field of life sciences are inseparable from laboratory animals, which are called living instruments and have an irreplaceable role.

Driven by modern science, laboratory zoology has developed into a comprehensive emerging discipline, and its development and application degree is regarded as an important indicator to measure the development level of a country, a region, a sector or industry, especially biomedicine.

Looking back at the history of biomedical development, it is not difficult to find that many landmark or epoch-making research results are often closely related to laboratory animals and animal experiments.

The physiologist Pavlov once pointed out that "it is indisputable that people cannot understand the laws of the organic world without experiments and observations on living animals", "the whole of medicine, only through the flame of experiments, can become what it ought to be", and "only through experiments can medicine achieve the final victory".

These arguments have been and are being confirmed by the course of medical development.

According to international statistics, more than 60% of the world's biomedical research is carried out using laboratory animals, and about half of the Nobel Prize in medicine projects are inseparable from laboratory animals.

The vast majority of experimental sciences such as physiology, pathophysiology, pharmacology, etc., are done using laboratory animals.

It can be seen that it is difficult to envision the development of biomedicine without laboratory animals and animal experiments.

It can be seen that the development of modern biomedicine and modern biomedicine has always been inseparable from laboratory animals.

This is a controversial issue, and different people have different views. On the one hand, animal experiments are one of the important means of scientific research, which can help scientists understand the knowledge of biology, medicine and pharmacology, as well as develop new methods and drugs. On the other hand, some people believe that animal experiments are unethical because animals also have the right to be free from abuse and suffering, and the results of animal experiments are not always applicable to humans, as humans and animals are very different in terms of physiology and biochemistry.

At present, many countries and regions have laws and ethical regulations that restrict or prohibit the use of paddles in animal experiments. If animal testing is required, relevant laws and regulations must be complied with to ensure that the welfare and rights of the animal are protected, and the experiment should only be carried out if there are no other alternatives.

Overall, animal experimentation is a complex issue that requires trade-offs and considerations across multiple aspects such as science, ethics, and law. <>

The experimental process of the animal experiment is as follows:

As we all know, before animal experiments, the first thing is to purchase and transport experimental animals, so after the experimental animals are prepared in place, what processes do they have to go through before they can officially enter the experimental link?

The first step is to enter the site for quarantine. Confirm the animal strain, male and female, quantity, and observe the mental state of the animal, whether there is any disease of the animal, and whether the animal is qualified.

The second step is feeding observation. During this period, it is only necessary to separate the cages according to the males and females, and the appropriate number of cages can be raised. The observation period for rodent feeding is generally 3-7 days, and for large animals, it is generally 2-3 weeks.

The third step is the animal labeling. Animal marking methods should follow the principles of clear labeling, durability, simplicity and application, and commonly used animal return macro marking methods include dyeing, ear margin cutting, branding, license plate and other methods.

Fourth, randomization. Follow the principle of random allocation, avoid the interference of human subjective factors, minimize the influence of various differences on the experimental results, and reduce the occurrence of experimental errors.

The fifth high-world step, experimental treatment. Enter the experimental link, including modeling, drug administration, surgical treatment, etc.

In the above links, randomization is an important embodiment of the randomization principle of experimental design, and it is also the main factor affecting the experimental results. The randomization of experimental animals can be divided into random selection of animals from the population and random grouping of all animals. The former is referred to as random sampling, and the latter is referred to as random grouping.

Experimental animals include animals that have been domesticated for a long time and are bred according to scientific requirements, such as: mice, rats, miniature pigs, rabbits and ground modified rats. Laboratory animals are animals that are bred in captivity and are used for scientific research, teaching, production, identification and scientific core experiments.

Experimental animals are laboratory animals in a broad sense, including experimental animals, including economic animals, wild animals, ornamental animals, etc.

Laboratory animals are animals specially bred for experimental use, mainly referring to animals that are bred and bred as scientific research in the fields of medicine, slag pharmacy, biology, and veterinary medicine.

Experimental animals may include living and dead domestic animals, poultry and wild animals, and economic animals refer to animals that are cultivated, bred and produced as needs of human social life.