Common drugs of anticancer drugs, classification of antineoplastic drugs

Eat sea cucumber polypeptides.

There is an ingredient in sea cucumber polypeptide called sea cucumber saponin, which has a good adjuvant effect on the postoperative and postoperative radiotherapy and chemotherapy of the tumor. Sea cucumber saponins are found in high amounts in tissues such as the body wall, internal organs, and glands of sea cucumbers. Ginseng saponin is an antitoxic agent that inhibits the growth of certain cancer cells and has a strong anti-fungal effect.

The selenium contained in sea cucumber can inhibit the growth of cancer cells and blood vessels, and has a well-known anti-cancer effect. Sea cucumber has obvious anti-cancer curative effect, and has a significant inhibitory effect on the growth and metastasis of malignant tumors.

Panax notoginseng can fight cancer.

Modern research has proved that ginsenoside RD in the ingredients of Panax notoginseng can enhance immune function and inhibit the growth of carcinomatocytes. And the ginsenoside rh2 in it promotes the transformation of cancer cells into non-cancer cells. Therefore, Panax notoginseng is effective against cancer.

The anti-cancer effect of Panax notoginseng has long been applied in clinical practice, and in Japan, Panax notoginseng is regarded as an anti-cancer holy product called "Panax notoginseng". The reason why Panax notoginseng has anti-cancer effect is directly due to its excellent hematopoietic function.

Panax notoginseng saponin RD can inhibit 92% of cultured tumor cells, and RD also has a significant inhibitory effect on cultured tumor cells. Saponin RHL inhibits the growth of melanoma (B16) in mice, allowing cancer cell redifferentiation to induce reversal into non-cancer cells. In addition, the polysaccharides in Panax notoginseng can significantly inhibit sarcoma-180 in mice in vivo.

Panax notoginseng saponins can improve the phagocytic function and humoral immunity function of mouse macrophages. The main components in Panax notoginseng that have an effect on immune function are Panax notoginseng saponins and Panax notoginseng polysaccharides. In addition, Panax notoginseng water infusion can shorten the coagulation time of rabbits, and increase the number of platelets and is known to have hemostatic effect; It has obvious preventive and ** effects on experimental arthritis tract in rats.

It is worth choosing and noting: 1. Look at the content of active ingredients and whether there are bad additives; 2. Look at the platform, whether the qualifications are complete, whether there is a traceability mechanism, and the after-sales service is guaranteed.

It is simply divided into chemotherapy drugs and biologics.

Chemotherapy drugs: dihydrofolate reductase inhibitors: methotrexate (MTX) Thymidylate synthase inhibitors: fluorouracil (5-fu) Purine nucleotide interchange inhibitors: mercaptopurines (6-MP) Nucleotide reductase inhibitors: hydroxyurea (HU).

DNA polymerase inhibitors: cytarabine (ARA-C) biologics type classification:

Cytokines: interferon, interleukin, tumor cell necrosis factor, and hematopoietic growth factor monoclonal antibodies.

Cell differentiator: retinoid

Immune cells: tumor-infiltrating lymphocytes and lymphocyte-activated killer cells ANon-specific: BCG, levamisole.

b.Specificity: Tumor vaccine (for adjuvant malignancy**) gene**.

Antineoplastic drugs ---

1. Drugs that inhibit nucleic acid (DNA and RNA) biosynthesis: such as fluorouracil, cytarabine, hydroxyurea, methotrexate, 6-mercaptopurine, etc.

2. Drugs that directly destroy the structure and function of DNA: such as alkylating agents, platinum preparations and anti-tumor antibiotics;

3. Drugs that interfere with the transcription process and prevent RNA synthesis: such as actinomycin D, daunorubicin, doxorubicin, etc.;

4. Drugs that affect protein synthesis and function: such as vinblastine and paclitaxel;

5. Drugs that affect hormone balance: such as estrogen, androgen, anti-estrogen, adrenocorticosteroid, etc.;

6. Anti-tumor adjuvant drugs: such as ondansetron, calcium leucovorinate, etc.

Commonly used antineoplastic drugs are:

fluorouracil: branch;

mitomycin: 2 mg vial;

doxorubicin: 10 mg vial;

epirubicin: 10 mg vial;

cisplatin: 10 mg vial;

Kangai Injection: 10ml vials;

All personal work summaries, I hope it will be useful to you.

The selenium and quercetin in Wangyin mushroom have the effect of anti-cancer, anti-cancer and anti-tumor, Wangyin mushroom can inhibit the proliferation of Xiang tissue, prevent cancer cells from metastasizing, and induce apoptosis of cancer cells.

It is roughly divided into 5 categories, if you don't understand, ask me again.

At present, there is a high incidence of malignant tumors in the world, and surgery and chemotherapy have positive efficacy, but at the same time, they also have a large effect. The anti-cancer Chinese patent medicine has unique advantages in clinical application, such as focusing on regulating the whole, attacking and supplementing at the same time, and enhancing the efficacy.

The following introduces several common proprietary Chinese medicines with anti-cancer effects for the reference of the majority of patients.

1.Toad crisp preparation.

Functional detoxification, swelling, pain relief, used for liver cancer, pancreatic cancer, etc.

2.Curcuma preparations.

The main ingredient is volatile oil, which has a definite curative effect on cervical cancer.

3.Aconitum injection.

Improve tumor symptoms and significantly reduce cancer pain.

4.Rokamimaru.

It can be anti-inflammatory and sterilized, reduce swelling and muscle, detoxify and relieve pain, and has obvious effects on gastric cancer and esophageal cancer.

5.Angong Niuhuang Pills.

Function: Clearing heat and detoxifying, sedation, ** in the middle and advanced stages of liver cancer, can control fever, gastrointestinal bleeding, liver pain and jaundice and other symptoms.

6.Plum blossom dot tongue pill.

The function is to clear heat and detoxify, invigorate blood and dispel blood stasis, and the effective rate for ** leukemia is 81%, and the blood picture generally improves in seven to ten days, and then the symptoms improve.

7.Xihuang pills.

Function: Clearing heat and detoxifying, dissolving phlegm and dispersing knots, invigorating blood and removing stasis. It is used for various tumors such as breast cancer, lung cancer, and intestinal cancer. Modern pharmacological experiments have proved that this drug can effectively inhibit the growth of prismatic cell tumors and sarcomas in mice.

8.Ginseng preparations.

It has a protective effect on the white blood cells of tumor patients, and can prevent and treat primary liver cancer caused by radiotherapy and chemotherapy.

9.Scattered spirits.

The function is soft, hard and dispersing, soothing the liver and regulating qi, and is used for breast cancer.

10.Lily solid gold pills.

Function: Nourish yin, moisten the lungs and relieve cough, used for ** lung cancer.

11.Lotus leaf pills.

Function: cool blood and stop bleeding, used for all kinds of cancerous bleeding.

Hello, cancer can be said to be now people will feel panic when they hear it, as if to indicate the arrival of death, with the development of science and technology, a large number of medical people have invested in the search for the first cancer (stomach cancer insists on sunshine Tang Junhua).

Since the first generation of platinum drugs cisplatin has been used in clinical practice, platinum drugs have developed in two broad directions, one is to improve the toxicity of cisplatin; The second is to overcome its drug resistance in the tumor. Since the 70s, only about 10 of the thousands of platinum compounds have been screened for clinical trials. By 1986, carboplatin was launched as the second-generation platinum drug, and cisplatin and carboplatin are now accepted worldwide.

With the in-depth study of the mechanism of action, structure-activity relationship, and clinical in-depth research on platinum drugs in recent years, it has been found that a class of platinum complexes with diaminocyclohexane as a platinum-loaded ligand not only improves the toxicity of cisplatin and carboplatin, but also expands their activity spectrum, and is active against many cisplatin- or carboplatin-resistant cell lines or tumor strains. This new type of platinum drug is known as the third generation of anti-cancer drugs, and its representative drugs include loplatin, oxaliplatin, etc.

This is part of the review I wrote, and my graduation project was about platinum-based cancer drugs, hopefully.