Specific Processes of Lipid Metabolism 5, Specific Processes of Lipid Metabolism

The biochemical process of fat metabolism in the body after absorption is mainly divided into: the metabolism of four types of lipids: triglycerides, phospholipids, cholesterol, and plasma lipoproteins, which are affected by insulin.

Complex and precise regulation of glucagon, dietary nutrition, and biochemical enzyme activity in the body are transformed into substances and components required for various delicate biochemical reactions in the body. The liver, adipose tissue, and small intestine are important places for the synthesis of fat, and the liver has the strongest synthesis ability. After synthesis, it should be combined with apolipoprotein, cholesterol, etc. to form very low-density lipoprotein (VLDL), which can be transported into the bloodstream and transported to extrahepatic tissues for storage or utilization.

If the triglycerides synthesized by the liver cannot be transported in time, fatty liver will form.

When long-term starvation and sugar ** are insufficient, fatty acids are used in large quantities to generate acetylcoa for oxidation and energy, and a large number of ketone bodies are produced. The liver is the organ that produces ketone bodies, but it cannot use ketone bodies. Brain tissue cannot utilize fatty acids, while ketone bodies are soluble in water and have small molecules that can pass through the blood-brain barrier.

Severe diabetes.

Patients, glucose.

If it is not effectively utilized, fatty acids are converted into a large number of ketone bodies, which exceed the ability of extrahepatic tissues to utilize, causing an increase in ketone bodies in the blood, which can lead to ketoacidosis.

1 Pinyin 2 Annotations.

zhī fáng de dài xiè

Fat metabolism refers to the decomposition of fat in food into glycerol and fatty acids in the digestive tract through bile emulsification and lipase catalysis, which are absorbed by the villous epithelial cells of the small intestine in the form of diffusion, and then synthesize fat in the epithelial cells, and then combine with lipoproteins and lipids and cholesterol to enter the capillary lymphatic vessels, enter the blood circulation through the lymphatic circulation, and finally be transported to various parts of the tissues. The metabolic fate of lipids after entering the human organism: first, the tissues involved in the composition of the animal body, such as phospholipids are the components of biological membranes; second, it is stored as a spare substance in subcutaneous, mesentery, omentum, etc.; Third, if necessary, glycerol, fatty acids, etc., can be decomposed, and then directly decomposed into CO2 and H2O, or converted into liver glycogen, etc.; Fourth, it is used by various glands to generate their own special secretion bands, such as sebum secreted by sebaceous glands, milk produced by mammary glands, and various dust wheel steroid hormones secreted by endocrine glands.

It is to go through an obstacle, and the obstacle is the mitochondrial membrane, and the mitochondria can be burned'Burn the fat to make it release'Put energy, fat in'into mitochondrial combustion'Schematic diagram of burning.

Body'The body consumes, but the long-chain fatty acids can't get through this obstacle, so carnitine plays the role of a porter in it! I carry long-chain fatty acids to the screen little by little'Shelter the outside and send it to the mitochondria to further oxidize!