What are the symptoms of progressive muscular dystrophy?

1. Symmetrical weakness and atrophy of limb muscles, walking slowly and falling is not easy to get up, it is difficult to go up and down stairs, and the heel cannot touch the ground. Walks in a typical duck stride.

2. The calf muscles are cold, hard and thick. Major**: Dominant or recessive inheritance or gene mutation sex and age of predisposition:

It is more common under 10 years old, and it is more common in men than womenThe main symptoms: more proximal muscle atrophy, distal pseudohypertrophy weakness, duck gait, protrusion, toe walking, winged shoulder. Positive main pathological changes in Gowers's disease:

Degeneration of muscle cells, necrosis, hyperplasia of fat cells and connective tissue, loss or abnormality of intramuscular dysplasms.

You can use the Healing Recipe Drink**.

Limb-girdle muscular dystrophy: seen in both sexes, it begins in children or young adults, first affects the pelvic girdle muscles and psoas major muscles, difficulty walking, inability to climb stairs, swaying gait, often falls, and some only affect the quadriceps muscles. The course of the disease progresses very slowly.

Suggestions: Facial-shoulder-humeral muscular dystrophy: both men and women, onset in youth, first facial muscle weakness, often asymmetrical, unable to show teeth, protruding lips.

With the eyes closed and frowning, the orbicularis oculi muscle may have pseudohypertrophy, resulting in hypertrophy of the lips and protruding lips, and some shoulder and humeral muscles are affected first, so that the arms cannot be raised to form a hanging shoulder, and the muscles of the upper arm are atrophied, but the muscles of the forearm and hand are not violated. The course of the disease progresses very slowly, often with abruptness or remission.

The clinical manifestations of the various types of progressive muscular dystrophy are as follows:

1.Pseudohypertrophic muscular dystrophy.

Children develop their movements later than normal children, such as learning to walk late, having a staggering gait, not being able to run, and often falling for no reason. At the age of 3 to 5 years, the symptoms gradually become obvious, due to the weak muscles of the pelvic girdle, unable to jump and run, stairs laborious, abnormal walking posture, excessive protrusion of the lumbar spine, and the pelvis swinging to both sides, showing a typical "duck step". Due to weakness of the rectus abdominis and iliopsoas muscles, when the patient rises from the supine position, first turns over to the prone position, then straightens the arms to support the bed with both hands, and the legs are also straightened, and gradually supports the knees with both hands, and climbs the thighs up in turn until they stand up.

Atrophic and weak muscles begin mainly in the thigh and pelvic girdle muscles, and gradually progress to the calf muscles, proximal upper limb muscles, distal upper limb muscles, and finally respiratory muscle paralysis. Gastrocnemius hypertrophy is often very significant, and other muscles such as tongue, deltoid, and gluteal muscles may be hypertrophied. DMD is often associated with myocardial damage, involving the ventricles, atria, and conduction system.

In the late stage, heart enlargement and heart failure occur, and about 10% of patients can die due to cardiac insufficiency. In addition, joint contractures, foot drop, scoliosis and other symptoms may occur. Most of them are unable to walk at the age of 12, and they die of respiratory muscle failure due to respiratory muscle weakness and respiratory tract infection around the age of 20.

The clinical manifestations of BMD are similar to those of DMD, but the age of onset is later, about 5 to 15 years old, the disease is milder, the rate of progression is slower, and it can still walk after the age of 12, and the survival time is longer, and some can be close to the normal lifespan.

2.Limb-girdle muscular dystrophy.

The autosomal recessive form is more common, has an earlier onset, has more severe symptoms, and begins in childhood, adolescence, or adulthood, and is manifested by muscle atrophy and weakness of the pelvic girdle muscles and shoulder girdle muscles, resulting in difficulty in going upstairs, difficulty in squatting, difficulty lifting both upper limbs, pterygoid scapula, and facial muscles are generally not affected. Gastrocnemius hypertrophy may be present. Some patients have cardiac involvement.

3.Facicoscapulohumeral muscular dystrophy.

Weak facial muscles are the first symptom, but they are often ignored because of the insidious onset of the disease, which is mild and mild. It is manifested as weakness or whiteness of the closed eyes, shallow nasolabial folds during tooth presentation, inability to whistle and bulge cheeks, thickened and outward curled lips, and a typical myopathic appearance. The shoulder girdle muscles are weak, and the winged shoulder blades appear.

The pectoralis major muscle is weak and the chest is awkward. Muscles of the proximal upper extremity, proximal lower extremity, and distal extremity can be affected. Hypertrophy of muscles such as deltoid muscles can be seen.

Some cases are complicated with exudative retinitis and neuropathic hearing loss.

Progressive muscular dystrophy is a neurological disease that can occur in people of any age, and once the skeletal muscle develops progressive weakness or atrophy, it can affect the health of the central nervous system or the heart after aggravation. Considering the seriousness of progressive muscular dystrophy and its obvious symptoms, it is necessary to have an in-depth understanding of this in life. So what are the symptoms of progressive muscular dystrophy?

1. Duchenne muscular dystrophy.

Duchenne muscular dystrophy is pseudohypertrophic muscular dystrophy that begins at the age of 3 to 5 years and can insidious the weakness of the pelvic girdle muscles, followed by slow walking, tiptoe landing and easy falling. As the disease progresses, it will develop varying degrees of intellectual disability, followed by uncomfortable symptoms such as vomiting, abdominal pain and diarrhoea.

2. Becker-type muscular dystrophy.

Becker muscular dystrophy causes symptoms that begin with the pelvic girdle or proximal lower extremity muscles, and gradually spread to the scapulosplenic girdle, resulting in pseudohypertrophy of the gastrocnemius muscle.

3. Facicoscapulohumeral muscular dystrophy.

Facicoscapulohumeral muscular dystrophy can lead to healthy involvement of the facial and scapular girdle muscles, with fewer facial expressions during the onset and weakness of eyelid closure and sometimes sclera when symptoms worsen, especially when whistling or puffing out the cheeks. If it is not effective**, it will gradually develop to the shoulder-splenic girdle, deltoid muscle, and biceps brachii.

4. Limb-girdle muscular dystrophy.

Limb girdle muscular dystrophy usually begins at the age of 10 to 20 years, and the pelvic girdle muscles atrophy to varying degrees in the early stage, and once aggravated, it will produce discomfort such as lumbar lordosis or duck walking.

Pseudohypertrophy, faciculo-scapular-humeral muscular dystrophy, limb-girdle muscular dystrophy,

In progressive muscular dystrophy, the main symptoms are tearlessness of the muscles, long, weak lips, inability to puff up the esophagus, and difficulty climbing steps.

In progressive muscular dystrophy, the predominant symptom is symmetrical muscle weakness and atrophy that progressively worsens. There are actually many types of this disease, the most common being pseudohypertrophy. Pseudohypertrophy is in the gastrocnemius muscle of the lower leg, there will be muscle hypertrophy, weakness of the pelvic girdle muscle, and a feeling of difficulty standing up, which is manifested as slow walking, tiptoe landing, and easy falling.

The shoulder girdle of the upper extremities and the muscles of the upper arm are also affected, but to a lesser extent than the pelvic girdle muscles. There is also facioscapulohumeral muscular dystrophy, in which the muscles of the face and shoulder girdle are most susceptible, and there will be weakness in eyelid closure and difficulty whistling and cheek puffing. The shoulder girdle muscles are the deltoid, biceps, and triceps, and these muscles also experience significant atrophy and weakness.

Limb-girdle muscular dystrophy is mainly muscle atrophy and weakness in the pelvic girdle and shoulder girdle muscles. Oculopharyngeal muscular dystrophy is mainly manifested by ptosis of the upper eyelid, eye movement disorders, dysphagia, and slurred speech.

Progressive muscular dystrophy is not only frequent, but also extremely harmful, especially many reasons induce the emergence of the disease, resulting in serious damage to the patient's motor system, and easy to affect the health of vision and central nervous system, friends should correctly understand the disease, beware of their own physical changes, especially the symptoms of mastery, the following for you to reveal the symptoms of progressive muscular dystrophy.

1. Limb girdle muscular dystrophy, the proximal end of the limbs of the patient in the early stage is severely weak, and gradually involves the distal end of the limbs, and the ankle joint is obviously contracture in the later stage of the disease, and the disease progresses slowly, and finally loses the ability to walk.

2. Myotonic dystrophy, multiple systems of patients are damaged, in addition to the symptoms of muscle atrophy, muscle weakness and muscle rigidity, there are also some endocrine system damage and heart damage, resulting in the patient's neuropsychiatric and eye health are affected.

3. Distal muscular dystrophy, the weakness of the distal muscles of the limbs is more obvious, with the weakness and atrophy of the extensor muscles being the most obvious, and the patient has no sensory impairment or autonomic nerve damage.

4. Facicoscapulohumeral muscular dystrophy, the age of onset of this type of patients varies greatly, generally between 5 and 20 years old. Lesions tend to invade the muscles of the face, shoulder girdle, and upper arms. When the patient's facial muscles are affected, the patient's facial expression is indifferent, and it is easy to produce symptoms such as closing eyes and weak tooth display, resulting in the patient's arms unable to rise.

Hello. Progressive muscular dystrophy is a disease of primary skeletal muscle caused by hereditary factors, and the main clinical manifestations are slow, progressive muscle atrophy, and muscle weakness, which gradually lead to varying degrees of movement disorders. The most common clinical symptoms are muscle atrophy, muscle weakness, and dyskinesia as the disease progresses.

At the beginning of the disease, it may only be manifested as the muscles of the thighs are found to be gradually taper, and then as the disease progresses, the muscles in other parts will gradually atrophy and thin, and the muscle volume will become smaller, and then as the degree of muscle atrophy increases, the degree of muscle weakness will also gradually increase. With the aggravation of muscle atrophy and muscle weakness, it will slowly lead to the patient's weakness in walking, and when changing from a squatting position to a standing position, it will be manifested as the need to support the wall, and even gradually unable to stand up independently. Once similar clinical manifestations are found, they should go to the neurology department for comprehensive diagnosis and treatment as soon as possible, and carry out necessary electromyography examinations, electrophysiological examinations, etc., so as to carry out reasonable ** as soon as possible.

Progressive muscular dystrophy is a neurological disease, which is a disease with a genetic predisposition, generally with an obvious family history, and patients are generally young, and the corresponding clinical manifestations will appear.

In general, the early symptoms of progressive muscular dystrophy mainly include: first, patients may have some mild fatigue throughout the body, heavy physical activity is not tolerated, some students' sports performance is not particularly good, and climbing stairs will be affected accordingly.

Second, there will also be some muscle atrophy, which is relatively mild, which is mainly an early symptom. As the disease progresses, the patient's muscle weakness becomes more and more severe, and the muscle atrophy becomes more and more severe, and even daily activities are significantly affected.

In addition, there may be some associated clinical manifestations such as muscle pain.

Muscular dystrophy is a common chronic disease, mostly occurs around children, and the incidence rate of men is higher than that of women, most children will have clumsy movements, delayed walking, shaky steps and other symptoms, which has attracted the attention of parents and friends, the emergence of the disease hinders the growth of children, brings serious harm, for which muscular dystrophy needs to appear as soon as possible.