What causes demyelination?

Demyelination**We commonly have inherited congenital myelination disorders, such as adrenoleukodystrophy. In addition, if the patient has ischemia and hypoxia, it is common to have cerebral infarction or cardiorespiratory arrest after resuscitation, which will lead to the occurrence of demyelinating emergency. In addition, there are nutritional deficiencies, such as long-term alcoholism, which can also lead to demyelinating of the nerves.

In addition, there are patients with a bad stomach, that is, atrophic gastritis, these diseases will lead to vitamin absorption disorders, and some are autoimmune disorders, such as Behcet's disease, lupus, these patients are also prone to demyelination. There are also various poisonings that can also lead to demyelination, and our common poisoning is carbon monoxide poisoning and mercury poisoning.

In order to clarify the cause of demyelinating lesions, we must first have an understanding of myelin, if the myelinated nerve fibers such as wires, the outer packaging of the wires is equivalent to the myelin sheath, and the wires inside are equivalent to the axons of the myelinated nerve fibers, and some other reason causes the myelin sheath to fall off, which is called demyelinating lesions. The cause may vary depending on the disease, such as acute.

Hello, please consult the situation, consider spinal cord dehydration sheath, we also call Guillain-Barré syndrome, it causes sensory and motor dysfunction, the need to take hormones as well as improve immunity, immunoglobulin, slowly start to stop the drug. Be patient.

Demyelinating lesions are diverse, and current research suggests that they are mainly related to genetic factors or genetic mutations. It is relatively more common in Europeans and lower in Africans, and some patients are due to infectious factors, such as encephalitis or measles virus infection. It is also partly due to the presence of insufficient oxygen supply to the brain or cerebral arteriosclerosis.

At present, there is no particularly effective ** measure, if there is a bacterial inflammatory infection, it is mainly necessary to use anti-infective drugs to suppress the infection and avoid the use of drugs that cause demyelination. If the disease progresses, nutritional neurological drugs can be used to improve symptoms, and good sleep habits need to be practiced.

1.Genetic factors associated with congenital myelin disorders, such as inadequate adrenal white matter nutrition.

2.Ischemia or hypoxia, such as demyelinating encephalopathy that occurs after the heart has stopped breathing.

3.Nutrient deficiencies, such as lack of oxygen and vitamin B12 deficiency.

4.In autoimmune diseases, autoantibodies attack their own myelin sheath. Such as: Behcet's disease, lupus brain, etc.

5.Body poisoning, CO poisoning, and mercury poisoning can all cause such conditions.

From the perspective of traditional Chinese medicine, the main factor of demyelinating disease is the blockage of qi and blood, because the flow of qi and blood is not smooth, and the patient's limbs cannot be supported. The symptoms of the patient are: lack of qi and blood, cold and dampness, qi stagnation and blood stasis, joint strain and hyperplasia, the circulation of qi and blood in the whole body or local of the patient will be affected, and the patient will have numbness and pain in the limbs.

The body is weak, or overworked, and it is easy to have both qi and blood deficiency. If the blood is deficient, the blood qi will be weak. Or because of the evil of wind and cold, the body is affected by cold, wind, and dampness, resulting in numbness.

The three highs alleviate overeating and eating too much greasy food, which leads to blood viscosity and poor blood circulation, resulting in numbness.

Demyelinating patients need to exercise more, should prepare a relatively large mirror, need to correct their bad posture at any time, and can also use acupuncture massage. If conditions permit, you can let the ** teacher guide you to train and practice sitting. To help maintain good posture, you can also practice standing and squatting.

The time needs to be decided according to your own tolerance, not less than 30 minutes, so that you can have a good effect.

Demyelination occurs when the myelin sheath of the axons of the cerebrospinal cord is lost. There are two categories: myelin destruction; Disorders of myelination. Spinal inflammatory demyelinating diseases are currently considered to be immune-mediated diseases, and their clinical features are:

The patients were children and young adults;

Acute onset, common history of cold, fever, infection, rash, vaccination, cold, childbirth or surgery 1 month before the illness;

A thorough neurological examination often reveals evidence of other central nervous system involvement in addition to spinal cord symptoms and signs;

cerebrospinal fluid examination is positive for oligoclonal bands;

Electrophysiology and MRI can detect some subclinical lesions in the brain; MRI reveals abnormal signals of white matter in the brain. Some myelittic demyelinating lesions present:"Pseudoneoplasia"Manifestations, the MRI shows a mild mass effect, mild edema around it, and there may be patchy hemorrhagic signals, which can easily be misdiagnosed as spinal cord tumors. At present, the effect of internal medicine drugs** is not good.

Therefore, neurosurgical intervention is inevitable and necessary.

Demyelinating myelitis is usually acute multiple sclerosis (MS) spinal type, and the clinical presentation is similar to that of postinfectious myelitis, but the progression is slow, and the disease usually peaks within 1 to 3 weeks. The prodromal infection may be subtle, usually incomplete transverse lesions, with weakness or paralysis of one or both lower extremities, with numbness, the level of sensory impairment is inconspicuous or two-plane, and urinary and fecal disorders are present. Evoked potentials and MRI may reveal lesions elsewhere in the CNS.

The demyelination of nerves in the human brain is demyelination, and demyelinating diseases are acquired diseases with different clinical manifestations but similar characteristics. It is characterized by the loss of myelin in nerve fibers, while nerve cells remain relatively intact. The role of the myelin sheath is to protect neurons and allow nerve impulses to be transmitted quickly on neurons.

Therefore, the loss of myelin impulse transmission is affected. In acute demyelinating diseases, the neuromyelin sheath can be regenerated and generally has little effect on function. Chronic demyelinating neuropathy is characterized by incomplete functional recovery due to repeated demyelination, thickening of nerves, and axonal loss.

**There may be many aspects involved, including genes (genetic predisposition), environmental factors (food, climate, geography, and pathogenic infection), and the patient's own immunity.

Predisposing factors. Infection, overwork, trauma, agitation, inadequate vitamin D intake, and discontinuation of disease-modifying drugs in remission can all contribute to the disease or promote the disease** or exacerbation.

Clause. First, it is caused by cerebral ischemia and hypoxia, especially the lesions of small arterioles, causing demyelinating lesions in subcortical white matter.

Clause. 2. Pay attention to autoimmune inflammatory reactions, such as multiple sclerosis, neuromyelitis optica, etc.