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Severe symptoms of muscle weakness manifest as neuromuscular conduction disorders involving generalized skeletal muscles. Weakness is manifested as fatigue, exertion and rest, and skeletal muscle weakness is generally severe in the morning and evening. Depending on the muscle group affected, there may be different presentations.
Lesions involving the levator palpebrae muscle may cause drooping eyelids, and the eyelids become smaller and smaller when the eyes are opened to see things, and finally they may not be able to open at all. After closing the eyes and resting, they can be opened again, and the eyelids can be lifted to look up and down, left and right, and double vision and eye movement disorders may occur, which is a condition that affects the extraocular muscles. Facial expression muscles are affected, and weakness of eyelid closure may occur, and slowness may occur when grinning teeth.
The patient has a wry smile due to impaired levator labial activity, and the corners of the mouth droop down when he smiles. If the swallowing and masticatory muscles are affected, eating and eating may be difficult.
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Patients with muscle weakness will have a decrease in muscle strength at the lesion site, such as unstable standing in the legs, or even unable to stand, and in severe cases, there will be limited flexion and stretching of the lower limbs, trembling when holding things in the upper limbs, or unable to pick them up, and the lifting and extension of the upper limbs will be significantly restricted, and some will also affect other muscle tissues to produce corresponding symptoms. For patients with muscle weakness, they should be examined in time to determine the causes of muscle weakness, especially to pay attention to stroke, progressive muscle atrophy, myositis, etc., as well as sports injuries and other reasons, which should be noteworthy.
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Symptoms of muscle weakness, especially early symptoms, are often subtle or more likely to go unnoticed. Muscle weakness is a chronic condition. Many patients get tired easily, and rest can relieve the condition. The early symptoms of muscle weakness are subtle and tend to be overlooked.
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Muscle weakness is characterized by the inability of muscles to produce normal force, resulting in a loss of strength in some muscle groups.
The patient's subjective feeling is fatigue and fatigue. As the disease worsens, the patient may feel that the limbs are sore, or even a muscle or muscle group, or the entire limb is paralyzed, and the patient may find it difficult to complete the demands of daily life or work occupation.
The level of muscle weakness can be determined by different neurological examinations.
The muscle strength test is mainly divided into six grades: when the limb is completely paralyzed, it is grade 0; If only muscle contractions can be seen, it is grade 1; Being able to move on a flat surface is level 2; Being able to defy gravity is level 3; Ability to defy gravity and partial resistance is level 4; Being able to fully defy gravity and drag is normal level 5. This is the manifestation and grading of muscle weakness.
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Ptosis: This is caused by paralysis of one or both extraocular muscles and may be accompanied by strabismus.
In double vision, in severe cases, eye movement is significantly limited, or even the eyeball is fixed, but the pupillary sphincter is not affected, that is, the pupillary accommodation function is normal;
Dysphagia and chewing: This is caused by the involvement of the facial and throat muscles, and at the same time, there will be an indifferent expression, a wry smile, continuous chewing weakness, choking on water, and more laborious swallowing of chewed food when eating;
Hoarseness: This is also caused by the involvement of the facial and throat muscles, which can be accompanied by nasal speech, dysphonia, and unclear pronunciation when speaking;
Difficulty raising head: when the sternocleidomastoid muscle and trapezius muscle are involved, it manifests as neck weakness, difficulty in raising the head, weakness in turning the head and shrugging the shoulders;
Weakness of the arms and legs: The muscles of the limbs are affected by proximal weakness, which is manifested as difficulty in raising the arms, combing the hair, and climbing stairs, but the tendon reflexes are usually unaffected and the sensation is normal;
Dyspnea: Respiratory muscle involvement often leads to adverse consequences, and medical attention should be sought as soon as possible if you experience difficulty breathing;
Morning and evening severity: this is a characteristic of the symptoms of the disease, i.e., daily fluctuations, muscle weakness that worsens after exertion in the afternoon or evening and lessens after morning or rest.
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1.ptosis: manifested by monocular ptosis or alternating ptosis; 2.
Ocular motility disorders: patients have unclear vision and diplopia; 3.proximal limb weakness, weakness in chewing, choking on water, difficulty swallowing; 4.
Respiratory muscle weakness: the patient has difficulty breathing.
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1. Weakness of limbs.
The most typical symptom of muscle weakness is weakness of the limbs and trunk, and it is often more severe in the lower extremities, and the lower extremities often have decreased or absent reflexes. In general, the muscle contraction after a short period of exertion leads to an increase in muscle strength, but the muscle strength will be greatly reduced after continuous contraction, so it presents a pathological fatigue response. In addition, patients may feel weak and weak throughout the day.
In severe cases, normal walking and activities may be affected.
2. Dry mouth.
Patients with muscle weakness may have symptoms of dry mouth, and even drinking water may not improve the response to thirst and dry mouth at all. The occurrence of this symptom may be related to abnormal autonomic function.
3. Dysphagia.
Although muscle weakness does not affect the digestive organs and does not affect the patient's appetite, symptoms of dysphagia may occur. People who want to eat but can't swallow it, and even have trouble drinking water, which may cause water to flow out of their nostrils due to choking. In severe cases, patients can only rely on nasogastric tubes to eat.
4. Respiratory tract infection.
It predisposes to the symptoms of respiratory tract infections, especially in infancy and childhood. At this time, many adverse reactions such as fever, hyperexcitement and vomiting can be manifested, and when the respiratory muscles become weak, it can lead to a great decrease in ventilation, which can lead to shortness of breath, even dyspnea, and hypoxic brain injury.
5. Facial numbness.
When the facial muscles become weak, patients are often unable to make expressions such as smiles, so there are always adverse reactions such as facial numbness and apathy. In addition, some patients may also have complications of subacute cerebellar degeneration and encephalomyelitis.
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Myasthenia is a neurology disease, which refers to the dysfunction of transmission at the neuromuscular junction caused by autoimmune causes, resulting in partial or systemic skeletal muscle weakness and easy fatigue, which will worsen after activity.
In the early stage, myasthenia gravis is mainly manifested as partial or generalized skeletal muscle weakness and fatigue, which can be aggravated after exercise and relieved with rest. Patients with proximal muscle weakness may experience weakness in the shoulder muscles, hip belt muscles, thigh muscles, and upper arm muscles. >>>More
Myasthenia gravis is a disease that is very difficult to eliminate, and ordinary methods cannot eliminate this disease. The earlier myasthenia gravis is detected, the sooner it is, the less difficult it is, and the easier it is, so it is important to diagnose it early and correctly. >>>More
For mild muscle weakness, there is no specific method, the commonly used method is medicine, and there are many drugs for muscle weakness, which need to be used under the guidance of a doctor, and can also be used through massage, acupuncture and other physiotherapy methods to alleviate symptoms, patients should also pay attention to a high-vitamin, high-protein diet.
Myasthenia gravis (MG) is an autoimmune disease caused by dysfunction of transmission at the neuromuscular junction, which is clinically manifested as partial or systemic skeletal muscle weakness and fatigue, which worsens after activity and is relieved by rest. The prevalence is 77,150,100,000, with an annual incidence of 4,111,100 million. The prevalence is greater in women than in men, about 3: >>>More
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