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Hello lz, your situation can be completely ruled out. Of course, the accuracy of the gold standard method is not as accurate as the enzyme chain method, that is, the enzyme chain method is more accurate. However, there is no so-called false negative in the test results, that is, you have HIV antibodies and cannot be tested.
There can only be false positive, that is, no HIV antibody is falsely reported as positive, the reason is that the current reagents are extremely sensitive, and it is generally better to kill a thousand by mistake than to let go of one.
What I want to clarify here is that the primary HIV screening is negative, which does not mean that there is no HIV virus, because the primary screening is to check for antibodies, and antibodies are cells that are excited by CD8 lymphocytes in the body to target the HIV virus after the body is infected with the HIV virus, and the role of the HIV antibody is to isolate and destroy the CD4 cells infected by the HIV virus and inhibit the spread of the HIV virus. It takes a while for CD8 to excite HIV antibodies to reach detectable concentrations, which is well understood as the origin of the window period. Therefore, a negative HIV screening result during the window period is not indicative.
The current detection technology window period is generally not more than 6 weeks, and the test result of LZ after 53 is after the window period, so this test result can explain the problem.
There is also a saying that the window period is 3 months and 6 months, but that was all in the early 90s, and it has long been the old imperial calendar.
As for the confirmatory experiments on the first floor, that's purely misleading, first of all, there is no window for confirmatory experiments. The confirmatory test is to directly check for the presence of HIV, and if the test result is positive, there is HIV, and if the test is negative, there is no HIV virus. There is no such thing as a window period for confirmatory experiments.
However, HIV confirmatory testing is very difficult to do because the HIV virus is so small, too small, and so fragile that it is too difficult to isolate from the blood. It's not as convenient as checking for HIV antibodies. Generally, only people who are initially screened for positive will do an HIV test to confirm it.
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Hello, the test result can be ruled out, no need to test again.
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The 53-day window period has not yet passed, and it must be 3-6 months later, subject to the results of the confirmation experiment (western blotting).
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I understand that the meaning of the question is that if you have a negative HIV antibody test 46 days after a high-risk behavior, can you rule out the possibility of having AIDS?
Generally speaking, if you become infected after a high-risk behavior, you will often go through a window period of 2 weeks to 3 months, which means that HIV antibodies cannot be detected in clinical blood tests.
However, with the advancement of technology, modern medicine generally believes that after 6 weeks of high-risk behavior, if you are infected, then the probability of being able to test positive for HIV antibodies in the blood is exceeded.
Therefore, if you are still HIV-negative after 46 days, and there are no other high-risk behaviors during these 46 days, you can have a high probability of ruling out AIDS.
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