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The anti-"O" test is usually used for streptococcal infection, and the normal result of the anti-"O" test is negative; The abnormal result is positive.
An abnormal result of the anti-"O" test means that the person may have a hemolytic streptococcal infection and may have related diseases caused by hemolytic streptococcal infection, such as tonsillitis, scarlet fever, acute glomerulonephritis, rheumatic fever, etc.
A normal result for rheumatoid factor (RF) test is negative; The abnormal result is positive. An abnormal rheumatoid factor test means that the person may have rheumatoid arthritis, systemic lupus erythematosus, or connective tissue disease.
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Clinical significance:
1. Hemolytic streptococcal infection, scarlet fever, erysipelas, streptogloccal pharyngitis, tonsillitis. It is indirectly diagnostic of rheumatic fever and acute glomerulonephritis, and can be helpful if the results of multiple tests are increasing and the erythrocyte sedimentation rate is increased.
2. A small number of non-hemolytic streptococcal infections: viral hepatitis, nephrotic syndrome, tuberculosis, connective tissue disease, subacute endocarditis, multiple myeloma, etc.
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Anti-O stands for anti-streptolysin, which is certainly a marker of streptococcal infection, and large doses of short-acting penicillin should be used**
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In general, in the case of streptococcal infection, it is often possible to cause high anti-O conditions. Don't get tired and catch a cold. Eat a light diet. Stay in a good mood.
A metabolite produced by hemolytic streptococcus can lyse red blood cells, so this product is named "O" hemolysin, and after the human body is infected with group A hemolytic streptococcus, "O" hemolysin exists in the body as an antigenic substance. To determine the amount of this antibody that neutralizes streptolysin "O", it is called the anti-streptolysin "O" test.
If it is higher than 500 units, it indicates a recent hemolytic streptococcal infection. Some patients have elevated anti-"O" resistance, but no symptoms such as joint pain, which cannot be considered to be rheumatoid arthritis, but can only indicate that they have recently had hemolytic streptococcal infection, tonsillitis, pharyngitis, scarlet fever and other diseases. However, the cause of rheumatoid arthritis is indeed related to streptococcal infection, so the anti-"O" will be elevated during the active phase of rheumatoid arthritis.
According to studies, diseases such as coxsackie-B virus, hypercholesterolemia, hemolysis, hepatitis, and nephrotic syndrome can show non-specific anti-"O" increases, but the titer is not very high, and the same is true for rheumatoid arthritis.
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Anti-streptococcal hemolysin O test, referred to as anti-O test.
Streptolysin O (streptolysin
O,SLO) is one of the metabolites of hemolytic streptococcus, which has hemolytic effect and antigenicity. 2 to 3 weeks after a human infection with hemolytic streptococcus, antibodies against streptolysin O are produced. This experiment was based on the principle of antigen-antibody neutralization test, and the reduced hemolysin O with hemolytic ability was used to detect whether there was neutralizing antibody production in serum.
If the serum antibody titer of the patient is significantly elevated, more than 400 units, it can be considered that the patient has recently been infected with hemolytic streptococcus, and it can be used to assist in the diagnosis of rheumatic fever, glomerulonephritis and other diseases.
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Acute glomerulonephritis can be detected by an antistreptococcal anti-"O" test.
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A few days ago, I took a blood test because of back pain, and the result was negative for rheumatoid, and the anti-O was positive +, and the doctor said it was rheumatism
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Examination of the joints, especially rheumatism, rheumatoid,
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Positive is a sign of streptococcal infection, it is easy to form rheumatism in people with high ASO, penicillin is commonly used to reduce inflammation, eliminate the disease ASO will decline This is the general ** method, except for penicillin allergy there are no adverse reactions.
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A positive ASO indicates a streptococcal infection.
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