Are the main causes of cancer genetics and heredity?

Hello, after many years of summary of the "All-Army Cancer Radiotherapy Center", the main causes of cancer are long-term poor lifestyle habits, bad mood, environmental pollution, Epstein-Barr virus, etc., and genes and heredity are only a small part or almost non-existent part.

Some cancers have a clear genetic predisposition, which means that if someone in the family has these cancers, then the risk of other family members will also be greatly increased. Here are some of the cancers that may be inherited and passed on to the next generation:

Breast cancer: If there is a patient with breast cancer in the family, then the probability of developing breast cancer increases significantly.

Ovarian cancer: In some families, ovarian cancer often occurs at the same time as breast cancer because the two are genetically similar. If someone in the family has ovarian cancer, then the risk of ovarian cancer also increases.

Colorectal cancer: Colorectal cancer is a relatively common genetic cancer. If there are more than one family member with colorectal cancer, then the risk of developing this cancer will be greatly increased.

Stomach cancer: If someone in the family has stomach cancer, then there is also an increased risk of stomach cancer.

Overall, cancer is a very complex disease, and its pathogenesis involves several factors, of which genetic factors are only some of the many factors. Genetic predisposition does not mean that you will have the disease, but paying attention to the influence of genetic factors on the occurrence of cancer can help you avoid risk factors and take effective preventive measures. If there is a family member with cancer, regular check-ups should be done to detect the cancer as early as possible.

In addition, a healthy lifestyle such as eating a sensible diet, exercising in a hinge province, quitting smoking and limiting alcohol, reducing stress and environmental pollution can also help reduce the risk of cancer.

Carcinoma is caused by mutations in oncogenes. The causes of oncogene mutations can be divided into two categories: one is caused by acquired natural aging, lifestyle and environmental factors, such as smoking, drinking, radiation, etc.; The other is caused by a congenital inheritance of a certain oncogene mutation.

Some types of cancer are hereditary because some oncogenes mutate. However, most cancers are caused by acquired factors and are not passed on to the next generation. About 5%-10% of cancers are directly caused by inherited genetic mutations, and it is very likely that they will be passed on to the next generation.

Inherited gene mutations can increase the risk of many types of cancer, so it's important to know your family history of cancer. If there is a lack of grandchildren in the family and patients with bowel cancer, it should be noted that routine physical examinations should be performed. Colonoscopy is recommended after the age of 40 and if there are no abnormalities, the colonoscopy should be repeated at least every 5 years.

Familial breast and ovarian cancer syndrome: caused by mutations in the BRCA1 and BRCA2 genes, inherited in an autosomal dominant manner. The risk of this genetic cancer is high, with a high risk of breast cancer and ovarian cancer of up to 60%-80% and 30%-40% in women.

Hereditary colorectal cancer: caused by a variety of genetic mutations, the most common of which is the APC gene mutation. The risk of this genetic cancer is high, with patients having a 70%-80% risk of colorectal and rectal cancer.

Hereditary gastric cancer: caused by mutations in the CDH1 gene, inherited in an autosomal dominant manner. The risk of this genetic cancer is high, with a risk of up to 70%-80% for patients developing stomach cancer.

Neurofibromatosis type 1: caused by mutations in the NF1 gene and inherited in an autosomal dominant manner. The risk of this genetic cancer is high, with a risk of up to 50% for neurofibromas and other types of tumors with bridges.

Hereditary breast cancer: caused by mutations in multiple genes, such as the Chek2 and ATM genes, and is inherited in an autosomal dominant manner. The risk of this genetic cancer is higher, with patients having up to 40% of the risk of developing breast cancer.

These cancers may be passed on to the next generation, but not every genetic mutation causes cancer. As in the case of hereditary cancer, genetic cancer is not the only risk factor for cancer, but also factors such as environment and lifestyle may also play a role in cancer risk.

Breast cancer: Variations in the BRCA1 and BRCA2 genes are genetic causes of breast cancer. Family members who have these variants have a higher risk of developing breast cancer than those who don't.

Ovarian cancer: BRCA1 and BRCA2 gene variants are also associated with an increased risk of ovarian cancer.

Colorectal cancer: Hereditary colorectal cancer is caused by genetic variants, the most common of which are those in the MLH1, MSH2, MSH6, and PMS2 genes.

Thyroid cancer fluid macro: Multiple endocrine neoplasia type 1 (MEN1) and companion type 2 (MEN2) are genetic causes of thyroid cancer.

Hereditary melanoma: Mutations in the CDKN2A gene may cause hereditary melanoma.

If someone in your family has these cancers, or if you are concerned that you may have hereditary cancers, you should talk to your doctor and genetic counselor about your family medical history and genetic risk.

1.Breast cancer: Breast cancer can be caused by a genetic mutation. BRCA1 and BRCA2 are two well-known genes involved in the inheritance of breast cancer.

2.Ovarian cancer: It is estimated that 10-15% of ovarian cancer samples are caused by mutated BRCA1 or BRCA2 genes.

3.Colorectal cancer: Some colorectal cancers are caused by familial genetic mutations, such as Lynch syndrome and FAP (multiple adenomatosis).

4.Prostate cancer: Familial inheritance of prostate cancer is often associated with the BRCA1 and BRCA2 genes.

5.Hodgkin lymphoma: This cancer can be caused by a genetic mutation. The most common of these is a mutation in the NOD2 gene.

However, it is important to note that even if there is a genetic mutation, it will not necessarily be passed on to the next generation, and even if it is inherited, it will not necessarily develop into cancer.

1.Breast Fight Adenocarcinoma.

2.Ovarian cancer.

3.Lung cancer.

4.Colorectal cancer.

5.Pancreatic cancer is cracked.

6.Gastric cancer.

7.Endometrial cancer.

8.Hepatocarcinoma.

9.Nasopharyngeal cancer.

10.Esophageal carcinoma.

Hereditary cancers are usually caused by abnormal genetic mutations that can be passed from parents to children. If a person has more than one member of their family who has a certain cancer, then the risk of developing that cancer may increase. However, even if there is no obvious history of cancer in the family, some people may carry inherited cancer genes, so genetic testing is recommended to assess an individual's risk of developing the disease.