What causes high alanine aminotransferase?

High alanine aminotransferase (GPT, ALT) is a common phenomenon in clinical practice. The liver is the largest detoxification organ in the human body, and it is very important for the human body whether this organ is normal or not. Increasing GPT is an important indicator of problems with liver function.

Among the common factors, all types of hepatitis can cause elevated GPT, which is due to:

Caused by the destruction of the liver. Some drugs, such as antineoplastic drugs and antituberculosis drugs, can cause liver damage. Heavy drinking alcohol and eating certain foods can also cause short-term damage to liver function.

GPT is mainly found in the hepatocytoplasm, and its intracellular concentration is 1000-3000 times higher than that in serum. As long as there is.

1% hepatocyte necrosis can double the serum enzymes. Therefore, GPT is recommended by the World Health Organization as the most sensitive test for liver damage. However, it is not organ-specific, and many diseases can cause it to increase.

Significant elevation is seen in acute viral hepatitis, moderate elevation is seen in chronic hepatitis, active cirrhosis, liver cancer, liver abscess, myocardial infarction, myocarditis, heart failure, etc. Therefore, the evaluation of elevated GPT should be:

Closely integrated with clinical practice. Some elevated GPT is associated with fatty liver disease and alcohol consumption. There are many hepatoprotective drugs commonly used in clinical practice.

However, the effect of some drugs can be repeated but is easy to repeat, resulting in some liver diseases that cannot be used for a long time, and a large number of liver cells are destroyed. How to protect liver cells is the key to protecting liver function.

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For example, for people who have been drinking alcohol for a long time, alanine aminotransferase will be high, because alcohol will damage people's liver cells and cause their alanine aminotransferase index to rise, followed by biliary tract diseases will also cause high alanine aminotransferase, such as the value of alanine aminotransferase will be relatively high when acute cholecystitis occurs. Secondly, long-term high alanine aminotransferase is likely to be caused by viral hepatitis, so it must be caused as soon as possible.

Alanine aminotransferase exists in the cells of liver, heart, skeletal muscle and kidney, and the amount of alanine aminotransferase contained in each organ is the largest in hepatocytes. Therefore, whenever hepatocytes are damaged, such as hepatocyte degeneration and necrosis, alanine aminotransferase in hepatocytes is released into the blood, which is the most common cause of elevated serum alanine aminotransferase.

Suggestion: If the aminotransferase is temporarily high, hepatitis B is normal in two pairs. You don't have to be nervous, and you don't need to**. Just pay attention to a balanced diet, don't overeat, drink less, stay up late, eat less foods that are too high in fat, and adjust for a while.

If alanine aminotransferase is still high after a period of time, you can take liver-protecting Chinese medicine to recuperate.

1. Recheck and eliminate errors again; 2. Drug-induced liver injury can be further ruled out (are there any new drugs added recently?). ) or fatty liver (ultrasound excludes fatty liver) or viral hepatitis (hepatitis A, hepatitis B, etc.).

Alcohol consumption, staying up late, medications, fatigue, etc. may all be elevated for reexamination.

Abnormal liver function and high aminotransferases can be caused by several reasons:

1. Viral hepatitis, such as hepatitis A, hepatitis B, hepatitis C, etc., may cause transaminases to rise to a higher level, because the virus will trigger the body's immune response, causing the immune system to harm the liver, thereby causing liver cell damage and elevated aminotransferases.

2.Non-viral hepatitis, such as alcoholic liver disease, drug-induced hepatitis, fatty liver, etc., can cause inflammatory damage to the liver, which can harm liver cells, thereby causing elevated aminotransferases.

3.Liver diseases caused by various hepatitis, such as liver cirrhosis and liver cancer, are accompanied by liver damage, and the patient's liver damage is severe, which can be reflected through aminotransferases.

4.Incorrect habits in daily life will also cause an increase in transaminases, such as unreasonable diet, lack of sleep, taking drugs or excessive exercise, etc., which will cause a short-term increase in transaminases, which can be recovered if you pay more attention.

Hello! Your alanine aminotransferase is high, and there are many reasons for high aminotransferase, such as cold, fever, drinking, gastrointestinal diseases, poor rest, etc., and you can't single high aminotransferase to determine that hepatitis is suspicious.

Wishing you happiness and good health!

Elevated aminotransferases are mainly due to negative problems in the liver and heart. It is recommended for your branch to disturb the ticket segment of hepatitis B, hepatitis C, and cardiac enzymes to determine which may cause no. I also like to take cold medicine, and drinking a lot of alcohol can cause transient aminotransferase to rise and burn high.

There are many reasons for high alanine aminotransferase, such as: acute hepatitis, taking drugs (especially drugs that damage the liver), long-term drinking or drinking a large dose at a time, and some biliary diseases, it is recommended to rest for 3 days, do not drink alcohol and stay up late with medicine, and then go to the hospital for reexamination, if it is still higher than 2 times, you need to further find the cause.

It is mainly the liver that is damaged and releases alanine aminotransferase into the blood, resulting in high levels of alanine aminotransferase in the blood.

There are many causes, mainly viral hepatitis, drug damage, alcoholic liver disease, and many more.

High alanine aminotransferase is seen in the following conditions:

1 Viral hepatitis is the most common disease that causes elevated aminotransferases, and all kinds of acute and chronic viral hepatitis can lead to elevated aminotransferases.

2 Toxic hepatitis A variety of drugs and chemicals can cause elevated aminotransferases, but after stopping the drug, the transaminases can return to normal.

3 Alanine aminotransferase is also elevated in heavy or long-term drinkers.

4 When liver cirrhosis and liver cancer cirrhosis are active, aminotransferases are higher than normal levels, and they should be active**.

5. Acute attack of cholecystitis and cholelithiasis of biliary tract diseases often cause fever, abdominal pain, nausea, vomiting, jaundice, elevated blood bilirubin and aminotransferases.

6 In the case of acute myocardial infarction, myocarditis and heart failure of heart disease, alanine aminotransferase and aspartate aminotransferase are elevated, and patients often have chest pain, palpitations, shortness of breath and edema. Cardiac examination has positive signs and an abnormal ECG.

7 Some other infectious diseases, such as pneumonia, typhoid, tuberculosis, infectious mononucleosis, etc., have elevated aminotransferases, but these diseases have typical clinical manifestations and can be diagnosed with the help of laboratory tests. In addition, acute soft tissue injury, strenuous exercise, and transient elevation of aminotransferases may also occur. Therefore, you need to go to the hospital for a more comprehensive examination to find out the cause and deal with it in time.

Hello, there are many reasons for high alanine aminotransferase, such as: acute hepatitis, taking drugs (especially drugs that damage the liver), long-term drinking or drinking a large dose at one time, as well as some biliary diseases, heart failure in heart disease, fever and other conditions, can cause high alanine aminotransferase.

The immediate cause of high alanine aminotransferase is the rupture of hepatocytes, which release intracellular alanine aminotransferase. There are many causes of elevated glutamate, such as after strenuous exercise, drunkenness, acute hepatitis, biliary tract diseases and fatty liver. Certain drugs can also cause transient elevated alamine.

If there is a problem with the heart, it must be accompanied by a large increase in aspartate aminotransferase.

Physical examination of alanine aminotransferase greater than 40 is considered high, but the real liver damage is generally more than 100.

Elevated aminotransferases are mainly due to negative problems in the liver and heart. Recommend your check for hepatitis B, hepatitis C, and cardiac enzymes to determine which ones may cause not. He also likes to take cold medicines, and heavy alcohol consumption can cause transient elevation of aminotransferases.

There are many reasons for high alanine aminotransferase, such as: acute hepatitis, taking drugs (especially drugs that damage the liver), long-term alcohol consumption or drinking large doses at one time, as well as heart failure in some biliary diseases, heart disease, fever and other conditions.

The cause of high aminotransferases may be related to problems with the liver itself, such as viral hepatitis or heavy and regular alcohol consumption and poor rest. So you have to find the reason and target the cause. Usually, you must be careful not to overwork, abstain from alcohol, and do not take drugs that damage the liver.

Drink plenty of water and eat more vegetables and fruits. If you want to eat, you can eat some: Compound vitamin B vitamin C inosine tablets liver protection**, but don't take too much medicine, too much medicine will cause liver damage.