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A study in the Journal of Clinical Endocrinology and Metabolism found that most obese people always do not feel full, and always feel that "not eating enough" may be caused by the failure of glucagon in the body. Glucagon, a hormone that can raise blood glucose, functions in the opposite way to insulin, and previous studies have shown that glucagon can induce feelings of fullness. In the study, researchers from the Medical Center at the University of Berlin Saritai in Germany conducted a comparative trial of 11 obese people, 13 patients with diabetes (inadequate insulin secretion) and 13 lean people, randomly injected them with glucagon or a placebo, and subsequently measured their satiety and ghrelin levels.
The results showed that patients with type diabetes and thin people who could not produce insulin normally in their bodies showed a significant feeling of fullness and decreased ghrelin levels after glucagon injection. In contrast, there was little difference in the degree of satiety between glucagon and placebo injections, suggesting that obese people were no longer sensitive to glucagon, which controls appetite.
Dr. Carol Ross of Imperial College London has always been interested in the study of obesity, and their team found that the peak and duration of satiety hormones in obese people were lower than those of normal weight, and the peak and duration of satiety hormones were lower than those of normal weight people. On the other hand, ghrelin (the hormone that increases hunger) in normal people will drop immediately after a meal, and it will start to rise after a period of time, so normal people's hunger will fluctuate regularly every day. But obese patients have low levels of ghrelin that are very inactive, and when they eat, the level of ghrelin stays at a low level, and then the level of ghrelin does not change at all that day.
Therefore, obese people usually do not have a strong sense of satiety and hunger, which may be the reason why many obese people around us always complain that they are not very hungry, but they keep eating as soon as they pick up food, because they always do not feel full.
The above studies have shown that abnormal hormone secretion and action may be the cause of obese patients always feeling "not enough", of course, the specific mechanism needs to be further studied.
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Because their minds are all about eating.
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Many obese people always have the feeling of "not having enough to eat", and they can't suppress their appetite even after eating. The latest research has found that the reason for this is that glucagon, which controls appetite in obese people, has become ineffective. Glucagon is a hormone that controls glucose metabolism and regulates blood sugar, acting the opposite of insulin.
When blood sugar is low, glucagon secretion increases and insulin decreases, and when blood sugar is high, glucagon secretion decreases and insulin increases. In addition, glucagon can also affect ghrelin, a key hormone in the body that regulates food intake, controlling appetite by regulating the body's hunger feelings. Researchers at the Scharité University Medical Center in Berlin, Germany, conducted a comparative trial of 11 obese people, 13 people with type I diabetes, and 13 lean people, randomly injected them with glucagon or a placebo, and then measured their satiety and ghrelin levels.
The results showed that there was little difference in the degree of satiety between glucagon and placebo injections, indicating that their bodies were no longer sensitive to glucagon. In contrast, diabetics and thin people who do not produce insulin normally in their bodies report a noticeable feeling of fullness after glucagon injections, and the hormone can be detected even after 24 hours. The researchers said that the reasons for the failure of glucagon to regulate appetite in obese people need further research, but the finding provides new ideas for obesity and diabetes.
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First of all, in your case, you should go to the hospital to check whether there are some diseases in your body, because it is very much back** also answers that you are the cause of weight loss.
Secondly, people who have been eating and not getting fat are not necessarily physical, if it is a genetic reason, it is difficult to get fat.
There is also the possibility that the absorption of one's own stomach and intestines is not good, and the food cannot be absorbed in time at all, which is also a major reason.
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I heard that eating placenta is more effective, but it is a little nauseous.
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Please let me know when you have the answer! I object 176 ......Weight 107 ......I always like to drink tea. It is also important not to eat at night, which is not good for your health! I felt like I was protecting him.
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Eat more at night and don't exercise after eating.
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First of all, he has a big belly and can pretend, and secondly, even if he is full, he still wants to eat when he sees the food.
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That's why you're fat, and you're fat because you have a strong absorption capacity, so what you eat, he's absorbing quickly, he's absorbing fast, and he's naturally hungry all the time.
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Generally, fat people have bigger stomachs than usual!
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Because the belly is too big, the stomach is too big, and it's chubby. Fat burns slowly, and what you eat is digested quickly.
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The stomach is large and the digestive function is strong.
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Eating more and more again and again has made my stomach bigger.
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Because the food eaten is absorbed by fat.
The orange is round,and the orange cat is also round haha
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