Down s Comprehensive Screening 200, Down s Comprehensive Screening

It must be done, although amniocentesis has an effect on the fetus, but within the acceptable range, the lesser of two evils. If you don't do it, no one knows what the outcome will be, and if there is a result that you don't want to see, it's too late to regret it.

Now there are two options:

1. Don't want this child, because the risk has not yet been determined, and I don't know if there are any adverse symptoms.

2. According to the plan proposed by the big hospital.

Why: Tell a true story, I know a Guangxi, her two in-laws have mild thalassemia in their births, when she was pregnant, she went to do a physical examination, but did not do this Down syndrome test at that time, and now she has a leukemia child, now she is more than 5 years old, and she has to go to the hospital to replenish blood twice a month, except for the money now she removes herself, which costs about 1500 months, and the hospital said that it will cost 300,000 yuan at one time to do a bone marrow transplant, and she does not have this condition now (there is not so much money at all), I had to follow the plan of only blood transfusion every month, I asked her, she said there was no way, it was difficult to let the child die, I asked her, why was not tested at that time, knowing that thalassemia is a high incidence in Guangdong and Guangxi, she said, she did not think so much at that time. She now knows that it is too late, not only is the money from her two in-laws' part-time jobs used to suffer on their children, but she has not put on a good dress and has not enjoyed a good day.

So the landlord should think twice!

Under normal circumstances, most of the high-risk patients are also determined to be low-risk after amniocentesis, so the examination is mostly to buy peace of mind;

Amniocentesis carries a risk of infection, but it is also a relatively low risk;

It is said that some large hospitals have a safer solution without amniocentesis, but according to colleagues in Beijing, I don't know the situation in Guangdong.

In short, ask a few more experts for advice and decide for yourself. Don't worry too much, the probability of bad situations happening is accidental, and a good mood is also good for the baby.

The Down's screening was not accurate, I did it twice, once at 1:150 and the second time at 1:120, the doctor said that I would do amniocentesis, and the operation sheet was opened, but in the end I didn't do it, now my son is one year and twenty days old, he can walk, all aspects are normal, and he is very naughty.

I also checked a lot of information at the time, and the probability of this is very low, especially emphasizing: if you and your wife and your wife do not have a history of this disease, it is generally fine. And I heard that many hospitals do not do Down's screening, because the results are calculated based on multiple data, which can be said to be not very accurate.

Therefore, it is most important for expectant mothers to maintain an optimistic mood. Of course, if you are really not at ease, you can change a hospital and then do Down's, you must change a hospital, of course, you have to go to a regular hospital, if the result is still not very good, and you are always worried about this problem, then you can still consider doing amniocentesis to be safer, in addition, there is a time limit for doing this operation, make a decision as soon as possible. If you go, then do it, it's not a big deal, now that science is so developed, if you don't go then don't think about it, the mood of the expectant mother is very important.

Finally, I wish you a lively, cute and healthy baby.

It is recommended that you change hospitals to do a new Down screening to prevent the possibility of inaccurate results of the previous test.

Amniocentesis may have adverse effects on the fetus, so it is best to consider it if repeated Down syndrome screening is not normal.

Landlord, this kind of thing has to be decided by yourself, and others can't help it. You have to make up your mind as soon as possible, or the family will really go crazy!

If the landlord is really not at ease, he still has to go to a large professional maternal and infant health hospital to do it.

But what does Tang Sieve say? Many of the ingredients together are calculated by probability. It's like buying a lottery ticket, you are unlucky and you win.

No need to do amniotic fluid puncture, only 25, the baby must have no problem.

My sister 21 trisomy 1,60 and then changed hospitals, and they all recommended to go to amniotic fluid pumping, but the health is still how to admit it.

On the 11th of this month, a lovely baby girl was born.

I think it's better to go to a big hospital to find experts and professors, and I can't be sloppy.

The risk cut-off value for Down syndrome is 1 270, greater than this value is high risk, below this value is low risk, you are now 1 135, higher than 1 270, so it is high risk, which means that your child has a higher probability of developing Down syndrome.

The rest of the trisomy 18, neural tube defects, and so on are normal.

The accuracy rate of Tang Sieve is only 70, and more than 90 of the high-risk results of Tang Sieve are normal, while the low-risk results of Tang Sieve may be the real Tang's children.

To diagnose a child with Down's syndrome, the most common method is amniocentesis, the accuracy of amniocentesis is as high as 99, and the disadvantage is that there is a risk of miscarriage.

At present, there is a new technology, called non-invasive prenatal genetic testing technology, which only needs to draw the mother's venous blood, extract free DNA (including fetal free DNA), and through high-throughput sequencing technology and bioinformatics analysis, it can detect fetal chromosomal abnormalities with an accuracy rate of more than 99, and there is no risk to the fetus (because it only draws the blood on the mother's arm).

However, this technology is currently only being promoted in Beijing, Wuhan, Chongqing, Shenzhen, Guangzhou and other cities, and Chengdu has not yet done so.

Personally, it is recommended that you go for an amniocentesis, otherwise you will be worried throughout the pregnancy, which is not good for yourself and your baby. Although amniocentesis has certain risks, it is a small probability event.

Generally, after screening for Down's syndrome, more than 98% of patients have no problem after amniocentesis;

Therefore, it is recommended that you do a non-invasive prenatal genetic test first, based on your current gestational age, even if the non-invasive test is still positive, you still have time to do further diagnosis.

Noninvasive prenatal genetic testing is low-risk, and you can continue your pregnancy.

Non-invasive prenatal testing, Southwest Hospital can do it now.

Amniocentesis is generally recommended. I did it too, and the results were good.

The danger is not big, and now it is done under the supervision of B ultrasound, and it will not hurt the baby.

However, it is always a minor operation, and I think it is a little painful, so pay attention to rest after the operation. Discuss it with your family if you want to do it or not.

Down's screening is a detection method that calculates the risk factor of giving birth to a fetus with birth defects by sampling the serum of pregnant women, detecting the concentration of alpha-fetal protein, chorionic gonadotropin and free estriol in the maternal serum, and combining the expected date of delivery, weight, age, weight and gestational age at the time of blood collection.

What is Down Syndrome?

Identification of high-risk pregnant women with certain birth defects from pregnant women through economical, simple and non-invasive testing methods in order to further confirm the diagnosis and minimize the birth rate of abnormal fetuses. Prenatal screening usually refers to the detection of high-risk pregnant women who are pregnant with birth defects through the detection of maternal serum markers. The best time to carry out screening is the 9th and 14th week of pregnancy, which is called first trimester screening, and if you miss this time period, you need to enter the second trimester screening, although the risk can also be calculated, but if the final diagnosis is positive, it will cause greater damage to the mother.

Screening results are usually available within a week after the blood draw, and there is no need to panic if the results are high-risk, as further chorionic villus biopsy (early), amniocentesis, and fetal chromosome examination (intermediate) are required to confirm the diagnosis.

Why Get Screened for Down Syndrome?

Children with Down syndrome have severe intellectual disability, congenital stupidity, dementia with protruding tongue, inability to take care of themselves, and complex cardiovascular diseases, which require long-term care from their families, which will cause great mental and economic burden to their families.

Who will give birth to "Down's child"?

Down syndrome is an episodic condition, so every pregnant woman has the potential to have a "Down syndrome". The chance of having a baby with Down syndrome increases with the age of the pregnant woman.

How is it screened? During the Down syndrome screening, you should not eat or drink after 12 p.m. the night before the test, and come to the hospital the next morning on an empty stomach for the test. In addition, the examination is also related to the menstrual cycle, weight, height, exact gestational age, gestational age, and it is best to consult your doctor about other preparations before the examination.

Screening includes the sampling of pregnant women's serum, the detection of pregnancy-associated plasma protein A (PAPP-A), free HCGB subunits (two early years) or alpha-fetal protein (AFP) and chorionic gonadotropin (HCG) and free estriol (UE3) in maternal serum, combined with the expected date of delivery, weight, age and gestational age at the time of blood collection, to calculate the risk factor of "Down syndrome", which can detect 80% of Down's syndrome children.

Methods and outcome evaluation of prenatal screening of maternal serum.

In the detection of multiple indicators of maternal serum prenatal screening, radioimmunity, enzymatic immunoimmunization, time-resolved immunofluorescence and chemiluminescence methods are generally used. Due to the large variation in the results of radioimmunoassay and enzyme immunoassay, time-resolved immunofluorescence and chemiluminescence methods are generally used, and the national recommended time-resolved immunofluorescence method.

Precautions. During prenatal screening, pregnant women need to provide more detailed personal information, including date of birth, last menstrual period, weight, whether insulin-dependent diabetes, twins, smoking, abnormal pregnancy history, etc., because the risk rate statistics of screening need to be corrected according to the above factors, so it is also very important to fill in the laboratory test form before blood drawing.

High-risk groups who are prone to having Down's syndrome.

1. Before and after pregnancy, pregnant women have a history of viral infection, such as influenza, rubella, etc.;

2. At the time of conception, one of the husband and wife has chromosomal abnormalities;

3. One of the spouses is older;

4. Before and after pregnancy, pregnant women take teratogenic drugs, such as tetracycline, etc.;

5. One of the husband and wife has been working under a radioactive screen or in a contaminated environment for a long time;

6. Pregnant women with a history of habitual miscarriage, premature birth or stillbirth;

7. One of the husband and wife keeps pets for a long time.

The Chinese University of Hong Kong has developed the latest technology for Down syndrome screening, which can be detected by blood drawing at 13 weeks of pregnancy or above, which is more than the 21 signs commonly used in clinical practice, and it is safe, only from the arm, which is obviously safer than invasive amniocentesis and does not have to wait so long. It has been approved for use as a clinical prenatal examination technique with an accuracy rate of nearly 100%. You can click on my registration name to browse my space.

Since the city women and children suggested going to a big hospital to do amniocentesis, it means that the technology is insufficient and it is not accurate.

I went to the Provincial People's Hospital for maternal and child health care, and the result was 1:2400, low-risk, and there was no need to do amniocentesis. Just believe it.

Hello, your results are good, no risk, rest assured.

The view is the comparison of your test results with the reference range.

For example, these three key points:

These three items are not good, and your results are not in the reference range, which means that neither you nor the child are bad.

If the test results are within this reference range, there is a problem.

This result shows that the baby does not have the risk of Down's, this is preliminary, if you want to be diagnosed to do amniocentesis, you are young and generally do not need it.

This kind of risk screening, the cut-off value is 1 275, that is to say, as long as the probability is less than 1 275, it is a low risk, vice versa, the high risk of Down syndrome is indeed related to the age of pregnancy, the older the mother, the greater the chance of Down's child, but it is not possible to judge whether the child is really a problem based on this number.

In fact, even if it is one in tens of thousands, who dares to guarantee that one in ten thousand is not himself?

Conversely. Even a 1 in 10 chance of having a healthy child is 9 in 10, so about 90% of high-risk pregnant women in real life will have a healthy child. Therefore, your doctor may recommend an amniocentesis.

At present, the technology of amniocentesis should be relatively mature, because the abortion rate of puncture is about 1 in 3,000, which is also a very low probability, and generally does not affect the fetus, but it should be noted that after amniocentesis, it is necessary to culture observation and DNA detection of the fetal residue in the amniotic fluid, so there is a certain probability of failure [the failure probability is not low], that is to say, once the test fails, the money will be spent in vain, and the puncture will continue to be carried out if the test continues...

Therefore, you have to weigh the pros and cons yourself, and if you ask the doctor, the doctor will only tell you to decide, after all, no one can afford to take the responsibility here.

You are at high risk, that is, the probability of giving birth to a baby with trisomy 21 is 1:116, which is statistically significant, and amniocentesis is recommended to confirm the diagnosis!