Chinese herbal medicine pays attention to compatibility, where does the experience come from?

From the Qin, Han and Qing dynasties, there are as many as 400 kinds of herbal works. However, the composition of traditional Chinese medicine is relatively complex, and it cannot be explained by science at all. But it works.

I think that the ingredients of Western medicine are relatively simple, and scientific experiments are relatively simple and clear, while the ingredients of traditional Chinese medicine are complex, so experiments cannot be done. To put it simply, if you use orthogonal experiments, the results of L2,2 and L10,10 are of course different, and then consider different indicators, how do you determine the results? In my opinion, it is not that Chinese medicine cannot be scientific, but that it cannot be scientificized with the current science, because our ancestors are too advanced.

Chinese herbal medicine is first of all to attribute the characteristics of medicine to the scriptures. When seeing a doctor, people are also diagnosed with menstrual periods, so there are different treatments for the same disease, and different treatments for different diseases.

The qualitative attribution of herbal medicine and the determination of menstrual symptoms are both summarized by long-term clinical practice. These experiences are science.

Take animals and humans as an example, scientifically speaking, humans and animals are actually the same, both are carbon-based organisms, but science will not admit that humans and animals are the same species, because humans and animals have different habits from ancient times to the present, and genetic factors are different, this is science, and science still comes from experience. On the basis of having a computer, modern science still needs to verify the correctness of the conclusions through practical operations.

Traditional Chinese medicine (TCM) and Chinese herbal medicine are very clinical sciences, and it is impossible to accumulate large-scale experience to develop TCM under modern circumstances. The compatibility of Chinese medicine and Chinese herbal medicine, experience comes from **, and now we can draw conclusions, which come from the 5000-year war history of China, when a discipline is not outdated for 5000 years, then it can be classified as science.

(1) Nineteen fears:

Sulfur is afraid of Pu nitrate, mercury is afraid of arsenic, wolf poison is afraid of Tantra monks, croton is afraid of petunias, cloves are afraid of tulip, Sichuan Wu, grass Wu is afraid of rhino horn, tooth nitrate is afraid of three edges, Guan Gui is afraid of stone fat, ginseng is afraid of five spirit fat.

2) Eighteen anti:

licorice anti-gansui, euphorbia, seaweed, coriander; Aconitum anti-fritillary, melon wilt, banxia, white sage, white and; Quinoa anti-ginseng, sand ginseng, salvia, scutellaria, asarium, peony.

There are slight discrepancies in the subsequent "Compendium of Materia Medica" and "Pharmacology" and other books, but they are not as widely recognized and disseminated as the Eighteen Anti and Nineteen Fearful Songs.

Shennong's Materia Medica: Preface points out that "do not use the opposite and the opposite", "if it is poisonous, it is appropriate to make it, you can use those who fear each other and kill each other, and do not use it". Since the Song Dynasty, the relationship of "mutual fear" has also been listed as a taboo, which is confused with "mutual evil". Therefore, the concept of "nineteen fears" is not the same as the meaning of "mutual fear" of one of the "seven feelings" discussed in the section "compatibility".

Some of the "Nineteen Fears" and "Eighteen Anti" medicines are somewhat different from the actual application, and the doctors of the past dynasties have also discussed them, citing ancient prescriptions as evidence to prove that some drugs can still be used together. For example, the croton in the induction pill is used with morning glory; Gansui Banxia soup is juxtaposed with licorice and Gansui; Disperse swelling and ulcer soup, seaweed and jade pot soup, etc., are combined with licorice and seaweed; The Ten Spices Rejuvenation Pill is a combination of cloves and tulips; The big active Dan aconitum is used with rhino horn and so on. Some experimental studies have preliminarily shown that when the two drugs are combined, the toxicity mainly depends on the proportion of licorice, and if the dose of licorice is equal or greater than that of Gansui, the toxicity is greater; For example, fritillary and banxia were compatible with Aconitum respectively, and no obvious enhancement of toxicity was observed.

The combination of asarum and veratrol can lead to poisoning and death in experimental animals. Since the study of the "19 fears" and the "18 antis" still needs to be further carried out in terms of experiments and observations, and their mechanisms should be studied, a cautious attitude should be adopted at present. Generally speaking, for some of these drugs, if there is no sufficient basis and application experience, it is still necessary to avoid blind cooperation.

The use of two or more drugs in the same animal at the same time or in a short period of time is called a combination of drugs or a combination of internal drugs. The aim is to enhance the efficacy of the treatment and reduce adverse effects for the sake of different symptoms or comorbidities. After the compatibility of drugs, the drug effect is enhanced, and the synergistic effect is enhanced; After the compatibility of drugs, the effect of the drug is weakened.

It is a combination of three parts of medicine, a combination of Chinese herbal medicines, according to the condition, medicinal properties and requirements to be correctly configured, the allocation of contraindications, drug contraindications, dosage and dosage and other main contents.

Compatibility: 1 Mutual Requirements.

That is, the combination of drugs with similar performance and efficacy can enhance their original efficacy. For example, the combination of gypsum and Zhimu can significantly enhance the effect of clearing heat and disliking fire; The combination of rhubarb and miscanthus can significantly enhance the effect of attacking diarrheal heat.

2 Phase. That is, there is a certain common drug in terms of performance and efficacy, and one drug is the main drug, and the other drug is supplemented, which can improve the efficacy of the main drug. For example, when the astragalus membranaceus that replenishes qi and water and the poria cocos that improves water and strengthens the spleen are combined, Poria cocos can improve the best effect of astragalus to replenish qi and water; When the skullcap that clears heat and fires is combined with the rhubarb that kills the heat, the rhubarb can improve the effect of the skullcap on clearing heat and dispelling fire.

3 Fear of each other. That is, the toxic reaction of one drug or *** can be mitigated or eliminated by another drug. For example, the toxic properties of Shengbanxia and Shengnanxing are reduced and eliminated by ginger, so it is said that Shengbanxia and Shengnanxing are afraid of ginger.

4 Kill each other. That is, one drug can reduce or eliminate the toxicity of another drug. For example, ginger can reduce or eliminate the toxicity of raw Banxia and Shengnanxing, so it is said that ginger kills the poison of Shengbanxia and Shengnanxing. It can be seen from this that fear and kill each other are actually two terms of the same compatibility relationship, which are in terms of mutual treatment between drugs.

5 Evil. That is, when two drugs are combined, one drug acts with the other drug and the original efficacy is reduced, or even the drug is lost. For example, ginseng is evil sulforaphane seeds, because sulforaphane seeds can weaken the qi-replenishing effect of ginseng.

6 On the contrary. That is, the combination of two drugs can produce toxic reactions or ***. For example, some drugs in the "Eighteen Anti" and "Nineteen Fears" (see "Drug Contraindications").

To put it simply, it is to set a few flavors of Chinese medicine, how much, and match them into a team, ** relative diseases.

The compatibility relationship of various Chinese medicines can be summarized as follows; There is a one-way person who is a kind of medicine. The opposite is the combination of two drugs with similar efficacy to increase the efficacy of the original drug. Such as ephedra with cinnamon branches.

One drug is the main one and the other is supplemented, and the auxiliary drug can improve the efficacy of the main drug. For example, skullcap with Poria cocos to treat spleen deficiency and edema. The toxicity of one drug is inhibited by another drug, such as Banxia phobia ginger.

Killing each other means that one drug can eliminate the poison of another drug. Such as sheep blood kills hook kiss poison. The one is one drug that destroys the efficacy of another, such as ginseng sulforaphane.

On the contrary, the use of two drugs together can produce violent poison, such as licorice anti-gansui, which has eighteen anti-and nineteen fears.

Hehe, it's like a chef with spices.

Legend has it that the ancestor of traditional Chinese medicine, Yi Yin, was the prime minister of the Shang Dynasty and a cook. Therefore, Chinese medicine prescriptions are called "soup". It's from the chef.

The two chefs use smoked sauce and vinegar to blend the ingredients, why is the dish made by this chef not as good as the other chef?

Similarly, the two traditional Chinese medicines use those traditional Chinese medicines in the pharmacy, but the effects of the traditional Chinese medicines are different.

Let's show you the eighteen antis and nineteen fears of traditional Chinese medicine: these drugs cannot be used together.

The eighteen anti-lists three groups of opposite drugs, namely: licorice anti-gansui, euphorbia, seaweed, and coriander; Aconitum (Chuanwu, Aconite, Caowu) anti-Banxia, Guaron (whole melon, melon skin, melon kernel, smallpox pollen), fritillary (Chuanbei, Zhebei), Baizhi, Baiji; Quinoa anti-ginseng, Nansha ginseng, salvia, scutellaria, sophora, fine puncture, peony (red peony, white peony).

The nineteen fears are sulfur and phobia, arsenic and arsenic, wolf venom and tantric monks, croton and petunia, cloves and tulip, Sichuan and grass and rhino horns, tooth nitrate and triangular edges, Guan Gui and ginseng.

There are too many of these, you can look at pharmacy, and then look at "Soup Song".

Answer]: A After the use of traditional Chinese medicine, it can produce synergistic, bright staring inhibition and antagonistic effects. Synergistic and inhibitory effects can improve drug efficacy or alleviate drug toxicity is something we should take advantage of in our medical practice.

The antagonistic effect refers to the fact that after the two drugs are used together, they may have harmful effects on the human body, which is what we should try to avoid in the practice of medical pants, that is, compatibility contraindications.

The combination of two or more drugs is called compatibility. Traditional Chinese medicine is often used in clinical practice. The purpose of compatibility is to make the drug better exert its efficacy, stop its adverse effects, and take care of more complex syndromes.

Some drugs with similar properties promote each other's efficacy after being combined, called "Xiangsu", such as Cork and Zhimu. After the combination of two or more drugs with different functions, the effect can be better, which is called "Xiangxiang", such as coltsfoot and almonds. When two drugs are combined, one drug is inhibited by the other drug, and it is enough to reduce or eliminate its toxicity or potency, it is called "Xiangti", such as Banxia Phobia ginger.

One drug can contain the efficacy of another drug, called "phase evil", such as ginger evil skullcap. One drug can eliminate the toxic reaction of another drug, called "mutual killing", such as mung bean killing croton poison. When the two drugs are combined, a violent attack can occur, which is called "opposite", such as aconitum anti-banxia.

Evil and opposite, it is a taboo of compatibility. However, it has recently been reported that the appropriate use of the combination of opposite drugs can change the "contraindication" to "radical", so as to achieve unexpected effects on some incurable diseases, but further research is needed.

Although most of the drugs are used in compatibility, there are also a few that are used exclusively, called "single line", such as single ginseng soup, licorice soup, etc.