What is non homologous recombination, the concept of homologous recombination

Homologous recombination: Recombination between or within DNA molecules.

Principle of homologous recombination: Recombination between or within DNA molecules containing homologous sequences on non-sister chromatids or on the same chromosome.

Homologous recombination requires a series of protein catalyses, such as RECA, RECBCD, RECF, RECO, and RECR in prokaryotic cells. and rad51, mre11-rad50 and so on in eukaryotic cells.

Homologous recombination reactions are usually divided into three stages based on the formation and resolution of crossover molecules or holliday structures, namely the pre-associative stage, synapsanism, and resolution of holliday structures.

Homologous recombination can exchange DNA molecules in both directions or transfer DNA molecules in one direction, the latter is also known as gene switching. Since homologous recombination is strictly dependent on the homology between molecules, homologous recombination in prokaryotes usually occurs during DNA replication, while homologous recombination in eukaryotic spiked organisms is common after the S phase of the cell cycle.

The incorrect thing about homologous recombination is: ().

a.Homologous recombination does not require a specific DNA sequence.

b.Homologous recombination requires that the sequence between the two molecules must be identical.

It has endonuclease and helicase activity.

The formation of intermediates is an important step abrupt step of homologous recombination.

e.DNA is required to be involved in the enzyme of hunger and hunger.

The answer is b

How does it work?

Homologus recombination is a recombination that occurs between or within a sister chromatid or a DNA molecule containing a homologous sequence on the same chromosome. Homologous recombination requires a series of protein catalyses, such as RECA, RECBCD, RECF, RECO, and RECR in prokaryotic cells. and rad51, mre11-rad50 and so on in eukaryotic cells. Homologous recombination reactions are usually divided into three stages based on the formation and resolution of crossover molecules or holiday juncture structures, namely the pre-association stage, association formation, and holiday structure resolution.

Homologous recombination reactions are strictly dependent on homology between DNA molecules, with 100% recombination between DNA molecules commonly found in homologous recombination between sister chromosomes called Homologous recombination, while recombination between or within DNA molecules that are less than 100% homologous is called hemologus recombination. The latter can be proteins responsible for base mismatching, such as muts in prokaryotic cells or MSH2-3 in eukaryotic cells". Homologous recombination can exchange DNA molecules in both directions or transfer DNA molecules in one direction, the latter is also known as gene conversion.

Since homologous recombination is strictly dependent on homology between molecules, homologous recombination in prokaryotes usually occurs during DNA replication, while homologous recombination in eukaryotes is common after the S phase of the cell cycle.

It is recommended to take a look at the English version of Waston's Molecular Biology of Genes, which has a detailed description of the homologous recombination mechanisms of eukaryotes and prokaryotes.

It is minus one or mid-term, when there are 2 chromosome sets in the cell. One-to-one correspondence, every two chromosomes of this one-to-one correspondence are called homologous chromosomes, and the chromosomes that are not homologous chromosomes are called non-homologous chromosomes, and the chromosomes in these two chromosome groups are recombined into two chromosome groups that are also one-to-one correspondence is called non-homologous chromosome recombination, and I will explain it to you with letters.

For example, chromosome group 1 uses ABCD to represent 4 chromosomes, and chromosome group 2 uses ABCD to represent the corresponding 4 staining questions, and after recombination, it can be changed to abcd, abcd or ABCD, ABCD, etc., where A and A are homologous, and all chromosomes of A and non-A are non-homologous.