What are rare ginsenosides? What are ginseng fruit saponins and what are their effects

Rare ginsenosides, which are metabolic derivatives or transformation derivatives of prototype ginsenosides, are known as rare ginsenosides because they only exist in processed ginseng such as wild ginseng, red ginseng and black ginseng, and the content is very low (only containing 10,000 grades), which has more diverse and powerful biological activity, and can be called the "noble" in the ginsenoside family, including RG3, RG5, RH2, APPD, RK2, RH3 and other components.

What is the conversion rate of rare ginsenosides?

To understand rare ginsenosides, first understand ginsenosides. Ginsenosides are tetracyclic triterpenoid saponins extracted by scientists from plants of the Pentaceae family (such as American ginseng, ginseng, Korean ginseng, etc.). Since the 60s of the last century, ginsenosides have become a hot field of anti-cancer natural medicine research due to the discovery of anti-cancer activity by scientists to have anti-cancer activities.

Rare ginsenosides are more active.

In the process of research, scientists found that ginsenosides are transformed secondary metabolic derivatives with stronger biological activity. Therefore, scientists named this secondary metabolic derivative "rare ginsenosides", and the ginsenosides directly extracted from the plants of the Pentaceae family became "prototype ginsenosides".

Due to the stronger anti-cancer activity of rare ginsenosides, the research focus on ginsenosides has gradually focused on rare ginsenosides. After more than half a century of research, scientists have discovered more than 60 rare ginsenosides, including RK2, RG3, RH2, RG5, RK1, RK3, RH1, RH3, RH4, APPT, APPD, etc. The anti-cancer effects of these rare ginsenosides vary.

Rare ginsenosides are not just Rh2 and Rg3

Due to the different degrees of research, development and application of rare ginsenosides, people's understanding of rare ginsenosides is also different. In China, rare ginsenosides RH2 and RG3 are currently the most widely used in the field of anti-cancer, so many people have some understanding of these two rare ginsenosides. This also makes many people have a misunderstanding about rare ginsenosides, thinking that there are only these two rare ginsenosides with anti-cancer effects.

In fact, in foreign countries, the anti-cancer applications of rare ginsenosides have long surpassed the two kinds of rh2 and rg3, rk2, rg5, rk1, rk3, rh1, rh3, rh4, appt, appd and other rare ginsenosides, all have related anti-cancer products, and even have products that aggregate a variety of rare ginsenosides together.

Comparison of the activity of rare ginsenosides.

Since so many rare ginsenosides have been used in anti-cancer products, people can't help but ask, who is stronger and who is weaker in the activity of these rare ginsenosides?

Canadian scientists experimentally determined the activity of some rare ginsenosides and compared them, and the results are as follows:

RG3 < 20-22)ppd = rg5 appt = rk1 and rg5 mixture = rh2 20-21)ppd < appd = δ(20-21)ppt = δ(20-22)ppt = rk2 and rh3 mixture rk2 = δ(20-21) ppd and δ(20-22) ppd mixture.

Many people are curious about what the total saponins of ginseng fruit are and what they do, in fact, it is an extract of ginseng fruit, which is a powdered substance that plays a beneficial role in human health, but it is not suitable for infants and pregnant women. Eating it in moderation can enhance immunity, inhibit cancer cells, prevent and treat Alzheimer's disease, avoid cerebral ischemia and beautify the skin, protect people's health, and enable them to live a better life.

Many people have heard of ginseng fruit, but they don't know what ginseng fruit saponins are, in fact, ginseng fruit saponins are an extract of ginseng fruit, presented in powder, it exists in the roots, stems and leaves of ginseng, and ginseng, has a variety of beneficial effects and effects on human health.

Usually moderate consumption of ginseng fruit saponins will not have any harmful effects, but for infants and pregnant women, they are not suitable for eating ginseng fruit saponins, which will make infants unable to accept their nutrients and have high fever and death, pregnant women will also appear unwell, which will have an impact on the fetus.

1. Enhance immunity

Ginseng fruit saponins containing a variety of nutrients are very beneficial to people's health, can promote the synthesis of RNA and DNA substances in the body, keep people full of energy and vitality, and eliminate people's physical fatigue and enhance their body immunity.

2. Inhibit cancer cells

Among the functions of ginseng fruit saponins, it can also inhibit cancer cells, so that they no longer move at will, avoid the spread of cancer cells, and can induce cancer cells to die. Therefore, the consumption of ginseng fruit saponins can also play an effective role in the prevention of cancer.

3. Prevention and treatment of Alzheimer's disease

For the elderly, eating ginseng fruit saponins has a good effect of prolonging life, in addition to a good effect on the prevention and treatment of Alzheimer's disease, which has beneficial ingredients, which can enhance the memory of the elderly, so as to effectively resist aging and avoid memory loss.

4. Avoid cerebral ischemia

In fact, in the role of ginseng fruit saponins, it can also avoid the appearance of cerebral ischemia, after eating ginseng fruit saponins, the material components in it can effectively help people resist cerebral blood damage, so as to increase people's cerebral blood volume and avoid brain deficiency death.

5. Beauty and beauty

Ginseng fruit saponins are also very suitable for women to eat, its lipophilic, hydrophilic, can well regulate the balance of oil and water, and can promote the human body's blood circulation, so that it can discharge toxins to keep the smooth and white skin with elasticity, has a good beauty effect.

Now there are more domestic products, and there are also foreign products entering China, how to choose when users choose ginsenoside products, and what indicators to see?

Indicator 1: Total ginsenoside content.

It is the total amount of ginsenosides contained in the product. The higher the ginsenoside content, the better the effect.

But there is a misunderstanding to be aware of. Since many ginsenoside products in the domestic market are monomeric ingredients, they only contain one ginsenoside, mainly Rh2 or Rg3. This is because these two ginsenosides were developed relatively early and are relatively easy to extract and prepare.

Many people only know Rh2 or Rg3, and when choosing a product, they only look at the content of Rh2 or Rg3. However, in fact, scientific research at home and abroad has found many ginsenosides with higher activity than Rh2 and Rg3, such as RK2, RH3, RK1, RG5, APPD, APPT, etc. At present, products containing a variety of highly active ginsenosides have appeared abroad.

So you can't just look at the content of Rh2 or Rg3, but also the total content of ginsenosides.

Indicator 2: Strength of ginsenoside activity.

The activity of different ginsenosides is different, and scientists have determined the contrast of ginsenoside activity. Choose ginsenosides with high activity. Scientists have determined the strength and weakness of ginsenosides as follows:

Indicator 3: Number of types of ginsenosides.

At present, scientists have discovered more than 30 kinds of ginsenosides with anti-cancer effects. Different ginsenosides have different anti-cancer effects, such as some have a strong effect on inhibiting tumor cell proliferation, some have a strong effect on inducing tumor cell apoptosis, and some are better at reducing chemoradiotherapy. In the process of fighting cancer, it is often necessary for a variety of effects to play a role together in order to have a better anti-cancer effect.

Therefore, foreign ginsenoside products are often multi-component, that is, they contain a variety of ginsenosides. Most of the domestic ones are single ingredients, which is actually caused by the backward level of technology and scientific research. So multi-component is better than single component.

Indicator 4: product dosage form.

The dosage form affects the absorption efficiency of ginsenosides. The injection is the best, the drop pill is the second, the capsule is again, and the powder directly is the worst.

It has to be said that there is still a relatively large gap between domestic and foreign research and application of ginsenosides. Foreign countries have developed a variety of highly active products, but China is still in the era of Rh2 and RG3, the activity of these two kinds of ginsenosides is ranked very low, and because there is no standard products of these ginsenosides such as RK2 and RH3 in China, most testing institutions cannot even detect ginsenosides other than RH2 and RG3.

First, the selection of product ingredients.

Many products don't have more ingredients that work better. The more singular the ingredient, the better the absorption. Ginsenosides contain Rh2, Rg3, Rb1, RK5, etc., all of which have different degrees of effect, but the absorption rate of ginsenoside Rg3 is only 3%, and the rg3 desaccharides are desaccharides, and only monosaccharides are left when ginsenoside rh2, and the bioavailability is about 16%, so the absorption rate of ginsenoside rh2 is five times that of rg3.

2. Select the dosage form of gastric dissolved capsules.

Ginsenoside Rh2 is mainly absorbed in the jejunum, and gastric dissolving capsules can retain ginsenoside Rh2 to the stomach and open it in the stomach to ensure that it is absorbed by the jejunum as soon as it enters the intestine. Ginsenoside RH2 is a natural small molecule, which almost completely removes sugar molecules, is lipophilic, easy to penetrate the blood-brain barrier, and can be taken for a long time.

3. Choose regular products with indicated content.

There is no indication of the content of the product is not guaranteed safety, ginsenoside rh2 is an active molecule, can only apply for the national food health word and the national medicine quasi-word, can not apply for food, at present, there are domestic businesses to provide test reports with a high content, and query the production license or product approval to the national food and drug administration network verification, it is actually ginseng tablet candy or ginsenoside powder. Food is only used to provide nutrients to the human body and has no functional function. Otherwise, why is it called food?

All products can go to the Food and Drug Administration Network for verification, after all, it is an oral ingredient, or it is better to be cautious, you can't just listen to the merchant's propaganda and believe that if the content of the ingredients advertised by the merchant is inconsistent with the actual food and Drug Administration network filing ingredients, you don't need to consider it.

Fourth, about imported products.

Each country has a similar food and drug administration, but many Chinese people do not know how to check and identify, and have always thought that imported products are good, and now China is not the China of a few decades ago, and many domestic products are no less than foreign products.